This volume includes the lectures delivered during the 2024 edition of the International School of Physics "Enrico Fermi" as part of the course Nuclear Physics from a Broad Perspective. Dedicated to the memory of Ricardo A. Broglia, this book reflects his extensive scientific interests in quantum many-body systems. The lectures cover a diverse range of topics in nuclear structure and reactions both from the theoretical and experimental point of view, including ab initio and density functional methods, collective excitations, shape coexistence, fission, gamma spectroscopy, direct reaction theory, pairing phenomena in nuclei and other fermionic systems.