Atul Jain - Böcker

Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges comprehensively reviews various biomaterials and biomaterial-derived carrier systems, with a specific focus on their application in drug delivery, and their clinical and regulatory challenges. A broad range of biomaterials for drug delivery are covered, including natural biomaterials, inorganic biomaterials, synthetic biomaterials, 3-D/4-D printed biomaterials, metal-based biomaterials, and polymeric and lipidic biomaterials. Various drug delivery approaches are detailed, from pulmonary and transdermal through to oral and systemic. Key to translational success of these novel platforms are the regulatory and clinical aspects of biomaterials development and application; these aspects are covered in each chapter, providing vital insight required to make informed decisions. Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges is an interesting resource for researchers and academics in the fields in biomaterials, materials science, polymer science, and pharmaceutical science, as well as clinicians and R&D groups with an interest in the development of novel biomaterials for drug delivery.Reviews a broad range of biomaterials, including natural (inorganic and metal-based), synthetic polymers, and lipidsExplores the interactions and mechanisms of action for various delivery methods, such as oral, transdermal, and ocular deliveryDelves into the clinical challenges and regulatory aspects of biomaterials development and application in drug delivery

This book covers several aspects of the fatigue behavior of textile and short fiber reinforced composites. The first part is dedicated to 2D and 3D reinforced textile composites and includes a systematic description of the damage evolution for quasi-static and tensile-tensile fatigue loadings. Acoustic emissions and digital image correlation are considered in order to detect the damage modes’ initiation and development. The acoustic emission thresholds of the quasi-static loading are connected to the “fatigue limit” of the materials with distinctions for glass and carbon reinforcements.The second part is devoted to the fatigue behavior of injection molded short fiber reinforced composites. Experimental evidence highlights the dependence of their fatigue response on various factors: fiber and matrix materials, fiber distribution, environmental and loading conditions are described. A hybrid (experimental/simulations) multi-scale method is presented, which drastically reduces the amount of experimental data necessary for reliable fatigue life predictions.