Colin J. Suckling – författare

The use of modelling techniques in the analysis and solution of problems in science and other fields of knowledge is widespread and has often come under intensive scrutiny. This 1978 book concerns the use of models in learning, understanding, and practising chemistry. It will therefore be of interest to chemists, biochemists and chemical engineers in research and industry, and to many students of chemical science. The chemist uses models in his work not only in the material sense, for example molecular models, but also in his patterns of thought, coming to grips with chemistry and its applications through the manipulation of models. The present work outlines the scope of modelling and, from a discussion of the general principles involved, develops themes relevant to both academic and industrial scientists.

In the molecular sciences, enzyme chemistry occupies a special niche as one of the major contact points between chemical and biological disciplines. The special properties of enzymes as selective and efficient catalysts are so central to current challenges to chemists that the development of enzyme chemistry in the past thirty years has been a major stimulus to chemical research in general. On the one hand studies of the intrinsic properties of enzymes and, on the other hand, their applications to synthesis, drug design, and biosynthesis have had an immense impact. This book brings together in one volume essays describing several such fields with emphasis on the applications. It would be unnecessarily repetitious to outline the approach and contents of the book in a Preface; the first short chapter is more eloquent than a formal Preface can be. I shall therefore encourage you to begin with the Introduction in Chapter 1 and here I wish to extend my warm thanks to those who have contributed to the production of this book: the authors for their acceptance of the overall concept of the book and for the thoughtfulness of their writing; Dr Charles Suckling, FRS and Professor Hamish Wood for their constructive criticism of the whole book; and Dr John Buckingham and his colleagues at Chapman and Hall for their efficiency and enthusiasm in transforming the typescripts into the book that you now hold. Colin J. Suckling University of Strathclyde Contributors Donald H.