Huzefa Rangwala – författare
Introduction to Protein Structure Prediction
Methods and Algorithms
1 791 kr
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A look at the methods and algorithms used to predict protein structure
A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology.
With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered:
Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutantWhether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.
2 000 kr
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A look at the methods and algorithms used to predict protein structure
A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology.
With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered:
Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutantWhether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.
2 299 kr
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654 kr
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757 kr
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Learning Analytics in Higher Education provides a foundational understanding of how learning analytics is defined, what barriers and opportunities exist, and how it can be used to improve practice, including strategic planning, course development, teaching pedagogy, and student assessment. Well-known contributors provide empirical, theoretical, and practical perspectives on the current use and future potential of learning analytics for student learning and data-driven decision-making, ways to effectively evaluate and research learning analytics, integration of learning analytics into practice, organizational barriers and opportunities for harnessing Big Data to create and support use of these tools, and ethical considerations related to privacy and consent. Designed to give readers a practical and theoretical foundation in learning analytics and how data can support student success in higher education, this book is a valuable resource for scholars and administrators.
757 kr
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Learning Analytics in Higher Education provides a foundational understanding of how learning analytics is defined, what barriers and opportunities exist, and how it can be used to improve practice, including strategic planning, course development, teaching pedagogy, and student assessment. Well-known contributors provide empirical, theoretical, and practical perspectives on the current use and future potential of learning analytics for student learning and data-driven decision-making, ways to effectively evaluate and research learning analytics, integration of learning analytics into practice, organizational barriers and opportunities for harnessing Big Data to create and support use of these tools, and ethical considerations related to privacy and consent. Designed to give readers a practical and theoretical foundation in learning analytics and how data can support student success in higher education, this book is a valuable resource for scholars and administrators.
561 kr
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708 kr
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This SpringerBrief covers the technical material related to large scale hierarchical classification (LSHC). HC is an important machine learning problem that has been researched and explored extensively in the past few years. In this book, the authors provide a comprehensive overview of various state-of-the-art existing methods and algorithms that were developed to solve the HC problem in large scale domains. Several challenges faced by LSHC is discussed in detail such as:
1. High imbalance between classes at different levels of the hierarchy
2. Incorporating relationships during model learning leads to optimization issues
3. Feature selection
4. Scalability due to large number of examples, features and classes
5. Hierarchical inconsistencies
6. Error propagation due to multiple decisions involved in making predictions for top-down methods
The brief also demonstrates how multiple hierarchies can be leveraged forimproving the HC performance using different Multi-Task Learning (MTL) frameworks.
The purpose of this book is two-fold:
1. Help novice researchers/beginners to get up to speed by providing a comprehensive overview of several existing techniques.
2. Provide several research directions that have not yet been explored extensively to advance the research boundaries in HC.
New approaches discussed in this book include detailed information corresponding to the hierarchical inconsistencies, multi-task learning and feature selection for HC. Its results are highly competitive with the state-of-the-art approaches in the literature.
Medical Image Computing and Computer Assisted Intervention – MICCAI 2023 Workshops
ISIC 2023, Care-AI 2023, MedAGI 2023, DeCaF 2023, Held in Conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8–12, 2023, Proceedings
834 kr
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This double volume set LNCS 14393-14394 constitutes the proceedings from the workshops held at the 26th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2023 Workshops, which took place in Vancouver, BC, Canada, in October 2023.
The 54 full papers together with 14 short papers presented in this volume were carefully reviewed and selected from 123 submissions from all workshops.The papers of the workshops are presenting the topical sections:
Eighth International Skin Imaging Collaboration Workshop (ISIC 2023) First Clinically-Oriented and Responsible AI for Medical Data Analysis (Care-AI 2023) Workshop First International Workshop on Foundation Models for Medical Artificial General Intelligence (MedAGI 2023) Fourth Workshop on Distributed, Collaborative and Federated Learning (DeCaF 2023) First MICCAI Workshop on Time-Series Data Analytics and Learning First MICCAI Workshop on Lesion Evaluation and Assessment with Follow-Up (LEAF) AI For Treatment Response Assessment and predicTion Workshop (AI4Treat 2023) Fourth International Workshop on Multiscale Multimodal Medical Imaging (MMMI 2023) Second International Workshop on Resource-Effcient Medical Multimodal Medical Imaging Image Analysis (REMIA 2023)