Onkar N. Singh - Böcker

This book will shape the course of electromagnetics research for decades to come. Fourteen leading researchers from five countries reveal their latest research results in detail and review parallel developments. The topics discussed, though unconventional today, are destined to attract great attention as shrinking device sizes make electromagnetic effects ever more important. These topics include the rotation of polarization of electric waves by a twisted structure; homogenization of linear bianistotropic composite materials; novel free-space techniques to characterize complex mediums; sculptured thin films; electrodynamic properties of carbon nanotubes; and more. Electromagnetic Fields in Unconventional Materials and Structures:* Focuses on geometry in both large and small scales* Provides a blueprint for electromagnetics research at the turn of the century* Features new results, comments, and prognostications on 21st century research* Includes more than 150 illustrations as well as hundreds of charts, tables, and references

The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.

The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.

Scientific evidence clearly shows that chlorine and bromine compounds, such as CFCs, released into the atmosphere are responsible for continuous and progressive global ozone losses superimposed by dramatic seasonal ozone depletions first observed over Antarctica, now occurring over Arctic regions as well. Today substitutes are produced and emitted, some of which are highly reactive substances. This handbook volume deals with these reactive halogen compounds and their interactions. It provides a review on the present knowledge of their properties, applications, sources, sinks as well as international regulations.