R. Stein – författare

There has been a convergence in recent years of people from the physical and biological sciences and from various engineering disciplines who are interested in analyzing the electrical activity of nerve and muscle quantita­ tively. Various courses have been established at the graduate level or final-year undergraduate level in many universities to teach this subject matter, yet no satisfactory short text has existed. The present book is an attempt to fill this gap, and arises from my experience in teaching this material over the past fifteen years to students on both sides of the Atlantic. Although covering a wide range of biophysi­ cal topics from the level of single molecules to that of complex systems, I have attempted to keep the text relatively short by considering only examples of the most general interest. Problems are included whenever possible at the end of each chapter so the reader may test his understand­ ing of the material presented and consider other examples which have not been included in the text.

Although it is generally accepted that the Arctic Ocean is a very sensitive and important region for changes in the global climate, this region is the last major physiographic province of the earth whose short-and long-term geological history is much less known in comparison to other ocean regions. This lack of knowledge is mainly caused by the major technological/logistic problems in reaching this harsh, ice-covered region with normal research vessels and in retrieving long and undisturbed sediment cores. During the the last about 20 years, however, several international and multidisciplinary ship expeditions, including the first scientific drilling on Lomonosov Ridge in 2004, a break-through in Arctic research, were carried out into the central Artic and its surrounding shelf seas. Results from these expeditions have greatly advanced our knowledge on Arctic Ocean paleoenvironments. Published syntheses about the knowledge on Arctic Ocean geology, on the other hand, are based on data available prior to 1990. A comprehensive compilation of data on Arctic Ocean paleoenvironment and its short-and long-term variability based on the huge amount of new data including the ACEX drilling data, has not been available yet. With this book, presenting (1) detailed information on glacio-marine sedimentary processes and geological proxies used for paleoenvironmental reconstructions, and (2) detailed geological data on modern environments, Quaternary variability on different time scales as well as the long-term climate history during Mesozoic-Tertiary times, this gap in knowledge will be filled.*Aimed at specialists and graduates *Presents background research, recent developments, and future trends*Written by a leading scholar and industry expert

Within the joint German-Russian research project "Siberian River Run-off (SIRRO)" multidisciplinary studies were carried out in the Ob and Yenisei estuaries and adjacent southern Kara Sea (Arctic Ocean). The overall goal of the project was to extend knowledge on understanding the freshwater and sediment input by the major Siberian rivers and its impact on the environments of the inner Kara Sea. The main results of oceanographical, biological, geochemical, geological and modelling studies are presented in four main chapters:(A) Modern Discharge: Data and modelling; (B) Discharge and biological processes, (C) Discharge and organic carbon cycle, and (D) Discharge and sediment records.

Although it is generally accepted that the Arctic Ocean is a very sensitive and important region for changes in the global climate, this region is the last major physiographic province of the earth whose short-and long-term geological history is much less known in comparison to other ocean regions. This lack of knowledge is mainly caused by the major technological/logistic problems in reaching this harsh, ice-covered region with normal research vessels and in retrieving long and undisturbed sediment cores. During the the last about 20 years, however, several international and multidisciplinary ship expeditions, including the first scientific drilling on Lomonosov Ridge in 2004, a break-through in Arctic research, were carried out into the central Artic and its surrounding shelf seas. Results from these expeditions have greatly advanced our knowledge on Arctic Ocean paleoenvironments. Published syntheses about the knowledge on Arctic Ocean geology, on the other hand, are based on data available prior to 1990. A comprehensive compilation of data on Arctic Ocean paleoenvironment and its short-and long-term variability based on the huge amount of new data including the ACEX drilling data, has not been available yet. With this book, presenting (1) detailed information on glacio-marine sedimentary processes and geological proxies used for paleoenvironmental reconstructions, and (2) detailed geological data on modern environments, Quaternary variability on different time scales as well as the long-term climate history during Mesozoic-Tertiary times, this gap in knowledge will be filled.Aimed at specialists and graduatesPresents background research, recent developments, and future trendsWritten by a leading scholar and industry expert

R. B. Stein Department of Physiology, University of Alberta, Edmonton, Canada The impetus for this volume and the conference that gave rise to it was the feeling that studies on motor control had reached a turning point. In recent years, studies on motor units and muscle receptors have become increasingly detailed. Attempts to integrate these studies into quantitative models for the spinal control of posture have appeared and preliminary attempts have been made to include the most direct supraspinal pathways into these models (see for example the chapters by Nashner and Melvill Jones et al. in this volume). Thus, we felt that the time was ripe to summarize these developments in a way which might be useful not only to basic medical scientists, but also to clinicians dealing with disorders of motor control, and to bioengineers attempting to build devices to assist or replace normal control. Over the past few years, computer methods have also made possible increasingly detailed studies of mammalian locomotion, and improved physiological and pharmacological studies have appeared. There seems to be almost universal agreement now that the patterns for locomotion are generated in the spinal cord, and that they can be generated with little, if any, phasic sensory information (see chapters by Grillner and Miller et al. ). This concludes a long controversy on whether chains of reflexes or central circuits generate stepping patterns. The nature of the pattern generators in mammals remains obscure, but invertebrate studies on locomotion have recently made striking advances.

R. B. Stein Department of Physiology, University of Alberta, Edmonton, Canada The impetus for this volume and the conference that gave rise to it was the feeling that studies on motor control had reached a turning point. In recent years, studies on motor units and muscle receptors have become increasingly detailed. Attempts to integrate these studies into quantitative models for the spinal control of posture have appeared and preliminary attempts have been made to include the most direct supraspinal pathways into these models (see for example the chapters by Nashner and Melvill Jones et al. in this volume). Thus, we felt that the time was ripe to summarize these developments in a way which might be useful not only to basic medical scientists, but also to clinicians dealing with disorders of motor control, and to bioengineers attempting to build devices to assist or replace normal control. Over the past few years, computer methods have also made possible increasingly detailed studies of mammalian locomotion, and improved physiological and pharmacological studies have appeared. There seems to be almost universal agreement now that the patterns for locomotion are generated in the spinal cord, and that they can be generated with little, if any, phasic sensory information (see chapters by Grillner and Miller et al. ). This concludes a long controversy on whether chains of reflexes or central circuits generate stepping patterns. The nature of the pattern generators in mammals remains obscure, but invertebrate studies on locomotion have recently made striking advances.