William Craig Stagner – författare

This work is an examination of all aspects of the science in developing effective dosage form for drug delivery

Pharmaceutics refers to the subfield of pharmaceutical sciences that develops drug delivery products or devices to optimize the drug''s performance once administered. This multidisciplinary field draws on physical chemistry, organic chemistry, and biophysics to generate and refine these crucial elements of medical care. Moreover, incorporating such disparate dimensions of drug product design as material properties and legal regulation bridges the gap between effective chemicals and viable medical treatments.

Integrated Pharmaceutics provides a comprehensive introduction to the creation and manufacture of effective dosage forms for drug delivery. It presents its subject following the principles of physical pharmacy, product design, and drug regulations. This tripartite structure allows readers to move from theory to practice, beginning from a firm foundation of physical pharmacy principles, including drug solubility and stability estimation, rheology, and interfacial properties. From there, it proceeds to discussions of drug product design and of harmonizing pharmaceutical design with the regulatory regimens and technological standards of the United States, European Union, and Japan.

Readers of the second edition of Integrated Pharmaceutics will also find:

A glossary defining key terms, extensive informative appendices, and a list of references leading to the primary literature in the field for each chapter Earlier chapters are expanded, with additional new chapters including one entitled “Biotechnology Products” Supplementary instructor guide with questions and solutions available online for registered professors Updated regulatory guidelines including quality by design, design space analysis, process analytical technology, polymorphism characterization, blend sample uniformity, and stability protocols

Integrated Pharmaceutics is a useful textbook for graduate students in pharmaceutical sciences, drug formulation and design, and biomedical engineering. In addition, professionals in the pharmaceutical industry, including regulatory bodies, will find it a helpful reference guide.

This work is an examination of all aspects of the science in developing effective dosage form for drug delivery Pharmaceutics refers to the subfield of pharmaceutical sciences that develops drug delivery products or devices to optimize the drug's performance once administered. This multidisciplinary field draws on physical chemistry, organic chemistry, and biophysics to generate and refine these crucial elements of medical care. Moreover, incorporating such disparate dimensions of drug product design as material properties and legal regulation bridges the gap between effective chemicals and viable medical treatments. Integrated Pharmaceutics provides a comprehensive introduction to the creation and manufacture of effective dosage forms for drug delivery. It presents its subject following the principles of physical pharmacy, product design, and drug regulations. This tripartite structure allows readers to move from theory to practice, beginning from a firm foundation of physical pharmacy principles, including drug solubility and stability estimation, rheology, and interfacial properties. From there, it proceeds to discussions of drug product design and of harmonizing pharmaceutical design with the regulatory regimens and technological standards of the United States, European Union, and Japan. Readers of the second edition of Integrated Pharmaceutics will also find: A glossary defining key terms, extensive informative appendices, and a list of references leading to the primary literature in the field for each chapterEarlier chapters are expanded, with additional new chapters including one entitled “Biotechnology Products”Supplementary instructor guide with questions and solutions available online for registered professorsUpdated regulatory guidelines including quality by design, design space analysis, process analytical technology, polymorphism characterization, blend sample uniformity, and stability protocolsIntegrated Pharmaceutics is a useful textbook for graduate students in pharmaceutical sciences, drug formulation and design, and biomedical engineering. In addition, professionals in the pharmaceutical industry, including regulatory bodies, will find it a helpful reference guide.

This work is an examination of all aspects of the science in developing effective dosage form for drug delivery

Pharmaceutics refers to the subfield of pharmaceutical sciences that develops drug delivery products or devices to optimize the drug''s performance once administered. This multidisciplinary field draws on physical chemistry, organic chemistry, and biophysics to generate and refine these crucial elements of medical care. Moreover, incorporating such disparate dimensions of drug product design as material properties and legal regulation bridges the gap between effective chemicals and viable medical treatments.

Integrated Pharmaceutics provides a comprehensive introduction to the creation and manufacture of effective dosage forms for drug delivery. It presents its subject following the principles of physical pharmacy, product design, and drug regulations. This tripartite structure allows readers to move from theory to practice, beginning from a firm foundation of physical pharmacy principles, including drug solubility and stability estimation, rheology, and interfacial properties. From there, it proceeds to discussions of drug product design and of harmonizing pharmaceutical design with the regulatory regimens and technological standards of the United States, European Union, and Japan.

Readers of the second edition of Integrated Pharmaceutics will also find:

A glossary defining key terms, extensive informative appendices, and a list of references leading to the primary literature in the field for each chapter Earlier chapters are expanded, with additional new chapters including one entitled “Biotechnology Products” Supplementary instructor guide with questions and solutions available online for registered professors Updated regulatory guidelines including quality by design, design space analysis, process analytical technology, polymorphism characterization, blend sample uniformity, and stability protocols

Integrated Pharmaceutics is a useful textbook for graduate students in pharmaceutical sciences, drug formulation and design, and biomedical engineering. In addition, professionals in the pharmaceutical industry, including regulatory bodies, will find it a helpful reference guide.

Comprehensive reference reviewing how thermodynamic principles underpin the design of drug products and their applications Written in an easy-to-read and understand style, Thermodynamics for Drug Product Design offers an abundance of real-life drug product design examples, applications, personal anecdotes, and solved problems that contextualize thermodynamic principles for the drug product design scientist. Advanced undergraduate and beginning graduate students will learn to apply thermodynamic principles to create robust drug products and to predict, prevent, analyze, and evaluate the root cause of product failures. Professionals engaged in drug product design will find this book to be a rich and easy to use reference guide. The first two chapters address some key basics of data reporting and analysis, math, and thermodynamic properties using simple and accessible language. These chapters also help readers understand fundamental underlying definitions and physical relationships required to use thermodynamic laws in the design of drug products. In later chapters, the book focuses on six industrial pharmacy relevant thermodynamic topics: the laws of thermodynamics, Gibbs free energy, equilibrium, drug solubility equilibrium, surface thermodynamics, and adsorption phenomena. Thermodynamics for Drug Product Design features chapters including: Data Reporting and AnalysisUnderlying Thermodynamic Physical Property Relationships and DefinitionsThe Laws of ThermodynamicsGibbs Free EnergyEquilibriumDrug Solubility EquilibriumSurface ThermodynamicsAdsorption PhenomenaWhat others say: “…comprehensive, rigorous, and logically organized …the explanations flow effortlessly from the page…”—BRUNO HANCOCK, PhD, FAAPS, Editor, JPharmSci “…has a unique style of communicating complex scientific issues…”—KEN MORRIS, PhD, FAAPS, Professor Emeritus, Founding Director Lachman Institute “…unusual wide range of subjects…unusual for detail…”—DALE ERIC WURSTER, PhD, FAAPS, Professor Emeritus, 2019 AAPS President

Comprehensive reference reviewing how thermodynamic principles underpin the design of drug products and their applications Written in an easy-to-read and understand style, Thermodynamics for Drug Product Design offers an abundance of real-life drug product design examples, applications, personal anecdotes, and solved problems that contextualize thermodynamic principles for the drug product design scientist. Advanced undergraduate and beginning graduate students will learn to apply thermodynamic principles to create robust drug products and to predict, prevent, analyze, and evaluate the root cause of product failures. Professionals engaged in drug product design will find this book to be a rich and easy to use reference guide. The first two chapters address some key basics of data reporting and analysis, math, and thermodynamic properties using simple and accessible language. These chapters also help readers understand fundamental underlying definitions and physical relationships required to use thermodynamic laws in the design of drug products. In later chapters, the book focuses on six industrial pharmacy relevant thermodynamic topics: the laws of thermodynamics, Gibbs free energy, equilibrium, drug solubility equilibrium, surface thermodynamics, and adsorption phenomena. Thermodynamics for Drug Product Design features chapters including: Data Reporting and AnalysisUnderlying Thermodynamic Physical Property Relationships and DefinitionsThe Laws of ThermodynamicsGibbs Free EnergyEquilibriumDrug Solubility EquilibriumSurface ThermodynamicsAdsorption Phenomena What others say: comprehensive, rigorous, and logically organized the explanations flow effortlessly from the page BRUNO HANCOCK, PhD, FAAPS, Editor, JPharmSci has a unique style of communicating complex scientific issues KEN MORRIS, PhD, FAAPS, Professor Emeritus, Founding Director Lachman Institute unusual wide range of subjects unusual for detail DALE ERIC WURSTER, PhD, FAAPS, Professor Emeritus, 2019 AAPS President