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​This book both summarizes the basic theory of evolutionary games and explains their developing applications, giving special attention to the 2-player, 2-strategy game. This game, usually termed a "2×2 game” in the jargon, has been deemed most important because it makes it possible to posit an archetype framework that can be extended to various applications for engineering, the social sciences, and even pure science fields spanning theoretical biology, physics, economics, politics, and information science. The 2×2 game is in fact one of the hottest issues in the field of statistical physics. The book first shows how the fundamental theory of the 2×2 game, based on so-called replicator dynamics, highlights its potential relation with nonlinear dynamical systems. This analytical approach implies that there is a gap between theoretical and reality-based prognoses observed in social systems of humans as well as in those of animal species. The book explains that this perceived gap is theresult of an underlying reciprocity mechanism called social viscosity. As a second major point, the book puts a sharp focus on network reciprocity, one of the five fundamental mechanisms for adding social viscosity to a system and one that has been a great concern for study by statistical physicists in the past decade. The book explains how network reciprocity works for emerging cooperation, and readers can clearly understand the existence of substantial mechanics when the term "network reciprocity" is used. In the latter part of the book, readers will find several interesting examples in which evolutionary game theory is applied. One such example is traffic flow analysis. Traffic flow is one of the subjects that fluid dynamics can deal with, although flowing objects do not comprise a pure fluid but, rather, are a set of many particles. Applying the framework of evolutionary games to realistic traffic flows, the book reveals that social dilemma structures lie behind traffic flow.

The First International Symposium on "Pain and Kampo (Japanese Herbal Medicine)" took place in Tokyo in October, 1992. More than 700 registrants participated, with 12 registrants from seven overseas countries. This book contains summaries of the presentations at this meeting and is published in order to provide up-to-date information to a much wider audience. In China, traditional herbal medicine has been used for more than 3000 years while in Japan, its use has been documented for more than 1000 years, albeit with some changes to the original Chinese formulations. Recently there has been a revival of interest in herbal medicines for several reasons. There is a rapid growth in the number of senior citizens who frequently require the attention of modern medicine. In particular, there has been an increase in the number of patients who suffer from chronic diseases which are difficult to treat, e.g., arteriosclerosis, Alzheimer's disease, chronic pain syndromes, etc. It has become evident that traditional Oriental herbal medicines could playa role in the management of these and other conditions.

Sika deer, the graceful spotted deer of Japanese and Chinese art, originally were native to Asia from far-east Russia to Vietnam to the islands of Japan and Taiwan. They are widely raised in captivity to supply velvet antler for traditional medicine. They also were introduced to Europe, North America, and New Zealand, where they compete or interbreed with native deer. Sika deer typically occupy lowland hardwood forests with low winter snow depths, where they thrive in sites disturbed by fire, storm, or logging. In high numbers they can severely impact vegetation though overgrazing, stripping bark from trees and damaging crop fields and forest plantations. Their numbers are high in many parts of Japan, moderate in Russia, and reduced or extinct in the wild in China, Korea, Vietnam, and Taiwan. This book explores their basic biology, behavior, and ecology, including management for sport hunting, conservation or recovery of threatened populations, and resolution of conflict with humans in native and introduced lands.

Combining harmonic technology and an ultrasound contrast agent, harmonic imaging now plays a vital role in the diagnosis and treatment of hepatic tumors. Contrast harmonic imaging is especially valuable in cases of hepatocellular carcinoma (HCC), the incidence of which has risen dramatically in Europe, North America, and Asia in recent years. Harmonic imaging is bringing about revolutionary changes in the diagnosis and treatment of HCC, and this book provides the most up-to-date information and guidelines for effective use of this superior technique. Generously illustrated with photographs and diagrams, with accompanying text by a leading expert in the field, this acclaimed book is a valuable state-of-the-art resource for clinicians and researchers in radiology and internal medicine, including hepatology and gastroenterology.

Japan’s traditional and fragile satoyama landscape system was developed over centuries of human life on mountainous island terrain in a monsoon climate. The carefully managed coppice woodlands on the hillsides, the villages strung along the base of the hills, and the carefully tended paddy fields of rural Japan made possible the sustainable interaction of nature and humans. Radical changes in the middle of the twentieth century led to the abandonment of satoyama landscapes which now are being rediscovered. There is a new realization that these woodlands still play a vital role in the management of the Japanese landscape and a new determination to manage them for the future. This multifaceted book explores the history, nature, biodiversity, current conservation measures, and future uses of satoyama. The information presented here will be of interest in all parts of the world where patterns of sustainable development are being sought.

Carabid ground beetles, sometimes called "walking jewels", are among the most thoroughly investigated insects in the world. This book presents the results of molecular phylogenetic analyses of 2000 specimens, including 350 species and that cover more than 90% of the known genera, from 500 localities in 35 countries. These comprehensive analyses using mitochondrial DNA-based dating suggest that carabid diversification took place about 40 to 50 million years ago as an explosive radiation of the major genera, coinciding with the collision of the Indian subcontinent and Eurasian land mass. The analyses also lead to surprising conclusions suggesting discontinuous evolution and parallel morphological evolution. With numerous color illustrations, this book presents readers with the dynamic principles of evolution and the magnificent geographic history of the earth as revealed by the study of beetles.

The globalization of trade, monetary and fiscal policies, capital markets, and investment patterns is reshaping the world economy and is leading to new financial, commercial, and marketing structures as well as unprecedented economies of scale.

Vascular changes that occur in the human retina and choroid have frequently been studied through the use of light microscopy. This technique has marked limitations, however, in that it shows changes only in limited localized sites, often with the effects of various systemic diseases indistinguishable. Newer techniques of corrosion cast scanning electron microscopy and transmission electron microscopy provide a much clearer three-dimensional view of retinal and choroidal vasculatures, the results of which will be useful for the interpretation of ocular fundus changes seen in individual systemic diseases. Retinal and choroidal vascular changes due to aging, arteriosclerosis, spontaneous hypertension, and diabetes mellitus in the rat have been investigated and are described in this book, which will be of interest to those in the fields of ophthalmology, anatomy, and pathology. This book is a leading source of information on the use of electron microscopy in a new field of interest. .

The 15th International Symposium of the Japan Human Cell Society on Cell and Molecular Biology of Endometrial Carcinoma brought together leading researchers from Japan and around the world. The papers collected here are the work of twenty-two leaders in their field and are organized in ten major categories. The first section, in vitro experimental systems, takes up the pioneering work by Kuramoto in 1968 and Nishida in 1980 in establishing, respectively, the HEC-1 and hormone-responsive endometrial carcinoma cell lines. Other topics include apoptosis, proliferation, and growth factors; cell cycle regulators; signaling pathways; angiogenesis; carcinogenesis; hormones and hormone receptors; genes and gene expression; endometrial receptivity; and chemo-resistance and -sensitivity. Presenting the latest work in the cell and molecular biology of endometrial carcinoma, this volume is a valuable resource for gynecologists, pathologists, and molecular biologists.

Lake Baikal in eastern Siberia is a crucial site for detecting long-term global changes, owing to its high sensitivity to climatic oscillation and its extraordinarily long history. Because lacustrine sediments have an advantage in providing high-resolution information, the sediments in Lake Baikal contain excellent continuous records of past conditions including paleoclimates, evolution, and specification of organisms. Based on the study by the Baikal Drilling Project, this book provides information on global climatic and environmental changes for as much as 12 million years. The book also includes discussions of comparatively short-term changes such as glacial and interglacial transitions that directly link to the present and future environment. Long Continental Records from Lake Baikal summarizes the latest knowledge on the paleoenvironment and provides a foundation for further studies in global environmental changes.

A central goal of current biology is to decode the mechanisms that underlie the processes of morphogenesis and pattern formation. Concerned with the analysis of those phenomena, this book covers a broad range of research fields, including developmental biology, molecular biology, plant morphogenesis, ecology, epidemiology, medicine, paleontology, evolutionary biology, mathematical biology, and computational biology. In Morphogenesis and Pattern Formation in Biological Systems: Experiments and Models, experimental and theoretical aspects of biology are integrated for the construction and investigation of models of complex processes. This collection of articles on the latest advances by leading researchers not only brings together work from a wide spectrum of disciplines, but also provides a stepping-stone to the creation of new areas of discovery.

The Pasoh Forest Reserve (pasoh FR) has been a leading center for international field research in the Asian tropical forest since the 1970s, when a joint research project was carried out by Japanese, British and Malaysian research teams with the cooperation of the University of Malaya (UM) and the Forest Research Institute (FRI, now the Forest Research Institute Malaysia, FRIM) under the International Biological Program (IBP). The main objective of the project was to provide basic information on the primary productivity ofthe tropical rain forest, which was thought to be the most productive of the world's ecosystems. After the IBP project, a collaborative program between the University of Malaya and the University of Aberdeen, Scotland, UK, for post-graduate training was carried out at Pasoh. Reproductive biology of so me dipterocarp trees featured in many of the findings arrived at through the program, contributing greatly to progress in the population genetics of rain forest trees. Since those research pro grams, apart of the Pasoh forest and its field research station have been managed by FRIM. In 1984, FRIM started a long-term ecological research program in Pasoh FR with the Smithsonian Tropical Research Institute (STRI) and Harvard University, establishing a 50-ha plot and enumerating and mapping all trees 1 cm or more in diameter at breast height. A recensus has been conducted every 5 years.

Social sciences are moving to the next stage. One ofthe promising methodologies is agent-based computer simulation. In a series ofworkshops on Agent-Based Ap- proaches in Economic and Social Complex Systems (AESCS), ground-breaking studies of complex economic and social phenomena using computational approaches are being presented and discussed. This volume contains papers selected from pre- sentations at the AESCS '02 held at the University ofTokyo, Japan, on August 16, 2002. The workshop was the second in a series ofPacific Rim activities in interdis- ciplinary areas of social and computational sciences, the first workshop having been held in Shimane, Japan, May 21-22, 2001. The objective of AESCS workshops is to promote worldwide multidisciplinary activities in multiagent computational economics, organizational science, social dynamics, and complex systems. AESCS brings together researchers and practitio- ners from diverse fields, such as computer science, economics, physics, sociology, psychology, and complex theory, in order to understand emergent and collective phenomena in economic, organizational, and social systems.AESCS also provides an opportunity for discussion ofthe effectiveness and limitations ofcomputational models and methodologies for the social sciences. The second AESCS workshop focused on the importance ofcumulative progress in agent-based simulation in the social sciences through discussions ofcommon tasks, standard computational models, replication and validation issues, and evalu- ation and verification criteria for the results.

In the 5 years since the publication of Urologic Laparoscopy by the Japanese Society of Endourology and ESWL, the field has moved on apace, particularly technologically. It is with an eye on the need to disseminate the latest information on this progress that this collection has been assembled, highlighting the most recent advances in laparoscopic urologic oncology surgery. With treatment options becoming ever more complicated, it is essential to keep the prime objectives in mind - improved quality of life for the patient, minimal complications, early convalescence, and a better end result. In our effort to cover a broad range of techniques from renal cyst decortication to robotic laparoscopic camera control, we are in debt to surgeons at the forefront of treatment, not only in Japan but worldwide, and to manufacturers who are constantly innovating in their equipment. The contributors are enthusiastic in their expertise, as shown in the quality of the material they have produced.

The field of endoscopic spinal surgery has seen significant growth in recent years and has led to new and innovative surgical options that address several pathological conditions in the spinal column without running the risks commonly associated with open surgery. This book, as the result of the PASMISS (Pacific Asian Society of Minimally Invasive Spine Surgery) meeting held in Thailand in 2002, is a collection of the latest research by internationally recognized experts in the field. They discuss current techniques for performing endoscopic spine surgery, as well as examining thoracoscopic and laparoscopic techniques. Individual chapters address subjects as diverse as microdiscectomy, laparoscopic epidural surgery, and foraminoscopic spine surgery, The collected knowledge contained within this volume is sure to be of benefit to orthopedic surgeons interested in gaining knowledge of a wide range of new procedures.

Biologists and anthropologists in Japan have played a crucial role in the development of primatology as a scientific discipline. Publication of Primate Origins of Human Cognition and Behavior under the editorship of Tetsuro Matsuzawa reaffirms the pervasive and creative role played by the intellectual descendants of Kinji Imanishi and Junichiro Itani in the fields of behavioral ecology, psychology, and cognitive science. Matsuzawa and his colleagues-humans and other primate partners- explore a broad range of issues including the phylogeny of perception and cognition; the origin of human speech; learning and memory; recognition of self, others, and species; society and social interaction; and culture. With data from field and laboratory studies of more than 90 primate species and of more than 50 years of long-term research, the intellectual breadth represented in this volume makes it a major contribution to comparative cognitive science and to current views on the origin of the mind and behavior of humans.

Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of researchers in academia and industry interested in wider applications of IMS. Intended for beginners or those with limited experience with IMS technology, this book provides practical details and instructions needed for immediate know-how, including the preparation of animal tissue samples, the application of a matrix, instrumental operations, and data analysis, among others. By describing the foundations of IMS, this volume contributes to the ongoing development of the field and to progress in human health.

In ovo electroporation is an epoch-making achievement in the study of developmental biology. With this method, experiments can be carried out in gain and loss of function in desired tissue at any desired stage in chick embryos. Introduction of a tetracycline-regulated gene expression system and a transposon system has further extended the potential of the method, making it possible to obtain long-term expression and to turn on and off a gene of interest. It is now applied to mice, aquatic animals, and even to plants for the study of developmental biology and for other purposes. In this book, the application of electroporation in many embryonic tissues and organs is introduced, with some chapters that deal with gene transfer in adults. Sonoporation, another useful tool, using ultrasonic waves instead of electric currents, for gene transfer to mesenchymal tissues is also introduced.

Hiroshi Komiyama's "Vision 2050" is a plan for paving a road to global sustainability. It lays out a path to a sustainable future for humanity that could realistically be achieved by 2050 through the application of science and technology. A prominent Japanese academic and leader in global sustainability, Komiyama draws upon realistic assumptions and solid scientific concepts to create a vision that makes the living standards enjoyed by developed countries today possible for all people by 2050. "Vision 2050" is built upon three fundamental principles – increased energy efficiency, recycling, and development of renewable energy sources – and the book argues for the technological potential of all three. Specifically, Komiyama envisions a three-fold increase in overall energy efficiency and a doubling of renewable energy resources by 2050. "Vision 2050: Roadmap for a Sustainable Earth" is written to address the concerned citizen as well as to inspire an exchange of ideas among experts, policy makers, industrial leaders, and the general public.

Auditory neuropathy is gaining more attention as new findings come to light and as hearing screening of newborns has been introduced in many countries in the past decade. A compilation of research topics from around the world, this book provides the latest knowledge on the neuropathy of the auditory and vestibular eighth cranial nerves, with valuable information on pathophysiology and genetics, new subtypes, and recent research on cochlear implants in patients with auditory neuropathy, including children. Among the several major sections of the book, one presents neurological cases and another focuses on historical issues. Covering a wide range of related topics, the book provides a wealth of insights on this disease entity and on auditory and vestibular neuropathy in particular. It is a useful and informative reference for all those interested in and concerned with auditory nerve disease, especially for medical students, researchers, and clinicians.

Econophysics is a newborn field of science bridging economics and physics. A special feature of this new science is the data analysis of high-precision market data. In economics arbitrage opportunity is strictly denied; however, by observing high-precision data we can prove the existence of arbitrage opportunity. Also, financial technology neglects the possibility of market prediction; however, in this book you can find many examples of predicted events. There are other surprising findings. This volume is the proceedings of a workshop on "application of econophysics" at which leading international researchers discussed their most recent results.

As the shift from the Metal Age progresses, materials engineers and materials scientists seek new analytical and design methods to create stronger and more reliable materials. Based on extensive research and developmental work done at the author’s multi-disciplinary material laboratory, this graduate-level and professional reference addresses the relationship between fracture mechanisms (macroscale) and the microscopic, with the goal of explaining macroscopic fracture behavior based on a microscopic fracture mechanism. A careful fusion of mechanics and materials science, this text and monograph systematically considers an array of materials, from metals through ceramics and polymers, and demonstrates lab-tested strategies to develop desirable high-temperature materials for technological applications.

The groundwater science and engineering has been closely connected with various fields (1) Groundwater Hydrology, (2) Groundwater Hydraulics or Geohydraulics, (3) Fluid Dynamics in Porous Media, (4) Groundwater Quality Engineering, (5) Soil Physics, and (6) Hydrogeology or Geohydrology.The purpose of the book is to present an update textbook of groundwater hydraulics, which includes all of basic items in above-mentioned fields, to students (of graduate school), researchers and practitioners. The students and beginners who intend to specialize in groundwater hydraulics through one semester will master contents of the book.

Drastic changes of the societies in the new century require new paradigm in every area of social science. Organizations study is not exception. This book illustrates the cutting edge of organizations study beyond the traditional approaches in management science and general management theory. With an interdisciplinary approach emphasizing systemic properties of organizations such as interaction, hierarchy, network and emergence, it covers dynamic aspects of organizational learning and evolution as well as the decision making function and information processing process.

It is an honor and pleasure for me to write the foreword of this book comprising the of Forest Resources for proceedings of the Fourth Symposium on the Improvement Recyclable Forest Products. The symposium was organized by Dr. Toshihiro Ona, Associate Professor at the Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Japan, as part of the "Development of Forest Resources with High Performance for Paper Recycling" research project. This was supported by the Core Research for Evolutional Science and Technology (CREST) team at the Japan Science and Technology Agency Foundation (lST) and by Kyushu University. As a colleague of Dr. Ona, I commend his efforts in organizing the symposium and editing this book. In the forest, there is a multitude of resources, including trees, herbal plants, fruits, fungi, mammals, birds, insects, fishes, reptiles, water, landscapes, and tourist attractions. Nowadays, even the environment is regarded as a kind of forest resource. These resources can provide a diversity of forest products, such as timber for buildings, pulp and paper, charcoal, herbal medicines, wild vegetables, animal protein, edible mushrooms, and nonwoody fibers. From these resources, major forest products are produced using various species of trees. For example, softwood is suitable as building material, while hardwood is suitable for furniture production; pulp and paper are produced from both softwood and hardwood. Therefore, forest locations and forest management methods should vary according to the tree species used for production of different forest products.

As is represented by the world's top-level Japanese automotive manufacturers, Japanese manufacturers have been climbing to winning positions in global businesses. The driving force of their success includes responsiveness to diversifying market needs and elevating quality requirements, clarification of development concepts that facilitate new technology, application of technology to product planning and design, advanced production control systems that elaborately utilize state-of-the-art manufacturing technologies, and flexible, efficient production. Many Japanese manufacturers succeeded in fulfilling these factors mainly because they utilize Japanese-style Lean Production Systems or the so-called Toyota Production System (TPS) and Japanese-style, scientific quality management approaches such as Statistical Quality Control (SQC) and Total Quality Management (TQM) in order to improve their corporate management technology. As severe competition among manufacturers intensify both in Japan and overseas, action against quality problems that remarkably diminish customer satisfaction, and customer-first quality management, is becoming important. Scientific quality control methods that aim to optimize production processes for building in quality were undermined by the past expansion of quantity-oriented manufacturing through automation with massive and heavy equipment.

This book discusses Nature and Human Communities in the historical and social background of Asia. Part 1 deals with the problems of coexistence among human beings. Part 2 explores coexistence between human beings and nature. The text focuses on local/regional commitments to solve problems and integrate specialized knowledge. It considers the kinds of relationship between human communities and nature that may lead to a more balanced, sustainable future for both. Avian Influenza poses a looming threat for human and animal health. The old paradigm was that the disease in waterfowl, poultry, pigs and man was caused by separate viruses that stayed within their own niche. Deadly outbreaks have shattered this view. This timely reference examines such sensitive issues as regulation of low pathogenic and high pathogenic AI, surveillance of waterfowl, live bird markets, and outbreak control in densely populated areas.

In agent-based modeling the focus is very much on agent-based simulation, as simulation is a very important tool for agent-based modeling. We also use agent-based simulation in this book with a stress on the mathematical foundation of agent-based modeling. We introduce two original mathematical frameworks, a theory of SLD (Social Learning Dynamics) and an axiomatic theory of economic exchange (Exchange Algebra) among agents. Exchange algebra gives bottom-up reconstruction of SNA (System of National Accountings). SLD provides the concept of indirect control of socio-economic systems to manage structural change and its stability. We also compare agent-based simulation with gaming simulation and investigate the epistemological foundation of agent-based modeling.