Visar resultat för..."Xu Hua Ling"

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Chapters provide basic introduction of TGF-ß signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-ß signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway;

This book shows how blockchain technology can transform the Internet, connecting global businesses in disruptive ways. It offers a comprehensive and multi-faceted examination of the potential of distributed ledger technology (DLT) from a new perspective: as an enabler of the Internet of Value (IoV).

This book shows how blockchain technology can transform the Internet, connecting global businesses in disruptive ways. It offers a comprehensive and multi-faceted examination of the potential of distributed ledger technology (DLT) from a new perspective: as an enabler of the Internet of Value (IoV).

Focuses on the combination of theory and experiment to study the shut-in problem in solid-state batteries.

This book focuses on modeling the anomalous diffusion phenomena, being ubiquitous in the natural world. Both the microscopic models (stochastic processes) and macroscopic models (partial differential equations) have been built up. The relationships between the two kinds of models are clarified, and based on these models, some statistical observables are analyzed. From statistics to mathematics, the built models show their power with their associated applications.This book is important for students to develop basic skills to be able to succeed in their future research. In addition to introducing the related models or methods, it also provides the corresponding applications and simulation results, which will attract more readers ranging from mathematicians to physicists or chemists, to name a few.

This book explores the latest theories, methods, and applications of consensus modeling. It proposes a variety of consensus modeling methods for different decision-making contexts, including conflict risk mitigation in group decision-making, integration with the failure mode and effects analysis technique, consideration of over-adjustment and flexible consensus, social network large-group decision-making environments involving multiple consensus costs, and multi-agent collaborative decision-making with consideration of trade-offs between revenue and reputation. In addition, this book discusses the application and implementation process of the proposed consensus modeling techniques in real-world decision-making, including collecting decision data, organizing decision-making groups, controlling the decision-making process, and evaluating the results.We encourage researchers, academics, students, business managers, and policy makers engaged in a variety of real-world decisions characterized by group decision-making (e.g., emergency decisions, public affairs decisions, and major corporate decisions) to pay attention to the proposals presented in the book. This book systematically describes the latest theories, methods, and applications of consensus modeling with a view to providing practical methodological support for corporate decision-making, governmental decision-making, and so on. Special emphasis is placed on the fact that this book can provide students, especially graduate students, with a comprehensive perspective on the study of consensus modeling. For businesses and governments, this book provides methodological support for how to merge inputs from multiple parties to obtain a majority-approved consensus solution (at minimal group cost) and ultimately develop group wisdom.

The 2017 2nd International Conference on Electromechanical Control Technology and Transportation (ICECTT 2017) was held on January 14–15, 2017 in Zhuhai, China. ICECTT 2017 brought together academics and industrial experts in the field of electromechanical control technology and transportation to a common forum. The primary goal of the conference was to promote research and developmental activities in electromechanical control technology and transportation. Another goal was to promote exchange of scientific information between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year thus making it an ideal platform for people to share views and experiences in electromechanical control technology and transportation and related areas.

The International Symposium on Dynamics of Vehicles on Roads and Tracks is the leading international gathering of scientists and engineers from academia and industry in the field of ground vehicle dynamics to present and exchange their latest innovations and breakthroughs. Established in Vienna in 1977, the International Association of Vehicle System Dynamics (IAVSD) has since held its biennial symposia throughout Europe and in the USA, Canada, Japan, South Africa and China. The main objectives of IAVSD are to promote the development of the science of vehicle dynamics and to encourage engineering applications of this field of science, to inform scientists and engineers on the current state-of-the-art in the field of vehicle dynamics and to broaden contacts among persons and organisations of the various countries engaged in scientific research and development in the field of vehicle dynamics and related areas.IAVSD 2017, the 25th Symposium of the International Association of Vehicle System Dynamics was hosted by the Centre for Railway Engineering at Central Queensland University, Rockhampton, Australia in August 2017. The symposium focused on the following topics related to road and rail vehicles and trains: dynamics and stability; vibration and comfort; suspension; steering; traction and braking; active safety systems; advanced driver assistance systems; autonomous road and rail vehicles; adhesion and friction; wheel-rail contact; tyre-road interaction; aerodynamics and crosswind; pantograph-catenary dynamics; modelling and simulation; driver-vehicle interaction; field and laboratory testing; vehicle control and mechatronics; performance and optimization; instrumentation and condition monitoring; and environmental considerations. Providing a comprehensive review of the latest innovative developments and practical applications in road and rail vehicle dynamics, the 213 papers now published in these proceedings will contribute greatly to a better understanding of related problems and will serve as a reference for researchers and engineers active in this specialised field. Volume 2 contains 135 papers under the subject heading Rail.