SpringerBriefs in Cancer Research – serie
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9 produkter
MHC Class I Antigens In Malignant Cells
Immune Escape And Response To Immunotherapy
Av Natalia Aptsiauri, Angel Miguel Garcia-Lora m. fl.
Häftad, 2013
566 kr
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Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different …
EBNA1 and Epstein-Barr Virus Associated Tumours
Häftad, 2013
566 kr
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This SpringerBrief is comprehensive account of the functions and effects of the Epstein-Barr virus (EBV) EBNA1 protein that relate to EBV-associated cancers and evidence for EBNA1 contributions to these cancers. EBNA1 was the first EBV protein detected and the most critical for EBV latent …
Obesity and Breast Cancer
The Role of Dysregulated Estrogen Metabolism
Av Kristy A. Brown, Evan R. Simpson
Häftad, 2013
566 kr
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Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are …
New Insights on Vitamin C and Cancer
Av Michael J. Gonzalez, Jorge R. Miranda-Massari
Häftad, 2014
678 kr
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Research on vitamin C and its effects on cancer is growing in popularity around the world as positive research continues to accumulate building a stronger case for its effectiveness. This concise SpringerBrief on Vitamin C and Cancer presents the latest findings on how vitamin C induces apoptosis. …
SCF and APC E3 Ubiquitin Ligases in Tumorigenesis
Av Hiroyuki Inuzuka, Wenyi Wei
Häftad, 2014
566 kr
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This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thought to be the major driving forces governing proper …
Quick Guide to Cancer Epidemiology
Av Paolo Boffetta, Stefania Boccia m. fl.
Häftad, 2014
678 kr
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A Quick Guide to Cancer Epidemiology is an ideal addition to Springer Briefs in Cancer Research. The Brief provides core concepts in cancer epidemiology and also gives a snapshot of the epidemiology of seventeen human cancers. The Brief aims to provide-with quantitative focus-estimates of the …
miRNAs and Target Genes in Breast Cancer Metastasis
Av Seema Sethi
Häftad, 2014
566 kr
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This SpringerBrief gives the latest research on the role of miRNAs in breast cancer metastasis. MicroRNAs (miRNAs) are recently described small endogenous noncoding RNAs implicated in the posttranscriptional control of gene expression. These tiny molecules are involved in developmental, physiologic …
Hepatocellular Carcinoma
Cellular and Molecular Mechanisms and Novel Therapeutic Strategies
Av Rajagopal N. Aravalli, Clifford J. Steer
Häftad, 2014
566 kr
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This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular …
Systems Biology of Tumor Physiology
Rethinking the Past, Defining the Future
Häftad, 2015
566 kr
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This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor microenvironment …