- Häftad (Paperback)
- Antal sidor
- Academic Press
- C.Perin, Emerson / W.Miller, Leslie / Taylor, Doris / T.Willerson, James
- 273 x 215 x 25 mm
- Antal komponenter
- 1700 g
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Stem Cell and Gene Therapy for Cardiovascular Disease
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As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials.
Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic.
- Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials
- Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis
- Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI
- Covers the prevailing opinions on how to harness the body's natural repair mechanisms
- Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals
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"... accomplishes a thorough overview of the topic that is appropriate for the everyday cardiovascular practitioner, but it also can be used a stepping stone for anyone wishing to get deeply involved in the field. It is likely more comprehensive that any book currently on the market. Score: 80 - 3 Stars" --Doody's
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Introduction: Regenerative Medicine for Cardiovascular Disease Chapter 1: Introduction and Overview of Stem Cells Chapter 2: Mechanistic Insights from Pathologic Perspective Chapter 3: Large Animal Models to Study Stem Cell Therapy Chapter 4. Evolution of understanding of the mechanisms of repair Chapter 5: Impact of Age on Stem Cell Function Chapter 6: Bone Marrow Mononuclear Cells Chapter 7: Chronic Limb Ischemia Chapter 8: Chronic/Refractory Angina Chapter 9: Acute Myocardial Infarction A. European Experience B. US Experience Chapter 10: Chronic Ischemic Heart Failure Chapter 11: Adipose Tissue Chapter 12: Overview of MSCs Chapter 13: Allogeneic vs Autologous Source: Comparative Effects Chapter 14: Use of MSCs for AMI Chapter 15: Combined Cell Strategies Chapter 16: Heart Failure Chapter 17: C-Kit+ cells Chapter 18: Cardiospheres Chapter 19: Umbilical Cord, Placenta, Endometrium Chapter 20: Genetic Engineering of Fibroblasts to Cardiomyocytes Chapter 21: Transformation to inducible Pleuripotent Stem Cells Chapter 22: Transformation to MAPC's Chapter 23. Transcoronary and Endocardial Chapter 24. Retrograde and Epicardial Chapter 25. Epicardial Patch Chapter 26. Matrix Scaffolds Chapter 27. Matrix plus cells Chapter 28. Biomaterial: Alginate Chapter 29: Organogenesis Chapter 30: Pre-clinical Identification of target genes Chapter 31: SERCA-2a gene for recovery of inotropic function Chapter 32: SDF-1 Gene for Heart Failure Non-Inotropic Mechanisms Chapter 33: Gene Therapy for Angiogenesis: Chronic Limb Ischemia Chapter 34: Stem Cells Target Gene Transfected Stem Cells Chapter 35: CCTRN: Past, Present, and Vision for the Future Chapter 36: Signature of Responders-lessons from Bio-Repository Chapter 37: Adjunctive therapy with LVADs for Recovery Chapter 38: Trials in Non-Ischemic Heart Failure Chapter 39: Enhancing Stem Cell Homing for Tissue Repair Chapter 40: Stroke: Pre-Clinical and Clinical Trial Data