Lantibiotics as Alternative Therapeutics

Dr. Sanket Joshi is currently a Professor at the Amity Institute of Microbial Technology, Amity University, Rajasthan, India. He has academic teaching and research experience of about 16 years, and industrial R&D experience of about 4 years in India and Oman. While working in Indian pharma companies, he undertook several turnkey projects. His current research interests encompass energy (In-situ/ex-situ microbial enhanced light/heavy oil recovery; chemical enhanced oil Recovery; biofuels), microbial products (biosurfactants, biopolymers, R&D and scale-up), and environmental bioremediation (crude oil pollution; analysis, mitigation and control of souring by Sulfate reducing bacteria; HPAM contaminated sites). He has about 125 scientific publications in international journals, book chapters, and conference proceedings, and two books to his credit. He is an Academic/Associate Editor for: Frontiers in Microbiology, PeerJ, Ecotoxicology (Springer), Petroleum Science and Technology (Springer), Biotech (Springer), and Open Biotechnology Journal; guest editor for Frontiers in Microbiology, Sustainability, Scientifica, and Open Biotechnology Journal. Dr. Kar is a Scientist at Technische Universität Berlin, Institute for Chemistry, Germany. He works in the Bio-Molecular Modelling Group, on application of classical and quantum mechanical simulations in collaboration with experimental measurements to explore the mechanistic details in flavin-based bifurcating system. He previously worked as a Post-Doctoral Fellow in Fritz Haber Center for Molecular Dynamics Research, in group of Dr. Igor Schapiro, Hebrew University of Jerusalem, Israel. [Apr 2017 – Jun 2020], and as a Project Assistant in Department of Biophysics, Bose Institute, Bose Institute, Kolkata. [July 2011 – Jan 2012]. He received various awards/scholarships. He has more than 55 publications in journals of international reputes, conferences, and book chapters, to his credit. Dibyajit Lahiri is Associate Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. His research interest is precisely on biofilm isolated from human prosthesis and its inhibition by various novel phyto and nano compounds. He is keen to explore the molecular mechanism behind the removal of biofilm by natural compounds. His research arena also encompasses computational drug development by using of bioinformatic. His work is regularly being presented and appreciated before a number of experts of National and International repute. He has more than 100 publications. Dr. Lahiri has edited 5 books. He is also in the role of associate editors of various journals of international reputes. Dr. Moupriya Nag is an Associate Professor in the Department of Biotechnology at UEM, Kolkata. Her research interests include single molecule biophysics, particularly protein unfolding/refolding and protein aggregation kinetics. She has expertise in biophysical chemistry, photochemistry, and single molecule spectroscopy, and has worked on protein-ligand interactions and in-vitro detection of metal ions. Her postdoctoral work explored peptide aggregation kinetics related to neurodegenerative diseases. Currently, her research focuses on functional amyloids in bacteria and their role in biofilm formation.

• 1. Genetics of the development of antibiotic and multi-drug resistance2. Antimicrobial peptides and the potent mechanism of action3. Lantibiotics and Gene regulation 4. Biosynthesis of Lantibiotics5. Optimizations in the productions of Lantibiotics and Scale-Up6. Analytical Techniques in Identifying & Purifying the proteins7. Development of Recombinant Lantibiotics and their Potent Uses8. Mechanism of Action of the Lantibiotics on the Multi-Drug Resistant Organism9. Mechanism of inhibiting Biofilm associated Chronic Infections by Lantibiotics10. Lantibiotics & Its Role in Food Preservation11. In-Silico studies of the Interaction of Lantibiotics with Virulent Proteins12. Insights at the atomistic resolution of Lantibiotics using Multiscale Simulations13. Case studies: Applications of such novel drugs14. Recent updates in understanding of molecular genetics of lantibiotics production15. In silico molecular modelling approach for better designing and applications16. Marine microbes as a potential source of novel drugs17. Combinations of nano-bio molecules as next generation antimicrobial agents