Although a number of molecules are used today to treat cancer, the miracle molecule that could prevent cancer has not yet been identified. But could it be found among the medicinal and food plants traditionally used to prevent cancer? This work focuses in particular on the chemistry, pharmacology, and molecular pathways of the active ingredients of more than 200 medicinal and food plants of the world traditionally used for the prevention of cancer. For each plant, the Latin name, synonyms, common name, medicinal uses, pharmacology, active ingredients, toxicity, and commentaries that discuss the clinical potential are provided. Chemical structures are provided as well as selected references.Key FeaturesA phylogenetic presentation of over 200 medicinal plants and the pharmacological rationales for their uses for the prevention of cancer.Discusses the medicinal uses, and potential candidates for the prevention of cancer.Introduces the molecular mechanism of natural products on the pathophysiology of cancer development.Contains a selection of chemical structures, botanical plates, and bibliographic references.Highlights the medicinal plants globally that can afford people to live longer and more healthier lives.