Daniel A. Casciano - Böcker

Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessmentnanotoxicity assessment by gene expression analysisin vivo and in vitro models for nanotoxicity testingmechanisms of nanotoxicitypharmakokinetics of nanomaterialsnanotoxicity of foods including food processing, food packaging and food safetynanotoxicity of drugs including drug development and drug deliverynanotoxicity of cosmetics and consumer productshealth and environmental impact of nanotoxicitysafety evaluation of nanomaterialsregulatory impact of nanomaterialsNanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.

Frontiers in Toxicology is the essential tool for toxicologists and pharmacologists working in academia, industry and regulatory bodies looking to stay at the forefront of three of the most important and upcoming areas of toxicology: toxicogenomics, hepatotoxicity and nanotoxicity. Insights from leading researchers into the current trends and future directions of research are presented in three volumes.  Each volume provides details on recent scientific discoveries, rules of best practice and addresses how national and international regulatory agencies will deal with the safety issues associated with toxicology.  Many of the chapters are written by authors working for the US Food and Drug Administration, including Dr. Saura C. Sahu himself.Titles included in the three volume set:Nanotoxicity: From In Vivo and In Vitro Models to Health Risks  - August 2009Toxicogenomics: A Powerful Tool for Toxicity Assessment - October 2008Hepatotoxicity: From Genomics to In Vitro and In Vivo Models - December 2007Each volume is also available to purchase individually.