Elena L. Paley - Böcker

Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer's and other neurodegenerative conditions, cancer and inflammatory disorders, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes. Enables biochemists, molecular biologists and disease researchers to advance disease prevention, laboratory testing, and treatment pathways for protein biosynthesis interference related disorders Examines the biochemical and molecular basis of protein biosynthesis interference in neurodegenerative disorders, cancer and inflammatory conditions, among other diseases Analyzes tryptamine, biogenic amines, and aminoacyl-tRNA synthetases dynamics in protein translation and possible treatment pathways regulating protein biosynthesis

Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer's disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body.

Explores microbial metabolic pathways in the human body and implications for disease Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways Considers a variety of diseases and disorders, such as Alzheimer's disease, metabolic syndromes, Crohn's disease and Covid-19 Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold's reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book.

Addresses the emerging hypothesis of a dysfunctional microbiome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions Covers dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea Presents the conceptual model of food and gut microbial tryptamine vagus nerve circuit Covers human health and intellectual abilities in the context of both the human genome and the human microbiome

Microbial Tryptamine as a Causative Cofactor of Incurable Cell Death Diseases of Unknown Etiology: The Cost of Related Healthcare in the US and Worldwide investigates microbial tryptamine and its role in a range of diseases, such as Alzheimer’s disease and Parkinson’s disease, while also examining the economic burden of these conditions on global healthcare systems. The book begins with an examination of microbial tryptamine’s significance across neurodegenerative diseases, cancers, and gastrointestinal conditions. It covers the implications of tryptamine in cell and organ transplantation, as well as the roles of diet and environment in tryptamine-induced disease progression. Additionally, the latest advances in treatment and prevention are considered. It then provides a critical analysis of expenditure on diseases related to tryptamine-induced cell toxicity and neurodegeneration, alongside an evaluation of current funding and market analysis. Following this, the author delves into research-related issues that may hinder biomedical progress, such as competition, plagiarism, and retractions of funded peer-reviewed articles. Collaboration between researchers and medical doctors is also examined. The book concludes with the author’s own personal narrative and recommendations, emphasizing the need for open discussions to drive urgent changes in biomedical research funding and review processes.Explores microbial tryptamine in diseases like cancer, Alzheimer's disease, and Parkinson’s disease, and its effects on the gut microbiomeAnalyzes research funding related to tryptamine-induced diseases of unknown etiology, advocating for the need to invest in further treatment and laboratory diagnostic testsAddresses systemic issues in biomedical research and the need to improve scientific integrityExplores healthcare expenditures linked to tryptamine-associated pathologies