Richard E. Passingham – författare

Brain imaging has revolutionised the field of Psychology - once more concerned with IQ tests, reaction times and questionnaires. Most Psychology departments now have access to an MRI scanner - some have even renamed themselves as departments of cognitive neuroscience. Yet brain imaging can be a minefield, whichever discipline you approach it from. If you are a psychologist, you will have been taught how to do behavioural experiments, but may know little neuroanatomy or neurophysiology. If you are a neurologist or psychiatrist, then you may know the neuroanatomy and neurophysiology, but not know how to carry out experiments on mental phenomena. This is a practical guide to brain imaging, showing how it can advance a true neuroscience of human cognition. It is accessible to those starting out in imaging, whilst also informative for those who have already acquired some expertise. At the heart of the book are 6 main chapters, focusing on - the signal, experimental methods, anatomy, functional specialisation, functional systems, and other methods.For students and researchers in psychology and neuroscience, this is the essential companion when embarking on brain imaging studies.

The prefrontal cortex makes up almost a quarter of the human brain, and it expanded dramatically during primate evolution. The Neurobiology of the Prefrontal Cortex presents a new theory about its fundamental function. In this important new book, the authors argue that primate-specific parts of the prefrontal cortex evolved to reduce errors in foraging choices, so that particular ancestors of modern humans could overcome periodic food shortages. These developments laid the foundation for working out problems in our imagination, which resulted in the insights that allow humans to avoid errors entirely, at least at times.In the book, the authors detail which parts of the prefrontal cortex evolved exclusively in primates, how its connections explain why the prefrontal cortex alone can perform its function, and why other parts of the brain cannot do what the prefrontal cortex does. Based on an analysis of its evolutionary history, the book uses evidence from lesion, imaging, and cell-recording experiments to argue that the primate prefrontal cortex generates goals from a current behavioural context and that it can do so on the basis of single events. As a result, the prefrontal cortex uses the attentive control of behaviour to augment an older general-purpose learning system, one that evolved very early in the history of animals. This older system learns slowly and cumulatively over many experiences based on reinforcement. The authors argue that a new learning system evolved in primates at a particular time and place in their history, that it did so to decrease the errors inherent in the older learning system, and that severe volatility of food resources provided the driving force for these developments.Written by two leading brain scientists, The Neurobiology of the Prefrontal Cortex is an important contribution to our understanding of the evolution and functioning of the human brain.

In the late 1960s and early 1970s David Marr produced three astonishing papers in which he gave a detailed account of how the fine structure and known cell types of the cerebellum, hippocampus and neocortex perform the functions that they do. Marr went on to become one of the main founders of Computational Neuroscience. In his classic work 'Vision' he distinguished between the computational, algorithmic, and implementational levels, and the three early theories concerned implementation. However, they were produced when Neuroscience was in its infancy.Now that so much more is known, it is timely to revisit these early theories to see to what extent they are still valid and what needs to be altered to produce viable theories that stand up to current evidence. This book brings together some of the most distinguished scientists in their fields to evaluate Marr's legacy. After a general introduction there are three chapters on the cerebellum, three on the hippocampus and two on the neocortex. The book ends with an appreciation of the life of David Marr by Lucia Vaina.

A successor to the acclaimed 'Neurobiology of the Prefrontal Cortex', 'Understanding the Prefrontal Cortex' presents a careful study of the anatomical connections in this brain region, showing how each area and subarea of the brain has a unique pattern of connections, and exploring the transformation that this area performs - from its inputs to it outputs. The book starts with two chapters of foundational material, before considering five subdivisions of the prefrontal cortex, and looking at the transformation that each one performs. Next it considers how the prefrontal cortex interacts with the rest of the brain, including not only cortical areas but also subcortical areas such as the basal ganglia and cerebellum. The book ends with a final section in which these principles are applied to the human brain. It starts by discussing the expansion of the prefrontal cortex during human evolution. It then considers how the human brain has co-opted mechanisms that existed in our primate ancestors, and by providing new inputs had extended them so as to support reasoning, remembering events from the distant past and imagining events in the distant future, the sense of self, language, the ability to understand the mental states of others, and the ability to cooperate and learn social and moral rules.Written by a leading brain scientist, the book will be an important and influential contribution to the neuroscience literature.