Timothy R. Rebbeck – författare
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3 produkter
3 produkter
939 kr
Skickas inom 10-15 vardagar
Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, genetic counseling and testing of high risk patients, and screening and prevention options for individuals at risk of hereditary breast cancer. Addressing every essential aspect of hereditary breast cancer, thissource offers comprehensive analyses of hereditary breast cancer-associated syndromes, low penetrance genes, and hereditary breast cancer associated with mutations in the BRCA1 and BRCA2 genes.
2 831 kr
Skickas inom 10-15 vardagar
Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, genetic counseling and testing of high risk patients, and screening and prevention options for individuals at risk of hereditary breast cancer. Addressing every essential aspect of hereditary breast cancer, thissource offers comprehensive analyses of hereditary breast cancer-associated syndromes, low penetrance genes, and hereditary breast cancer associated with mutations in the BRCA1 and BRCA2 genes.
2 478 kr
Skickas inom 10-15 vardagar
This volume comprises the investigation of factors that may predict the response to treatment, outcome, and survival by exploring:• design considerations in molecular epidemiology, including:case-onlyfamily-basedapproaches for evaluation of genetic susceptibility to exposure and addiction pharmacogeneticsincorporation of biomarkers in clinical trials• measurement issues in molecular epidemiology, includingDNA biosampling methodsprinciples for high-quality genotypinghaplotypesbiomarkers of exposure and effectexposure assessment• methods of statistical inference used in molecular epidemiology, includinggene-gene and gene-environment interaction analysisnovel high-dimensional analysis approachespathway-based analysis methodshaplotype methods, dealing with race and ethnicityrisk modelsa discussion of reporting and interpreting results• A specific discussion and synopsis of these methods provides concrete examples drawn from primary research in cancerCovering design considerations, measurement issues, and methods of statistical inference, and filled with scientific tables, equations, and pictures, Molecular Epidemiology: Applications in Cancer and Other Human Diseases presents a solid, single-source foundation for conducting and interpreting molecular epidemiological studies.