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New interventions are needed to reduce the burden of vector-borne diseases like malaria and dengue, which are among the most serious and prevalent infectious diseases worldwide. The release of genetically modified (GM) mosquitoes may offer an alternative strategy to do so while circumventing the pitfalls of current vector control methods. Contemporary methodologies are stalling because of drug resistance, absence of vaccines and inadequate mosquito control techniques. GM mosquitoes have been developed that are resistant to pathogen infection and transmission, but the public-health and environmental consequences of releasing such insects are unclear, mainly because of a lack of knowledge of the ecology and population biology of mosquitoes. This book is the reflection of a workshop, held in June 2002, that addressed these issues. Experts on mosquito ecology met to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors.This volume should stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.
1 590 kr
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New interventions are needed to reduce the burden of vector-borne diseases like malaria and dengue, which are among the most serious and prevalent infectious diseases worldwide. The release of genetically modified (GM) mosquitoes may offer an alternative strategy to do so while circumventing the pitfalls of current vector control methods. Contemporary methodologies are stalling because of drug resistance, absence of vaccines and inadequate mosquito control techniques. GM mosquitoes have been developed that are resistant to pathogen infection and transmission, but the public-health and environmental consequences of releasing such insects are unclear, mainly because of a lack of knowledge of the ecology and population biology of mosquitoes. This book is the reflection of a workshop, held in June 2002, that addressed these issues. Experts on mosquito ecology met to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors.This volume should stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.
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The workshop “Environmental Change and Malaria Risk: Global and Local Implications” was held to conclude a 5-year collaborative research project on environmental change and malaria risk, with field research in Kenya and Brazil. It was fitting that such a large group of specialists was able to attend the workshop and contribute with a chapter in which the predicted environmental changes were viewed from different angles. We would like to thank the Netherlands Foundation for the Advancement of Tropical Research (WOTRO) and the National Programme for Research on Climate Change and Air Quality (NOP) for having funded our work so generously. Wageningen UR – Frontis is thanked for having arranged the workshop and for its financial contribution. We would especially like to thank Petra van Boetzelaer for having assisted with the logistics of the workshop, and Paulien van Vredendaal for having spent many hours in the type editing of the chapters, making publication of this book possible. The editors, Willem Takken Pim Martens Rob Bogers Wageningen, March 2005 Colour pages Chapter 2. Pim Martens and Chris Thomas; Figures 2 and 3 Figure 2. MARA/ARMA index of climatic suitability for P. falciparum transmission in four consecutive months Figure 3. Number of consecutive months with a MARA/ARMA index of climatic suitability for P. falciparum transmission of p ?0. 9 in each month Colour pages Chapter 5. M. B. Hoshen and A. P.