Advances in Brain Tumor Therapy

Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at Vivekanand Global University, where he is involved in teaching and interdisciplinary research. His academic interests span nano-formulation, artificial intelligence, machine learning, big data analytics, Internet of Things (IoT), blockchain, cancer biology, and neuroscience.He has contributed to scholarly literature through a book published with IOP Publishing, five book chapters with River Publishers, and 28 review articles in peer-reviewed journals, including publications in Biochimica et Biophysica Acta (BBA) – Reviews on Cancer.He has also authored and edited books with publishers such as Elsevier, CRC Press, and Wiley. His work focuses on the integration of pharmaceutical sciences with emerging technologies, with an emphasis on interdisciplinary research and healthcare-related applications.Prof. (Dr.) Rajwinder Kaur is the Assistant Dean of Pharm D (Academics) at Chitkara College of Pharmacy, Chitkara University, Punjab, India. With sixteen years of experience in teaching and research, she has held positions such as DST Women Scientist (WOS-A) at Punjab University, Chandigarh, and received prestigious fellowships like the CSIR-SRF and UGC-MRP. Dr. Kaur was awarded the "Dr. Harpal Singh Buttar and Harinder Kaur Buttar Young Scientist Award in Pharmaceutical Sciences for Rural Women" in 2013 and the Young Scientist Award "Women in Pharmaceutical Sciences" in 2023. Her research focuses on computational drug design, synthesis of fused-heterocyclic compounds, nanomedicine, and AI, particularly in inflammation, asthma, and neurological disorders. Dr. Kaur has published over 50 papers and 10 book chapters, and has edited a book. She is a senior member of the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and a life member of the Indian Pharmacy Graduate Association (IPGA). Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.Dr. Niraj Kumar Jha is an Assistant Professor of Biotechnology at Galgotias University, India, with prior research affiliations at the Centre for Research Impact & Outcome (CRIO), Chitkara University, and Sharda University. His research portfolio encompasses over 200 peer-reviewed articles and scholarly reviews, along with an edited volume published by Springer, reflecting sustained contributions to biomedical research and translational science. According to Scopus metrics, Dr. Jha’s publications have garnered more than 10,000 citations, with an H-index exceeding 50, underscoring the broad impact and visibility of his work within the global scientific community. He is an elected Member of the Royal Society of Biology (MRSB), London, and has been recognized among the World’s Top 2% Scientists in rankings compiled by Elsevier in collaboration with Stanford University. Dr. Jha actively contributes to scientific publishing and peer review as an associate editor for the Journal of Alzheimer’s Disease (IOS Press) and IET Nanobiotechnology (Wiley) and serves on the editorial boards of several international journals, including Scientific Reports. His research is centered on elucidating the molecular and cellular mechanisms underlying complex diseases such as neurodegenerative disorders, cancer, and cardiovascular pathologies. His work particularly emphasizes the modulation of key signaling pathways and explores the therapeutic potential of natural products, phytochemicals, and synthetic small molecules in disease intervention.

• 1. Introduction to Brain Tumors2. Molecular Pathogenesis of Brain Tumors3. Pharmacokinetics and Pharmacodynamics in Brain Tumor Treatment4. Conventional Chemotherapeutic Approaches for Brain Tumor Treatment5. Targeted Molecular Therapies for Brain Tumor6. Immunotherapy and Brain Tumors7. Epigenetic Therapies for Brain Tumor8. Nanotechnology and Drug Delivery Systems for Brain Tumor9. Stem Cells in Brain Tumor Therapy10. Harnessing Oxidative Stress: Novel Therapeutics in Pediatric Brain Cancer11. Advanced Imaging Techniques in Brain Tumor Diagnosis and Surgery12. Combination Therapies for Brain Therapy: Synergistic Approaches13. Decoding MGMT: Biochemistry, Drug Resistance, and Diagnostic Innovations14. Molecular Mechanisms of Drug Resistance in Brain Therapy15. Personalized Medicine in Brain Tumors16. Innovations and Obstacles in Pediatric Brain Cancer Therapy17. Clinical Trials and Regulatory Aspects for Brain Tumor Treatment18. Future Directions in Brain Tumor Therapy19. Case Studies and Real-World Applications