Mitochondria-targeted Drug Delivery Strategies for Cancer Therapy

Arun Kumar Singh holds an M.Pharm in Pharmaceutics from Galgotias University, India, and serves as an Assistant Professor in the Department of Pharmacy at Vivekanand Global University. He is actively engaged in teaching and interdisciplinary research spanning nano-formulation, artificial intelligence, machine learning, big data analytics, IoT, blockchain, cancer biology, and neuroscience.Mr. Singh has made substantial scholarly contributions, authoring one book with IOP Publishing, five book chapters with River Publishers, and 28 review articles in reputed journals, including high-impact publications in Biochimica et Biophysica Acta (BBA) – Reviews on Cancer. In addition, he has authored and edited 58 books with leading publishers such as Elsevier, CRC Press, and Wiley. Known for his research acumen and leadership, Mr. Singh is committed to advancing pharmaceutical sciences through innovation and interdisciplinary collaboration, with a focus on impactful healthcare solutions.Dr. Neeraj Mishra is working as Professor and Head, Department of Pharmaceutics in Amity Institute of Pharmacy, Gwalior since July 2019. He has around twenty years of teaching and research experience. He has more than 140 publications of International and National repute in recent concepts of novel drug delivery systems, localized drug delivery, targeted and controlled drug delivery of nanocarriers for the treatment of breast, colon cancer, and neurodegenerative disorders. Dr. Mishra has supervised 30 M Pharm and 3 PhD students. Dr. Mishra more than 4500 citations with h- index 37. The total cumulative Impact Factor of his published papers is more than 500 (as per SCOPUS). He has also written 25 Books and 45 book chapters in Elsevier, Bentham, Springer and Wiley Publication etc. He has also been granted 3 international patents and 2 Indian patents. Dr. Mishra is recipient of “Distinguished Professor Award” 2019 from DST-NSTMIS, SPAICS, Indore, and M.P. in September 2019. Dr. Mishra has also received the “Outstanding Scientist Award '' 2020, 6th International Scientist Awards on Engineering, Science, and Medicine, 20-21 June 2020, Chennai, India. Dr. Mishra has received the “Distinguished Professor Award '' 2021 from Indian Pharmaceutical Association, MP State Branch, Indore. Dr Mishra has received Best Academician Award in the Indian Pharmacy Graduate Association, M.P. State International Conference held on 06th May 2023 at DAVV Auditorium, Indore, India. Recently, honored to be in World Top 2% Scientists by prestigious Stanford University, CA, USA and Elsevier in 2025. Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.Dr. Anoop Kumar is an Assistant Professor in the Department of Pharmacology at Delhi Pharmaceutical Sciences & Research University (DPSRU), India. With a distinguished career, he has previously served as an Assistant Professor and Head at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, and as Head and Associate Professor at ISF College of Pharmacy, Moga, Punjab. Dr. Kumar has also held research positions at Sun Pharmaceutical Industries Limited and Translational Health Science Institute (THSTI). He earned his Ph.D. from Birla Institute of Technology, Mesra, Ranchi, as a DST INSPIRE Fellow. He is an Associate Editor for Health Sciences Review and Acta Neurologica Scandinavica. His research focuses on drug repurposing, clinical trial meta-analysis, pharmacoeconomics, and pharmacovigilance. Dr. Gautam Sethi is a tenured Associate Professor in the Department of Pharmacology at the Yong Loo Lin School of Medicine, National University of Singapore. His research focuses on elucidating the molecular mechanisms underlying cancer initiation and progression, particularly the activation of oncogenic transcription factors by carcinogens and inflammatory agents, and the identification of novel therapeutic inhibitors. Dr. Sethi has made substantial and direct scholarly contributions to the fields of gut microbiota, cancer pathophysiology, and host–microbiome interactions, with particular emphasis on immunotherapy, tumor microenvironment modulation, metabolic signaling, and therapy response prediction. He has authored numerous peer‑reviewed research and review articles in high‑impact journals, received multiple international awards, and serves on the editorial boards of more than 15 international journals.

• 1. Introduction of nanotechnology: basic concept and properties2. Basics of cancer biology, and role of nanotechnology in cancer treatment3. Nanoparticle-Mediated Drug Delivery in Cancer Therapy: Addressing Drug Resistance Challenges4. Advancing Targeted Drug Delivery in Malignancy: Nanoengineering Strategies for Enhanced Efficacy5. Mitochondria in Cancer: Functions, Dysfunction, and Therapeutic Targets6. Introduction to mitochondria-targeted Drug Delivery in cancer7. Mitochondria-Targeted Drug Delivery Strategies for Cancer Treatment8. Mitochondria-Targeted Liposomes in Cancer Therapy9. Mitochondrial-Targeted Photosensitizers Nanoparticles in Photodynamic Therapy10. Role of Mitochondria-Penetrating Peptides in Cancer Therapeutics11. Modulating Mitochondrial Reactive Oxygen Species in Cancer Therapy through Nanomaterials12. Polymeric Nanoparticles for Mitochondria Targeting Mediated Robust Cancer Therapy13. Characterization of Mitochondria-Targeted, Nanoparticle-Based Drug-Delivery System14. Nanoplatforms: Overcoming Challenges in Mitochondrial Targeting for Effective Cancer Treatment15. Future directions and emerging trends of Mitochondria-Targeted Drug Delivery Strategies: Challenges and future prospects16. Clinical trials, toxicity studies and real-world applications of mitochondria-targeted drug delivery strategies