Gautam Sethi – författare

Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications.

It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention.

Phytochemicals in Cancer Therapy and Beyond explores the significant role of natural products in combating diseases, particularly cancer. The book emphasizes the mechanisms through which natural products operate in treatments, making it a comprehensive guide for understanding their therapeutic potential. Spanning 24 chapters, it delves into regular cancer treatments, challenges faced, and advancements in the field. Special focus is given to phytochemicals and their cellular mechanisms, molecular pathways in therapy, and innovative nano-scale delivery systems that enhance treatment efficacy.This book is an essential resource for oncology researchers, disease therapy experts, diabetes mellitus treatment professionals, cellular signaling scientists, and nanomaterial engineers, offering valuable insights into the clinical applications of phytochemical therapies.

This book serves as a critical resource that bridges the gap between burgeoning technology and its practical implementation. The book starts with an in-depth exploration of healthcare 5.0 principles, laying the foundation for the reader to understand the current shifts in healthcare paradigms. Then, it dives into the intricacies of generative models in healthcare, detailing how these algorithms work and the applications they serve. The book further delves into the subsets of generative machine learning and deep learning techniques in healthcare. As we move towards more complex applications, the book takes a turn to address the critical subject of interpretability and explainability in generative models, a topic that resonates profoundly given the life-critical nature of medical decisions. Finally, the book concludes with a robust discussion on the security and privacy concerns that accompany the deployment of GAI in real healthcare settings. By offering a multidimensional viewpoint—coupled with case studies, statistical analyses, and expert insights—the book ensures that the reader is left with a nuanced understanding of how GAI can be both a boon and a challenge in healthcare. As such, the proposed book serves as an indispensable resource for healthcare professionals, data scientists, researchers, and anyone invested in the future of healthcare and AI.

The book covers the various cell signaling pathways responsible for prostate cancer progression, conventional therapies used for prostate cancer treatment, new emerging therapeutics, and challenges in the treatment of cancer patients. It describes the different molecular pathways responsible for prostate cancer progression to improve readers'' knowledge about the role of signaling networks, and cellular and molecular aspects of prostate cancer progression. These topics include mechanisms responsible for prostate cancer malignancy with a focus on molecular pathways. It also discusses the current challenges in prostate cancer treatment such as drug resistance and immune evasion and introduces novel therapeutics such as gene therapy and nanotherapeutics for prostate cancer. 

This book is completely novel and unique and covers all aspects of prostate cancer progression and challenges in therapy while presenting solutions. Written by prestigious researchers around the world, this book will be interesting to researchers and practitioners, especially those working in urological cancers.