Senthilkumar Rajagopal – författare

Recent Advances in Targeting Inflammation: Ion Channels, GPCR Signaling Tools, Therapies, and Beyond delves into the multifaceted occurrences of inflammation across different systems, such as neuroinflammation and gastric inflammation. The book's main goal is to present the latest highlights, covering advancements in inflammation, investigational therapies, animal models, and biomarkers. These insights are crucial for better diagnosis, monitoring, and potential therapeutic options for patients suffering from both acute and chronic inflammation. This comprehensive work explores various topics, including ion channel regulation in inflammation, GPCR regulation, signaling pathways, and therapeutic approaches.It emphasizes the importance of understanding the role of ion channels, GPCR, and nutrition in managing inflammation effectively. Additionally, the book discusses the global impact of chronic inflammation on health outcomes, stressing the need for improved healthcare planning and strategies.Focuses on the development of multiple discipline approaches in inflammation and nutrition-related researchBrings together leading researchers in ion channels' regulation of inflammationPresents essential reference information for researchers in the areaProvides current developments in disease, making it a vital resource for students and industry professionals

This reference book discusses the role of nutrition in obsessive-compulsive disorders (OCD). It covers the investigational therapies in OCD, use of animal models, and biomarkers for better diagnosis, monitoring, and possible therapeutic options with nutrients for patients with OCD. This book highlights the role of probiotics, amino acids, vitamins, micronutrients, and salts in the management of OCD. It includes such topics as applications of computational modeling and nano-biotechnology in OCD, the effects of environmental pollutants, and the regulation of antidepressants in OCD.KEY FEATURESCovers emerging therapeutic and nutritional approaches for the treatment and management of OCDReviews the role of various micronutrients in OCDDiscusses the prenatal genetic diagnosis and application of computational modelling in OCDIncludes the nutritional and dietary roles in such neuropsychiatric disorders as depression and obsessive-compulsive disorder (OCD)Explores the application of nano-biotechnology in OCD This book is meant for researchers and professionals in the field of nutritional neuroscience and psychology

This reference book discusses the role of nutrition in obsessive-compulsive disorders (OCD). It covers the investigational therapies in OCD, use of animal models, and biomarkers for better diagnosis, monitoring, and possible therapeutic options with nutrients for patients with OCD. This book highlights the role of probiotics, amino acids, vitamins, micronutrients, and salts in the management of OCD. It includes such topics as applications of computational modeling and nano-biotechnology in OCD, the effects of environmental pollutants, and the regulation of antidepressants in OCD.KEY FEATURESCovers emerging therapeutic and nutritional approaches for the treatment and management of OCDReviews the role of various micronutrients in OCDDiscusses the prenatal genetic diagnosis and application of computational modelling in OCDIncludes the nutritional and dietary roles in such neuropsychiatric disorders as depression and obsessive-compulsive disorder (OCD)Explores the application of nano-biotechnology in OCD This book is meant for researchers and professionals in the field of nutritional neuroscience and psychology

This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.

This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable sourcefor beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.

This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities.

This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.

It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models.

This book provides the latest research on the role of nutrients in the prevention and treatment of neurological disorders. The book also defines the mechanistic effects of neuroprotective and psycho protective effects of natural food in repairing brain damage.