M. Mohamed Essa – författare

This reference book discusses the role of nutrition in obsessive-compulsive disorders (OCD). It covers the investigational therapies in OCD, use of animal models, and biomarkers for better diagnosis, monitoring, and possible therapeutic options with nutrients for patients with OCD. This book highlights the role of probiotics, amino acids, vitamins, micronutrients, and salts in the management of OCD. It includes such topics as applications of computational modeling and nano-biotechnology in OCD, the effects of environmental pollutants, and the regulation of antidepressants in OCD.

KEY FEATURES

This reference book discusses the role of nutrition in obsessive-compulsive disorders (OCD). It covers the investigational therapies in OCD, use of animal models, and biomarkers for better diagnosis, monitoring, and possible therapeutic options with nutrients for patients with OCD. This book highlights the role of probiotics, amino acids, vitamins, micronutrients, and salts in the management of OCD. It includes such topics as applications of computational modeling and nano-biotechnology in OCD, the effects of environmental pollutants, and the regulation of antidepressants in OCD.

KEY FEATURES

The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. 

The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. 

Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.

This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.