Molecular Pathogenesis of Virus Infections

Inbunden, Engelska, 2005

Del 64 i serien Society for General Microbiology Symposia

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Beskrivning

Virus and prion diseases remain a major public health threat, in both developed and developing countries. The worldwide HIV pandemic is but one example of a newly emerged virus disease; other potential threats come from exotic viruses such as SARS, Ebola and Hantaan viruses. Older human viruses such as influenza, papilloma, herpes and the hepatitis viruses still cause major health problems. Furthermore, as well as causing acute infections, some viruses may also establish persistent infections which can lead to the development of chronic diseases, including cancer. This symposium book covers central factors that influence the pathogenicity of virus and prion infections. Topics range from innate and adaptive immune responses and virus evasion of host defences to details of selected virus∆host interactions, including those involving dengue virus, HIV, influenza viruses, coronaviruses, hepatitis C virus, herpesviruses, papillomaviruses, African swine fever virus and poxviruses.

Produktinformation

Utgivningsdatum:2005-04-21
Mått:157 x 234 x 22 mm
Vikt:698 g
Format:Inbunden
Språk:Engelska
Serie:Society for General Microbiology Symposia
Antal sidor:358
Förlag:Cambridge University Press
ISBN:9780521832489

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Mer om författaren

Paul Digard is a Lecturer in Virology in the Department of Pathology at the University of Cambridge, UK. Anthony A. Nash is Professor of Veterinary Pathology in the Division of Veterinary Biomedical Sciences at the University of Edinburgh, UK. Richard. E. Randall is Professor of Molecular Virology in the School of Biology at the University of St Andrews, UK

Innehållsförteckning

Preface; 1. Adaptive immune responses J. L. Whitton; 2. T-cell responses and dengue haemorrhagic fever G. Screaton and J. Mongkolsapaya; 3. The immune response to human immunodeficiency virus type 1 (HIV-1) E. Turnbull and P. Borrow; 4. Persistent RNA virus infections C. M. Dixon, L. Breakwell, G. Barry and J. K. Fazakerley; 5. Exotic virus pathogenesis S. Nichol; 6. Molecular approaches to the pathogenesis of feline coronaviruses C. Dye and S. Siddell; 7. The transmissible spongiform encephalopathies J. C. Manson and R. M. Barron; 8. Influenza virus pathogenicity R. G. Webster, A. S. Lipatov and E. Hoffmann; 9. RNAi as an antiviral mechanism and therapeutic approach R. P. van Rij and R. Andino; 10. Neurons and host immunity conspire to maintain herpes simplex virus in a latent state M. L. Freeman, V. Decman and R. L. Hendricks; 11. Hepatitis C virus disruption of interferon signalling pathways and evasion of innate intracellular antiviral defences S. M. Lemon and K. Li; 12. Human papillomaviruses and their effects on cell cycle control and apoptosis L. Gray, C. Jolly and C. S. Herrington; 13. Intracellular antiviral defence mechanisms: the power of interferon-regulated restriction factors O. Haller, F. Weber and G. Kochs; 14. Poxvirus immune evasion A. Alcami; 15. Evasion of host defence systems by African swine fever virus L. K. Dixon; 16. Murid herpesvirus 4 as a model for gammaherpesvirus pathogenesis J. P. Stewart, D. Hughes, L. Roaden and B. Ebrahimi; Index.