Phospholipases in Health and Disease

Inbunden, Engelska, 2014

Del i serien Advances in Biochemistry in Health and Disease

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Beskrivning

Overall, this book discusses the diverse mechanisms of phospholipase mediated signal transduction in different pathophysiological conditions and raises the possibility of specific forms of phospholipases serving as novel targets for drug development.

Produktinformation

Utgivningsdatum:2014-03-14
Mått:155 x 235 x 22 mm
Vikt:734 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Biochemistry in Health and Disease
Antal sidor:410
Upplaga:2014
Förlag:Springer-Verlag New York Inc.
ISBN:9781493904631

Utforska kategorier

Innehållsförteckning

Phospholipases in Health and Disease.- Role of Phospholipases in Regulation of Cardiolipin Biosynthesis and Remodelling in the Heart and Mammalian Cells.- Role of Phospholipases and Oxidized Phospholipids in Inflammation.- Phospholipases in Cardiovascular Disease.- The Structures and Functions of Intracellular Phospholipase A1 Family Proteins.- Phospholipase A and Breast Cancer.- Pathophysiological Aspects of Lipoprotein Associated Phospholipase A2: A Brief Overview.- Phospholipase A2 Activity Exhibited by a Bacterial Virulence Protein that Enters and Operates within a Variety of Host Cells.- Expression and Role of Phospholipase A2 in Central Nervous System Injury and Disease.- Cytoplasmic Phospholipase A2 and Autotaxin Inhibitors as Potential Radiosensitizers.- Phospholipase A2 Enzymes: Potential Targets for Therapy.- The Role of Phospholipase C Isozymes in Cellular Homeostasis.- Phospholipase C in the Immune Cell.- Phosphoinositide-specific Phospholipase C Enzymes and Cognitive Development and Decline.- Where life begins: Sperm PLCz in mammalian egg activation and implications in male infertility.- Oocyte Activation and Phospholipase C zeta (PLCζ): Male Infertility and Implications for Therapeutic Intervention.- Phospholipase C Signaling in Heart Disease.- Activation of Phospholipase C in Cardiac Hypertrophy.- The Protective Effect of Phospholipase C From Cardiac Ischemia-Reperfusion Injury.- Role of Phospholipase C in Cardioprotection During Oxidative Stress.- Mammalian Phospholipase D: Structure, Regulation and Physiological Functions of Phospholipase D and its Link to Pathology.- Emerging Roles of Phospholipase D in Pathophysiological Signaling.- Alterations in Phospholipase D During the Development of Myocardial Disease.