Peter Diggle – författare

As an introduction to discrete mathematics, this text provides a straightforward overview of the range of mathematical techniques available to students. Assuming very little prior knowledge, and with the minimum of technical complication, it gives an account of the foundations of modern mathematics: logic; sets; relations and functions. It then develops these ideas in the context of three particular topics: combinatorics (the mathematics of counting); probability (the mathematics of chance) and graph theory (the mathematics of connections in networks).Worked examples and graded exercises are used throughout to develop ideas and concepts. The format of this book is such that it can be easily used as the basis for a complete modular course in discrete mathematics.

Time series analysis is one of several branches of statistics whose practical importance has increased with the availability of powerful computational tools. Methodology that was originally developed for specialized applications, for example in finance or geophysics, is now widely available within general statistical packages. The second edition of Time Series: A Biostatistical Introduction is an introductory account of time series analysis, written from the perspective of applied statisticians whose interests lie primarily in the biomedical and health sciences. This edition has a stronger focus on substantive applications, in which each statistical analysis is directed at a specific research question. Separate chapters cover simple descriptive methods of analysis, including time-plots, smoothing, the correlogram and the periodogram; theory of stationary random processes; discrete-time models for single series; continuous-time models for single series; generalized linear models for time series of counts; models for replicated series; spectral analysis, and bivariate time series.The book is unique in its focus on biomedical and health science applications, which has been strengthened in this second edition. Nevertheless, the methods described are more widely applicable. It should be useful to teachers and students on masters-level degree courses in statistics, biostatistics and epidemiology, and to biomedical and health scientists with a knowledge of statistical methods at undergraduate level. Throughout, examples based on real datasets show a close interplay between statistical method and substantive science. This book will also describe the implementation of the methods in the R computing environment and provide access to R code and datasets.

The first edition of Analysis for Longitudinal Data has become a classic. Describing the statistical models and methods for the analysis of longitudinal data, it covers both the underlying statistical theory of each method, and its application to a range of examples from the agricultural and biomedical sciences. The main topics discussed are design issues, exploratory methods of analysis, linear models for continuous data, general linear models fordiscrete data, and models and methods for handling data and missing values. Under each heading, worked examples are presented in parallel with the methodological development, and sufficient detail is given to enable the reader to reproduce the author''s results using the data-sets as an appendix. This secondedition, published for the first time in paperback, provides a thorough and expanded revision of this important text. It includes two new chapters; the first discusses fully parametric models for discrete repeated measures data, and the second explores statistical models for time-dependent predictors.

The first edition of Analysis for Longitudinal Data has become a classic. Describing the statistical models and methods for the analysis of longitudinal data, it covers both the underlying statistical theory of each method, and its application to a range of examples from the agricultural and biomedical sciences. The main topics discussed are design issues, exploratory methods of analysis, linear models for continuous data, general linear models fordiscrete data, and models and methods for handling data and missing values. Under each heading, worked examples are presented in parallel with the methodological development, and sufficient detail is given to enable the reader to reproduce the author''s results using the data-sets as an appendix. This secondedition, published for the first time in paperback, provides a thorough and expanded revision of this important text. It includes two new chapters; the first discusses fully parametric models for discrete repeated measures data, and the second explores statistical models for time-dependent predictors.

The first edition of Analysis for Longitudinal Data has become a classic. Describing the statistical models and methods for the analysis of longitudinal data, it covers both the underlying statistical theory of each method, and its application to a range of examples from the agricultural and biomedical sciences. The main topics discussed are design issues, exploratory methods of analysis, linear models for continuous data, general linear models for discrete data, and models and methods for handling data and missing values. Under each heading, worked examples are presented in parallel with the methodological development, and sufficient detail is given to enable the reader to reproduce the author's results using the data-sets as an appendix. This new edition of Analysis for Longitudinal Data provides a thorough and expanded revision of this important text. It includes two new chapters; the first discusses fully parametric models for discrete repeated measures data, and the second explores statistical models for time-dependent predictors.

Time series analysis is one of several branches of statistics whose practical importance has increased with the availability of powerful computational tools. Methodology that was originally developed for specialized applications, for example in finance or geophysics, is now widely available within general statistical packages. The second edition of Time Series: A Biostatistical Introduction is an introductory account of time series analysis, written from the perspective of applied statisticians whose interests lie primarily in the biomedical and health sciences. This edition has a stronger focus on substantive applications, in which each statistical analysis is directed at a specific research question. Separate chapters cover simple descriptive methods of analysis, including time-plots, smoothing, the correlogram and the periodogram; theory of stationary random processes; discrete-time models for single series; continuous-time models for single series; generalized linear models for time series of counts; models for replicated series; spectral analysis, and bivariate time series.The book is unique in its focus on biomedical and health science applications, which has been strengthened in this second edition. Nevertheless, the methods described are more widely applicable. It should be useful to teachers and students on masters-level degree courses in statistics, biostatistics and epidemiology, and to biomedical and health scientists with a knowledge of statistical methods at undergraduate level. Throughout, examples based on real datasets show a close interplay between statistical method and substantive science. This book will also describe the implementation of the methods in the R computing environment and provide access to R code and datasets.

Time series analysis is one of several branches of statistics whose practical importance has increased with the availability of powerful computational tools. Methodology that was originally developed for specialized applications, for example in finance or geophysics, is now widely available within general statistical packages. The second edition of Time Series: A Biostatistical Introduction is an introductory account of time series analysis, written from the perspective of applied statisticians whose interests lie primarily in the biomedical and health sciences. This edition has a stronger focus on substantive applications, in which each statistical analysis is directed at a specific research question. Separate chapters cover simple descriptive methods of analysis, including time-plots, smoothing, the correlogram and the periodogram; theory of stationary random processes; discrete-time models for single series; continuous-time models for single series; generalized linear models for time series of counts; models for replicated series; spectral analysis, and bivariate time series.The book is unique in its focus on biomedical and health science applications, which has been strengthened in this second edition. Nevertheless, the methods described are more widely applicable. It should be useful to teachers and students on masters-level degree courses in statistics, biostatistics and epidemiology, and to biomedical and health scientists with a knowledge of statistical methods at undergraduate level. Throughout, examples based on real datasets show a close interplay between statistical method and substantive science. This book will also describe the implementation of the methods in the R computing environment and provide access to R code and datasets.

The first edition of Analysis for Longitudinal Data has become a classic. Describing the statistical models and methods for the analysis of longitudinal data, it covers both the underlying statistical theory of each method, and its application to a range of examples from the agricultural and biomedical sciences. The main topics discussed are design issues, exploratory methods of analysis, linear models for continuous data, general linear models for discrete data, and models and methods for handling data and missing values. Under each heading, worked examples are presented in parallel with the methodological development, and sufficient detail is given to enable the reader to reproduce the author's results using the data-sets as an appendix. This second edition, published for the first time in paperback, provides a thorough and expanded revision of this important text. It includes two new chapters; the first discusses fully parametric models for discrete repeated measures data, and the second explores statistical models for time-dependent predictors.

As an introduction to discrete mathematics, this text provides a straightforward overview of the range of mathematical techniques available to students. Assuming very little prior knowledge, and with the minimum of technical complication, it gives an account of the foundations of modern mathematics: logic; sets; relations and functions. It then develops these ideas in the context of three particular topics: combinatorics (the mathematics of counting); probability (the mathematics of chance) and graph theory (the mathematics of connections in networks).Worked examples and graded exercises are used throughout to develop ideas and concepts. The format of this book is such that it can be easily used as the basis for a complete modular course in discrete mathematics.

Geostatistics is concerned with estimation and prediction problems for spatially continuous phenomena, using data obtained at a limited number of spatial locations. The name reflects its origins in mineral exploration, but the methods are now used in a wide range of settings including public health and the physical and environmental sciences. Model-based geostatistics refers to the application of general statistical principles of modeling and inference to geostatistical problems. This volume is the first book-length treatment of model-based geostatistics.The authors have written an expository text, emphasizing statistical methods and applications rather than the underlying mathematical theory. Analyses of datasets from a range of scientific contexts feature prominently, and simulations are used to illustrate theoretical results. Readers can reproduce most of the computational results in the book by using the authors' R-based software package, geoR, whose usage is illustrated in a computation section at the end of each chapter.The book assumes a working knowledge of classical and Bayesian methods of inference, linear models, and generalized linear models, but does not require previous exposure to spatial statistical models or methods. The authors have used the material in MSc-level statistics courses.

Correlated data arise in numerous contexts across a wide spectrum of subject-matter disciplines. Modeling such data present special challenges and opportunities that have received increasing scrutiny by the statistical community in recent years. In October 1996 a group of 210 statisticians and other scientists assembled on the small island of Nantucket, U. S. A. , to present and discuss new developments relating to Modelling Longitudinal and Spatially Correlated Data: Methods, Applications, and Future Direc­ tions. Its purpose was to provide a cross-disciplinary forum to explore the commonalities and meaningful differences in the source and treatment of such data. This volume is a compilation of some of the important invited and volunteered presentations made during that conference. The three days and evenings of oral and displayed presentations were arranged into six broad thematic areas. The session themes, the invited speakers and the topics they addressed were as follows: • Generalized Linear Models: Peter McCullagh-"Residual Likelihood in Linear and Generalized Linear Models" • Longitudinal Data Analysis: Nan Laird-"Using the General Linear Mixed Model to Analyze Unbalanced Repeated Measures and Longi­ tudinal Data" • Spatio---Temporal Processes: David R. Brillinger-"Statistical Analy­ sis of the Tracks of Moving Particles" • Spatial Data Analysis: Noel A. Cressie-"Statistical Models for Lat­ tice Data" • Modelling Messy Data: Raymond J. Carroll-"Some Results on Gen­ eralized Linear Mixed Models with Measurement Error in Covariates" • Future Directions: Peter J.

Assembling a collection of very prominent researchers in the field, the Handbook of Spatial Statistics presents a comprehensive treatment of both classical and state-of-the-art aspects of this maturing area. It takes a unified, integrated approach to the material, providing cross-references among chapters.The handbook begins with a historical intro

Assembling a collection of very prominent researchers in the field, the Handbook of Spatial Statistics presents a comprehensive treatment of both classical and state-of-the-art aspects of this maturing area. It takes a unified, integrated approach to the material, providing cross-references among chapters.The handbook begins with a historical introduction detailing the evolution of the field. It then focuses on the three main branches of spatial statistics: continuous spatial variation (point referenced data); discrete spatial variation, including lattice and areal unit data; and spatial point patterns. The book also contains a section on space–time work as well as a section on important topics that build upon earlier chapters.By collecting the major work in the field in one source, along with including an extensive bibliography, this handbook will assist future research efforts. It deftly balances theory and application, strongly emphasizes modeling, and introduces many real data analysis examples.

Assembling a collection of very prominent researchers in the field, the Handbook of Spatial Statistics presents a comprehensive treatment of both classical and state-of-the-art aspects of this maturing area. It takes a unified, integrated approach to the material, providing cross-references among chapters.The handbook begins with a historical intro

Geostatistics is concerned with estimation and prediction problems for spatially continuous phenomena, using data obtained at a limited number of spatial locations. The name reflects its origins in mineral exploration, but the methods are now used in a wide range of settings including public health and the physical and environmental sciences. Model-based geostatistics refers to the application of general statistical principles of modeling and inference to geostatistical problems. This volume is the first book-length treatment of model-based geostatistics.The authors have written an expository text, emphasizing statistical methods and applications rather than the underlying mathematical theory. Analyses of datasets from a range of scientific contexts feature prominently, and simulations are used to illustrate theoretical results. Readers can reproduce most of the computational results in the book by using the authors' R-based software package, geoR, whose usage is illustrated in a computation section at the end of each chapter.The book assumes a working knowledge of classical and Bayesian methods of inference, linear models, and generalized linear models, but does not require previous exposure to spatial statistical models or methods. The authors have used the material in MSc-level statistics courses.