Interferon Therapy of Multiple Sclerosis

"…an excellent reference for anyone interested in the basic mechanisms of action of the interferons and the clinical chapters provide a clear account of their role in the current management of patients with multiple sclerosis."-The Canadian Journal of Neurological Sciences, 1998

• The Molecular Biology of Interferon-ß from Receptor Binding to Transmembrane Signaling, Lawrence M. Pfeffer and Stefan N. ConstantinescuThe Molecular Biology of Type I Interferons (Interferon- /ß) (Gene Activation, Promoters, Proteins Induced), Thomas DeckerPharmacokinetics of Interferon-ß and the Biological Markers It Induces, Patricia L. WittInterferons and the Central Nervous System Glia, Timothy VartanianEffects of Interferon on the Central Nervous System, Nachum Dafny, Bertha Prieto-Gomez, and Cruz Reyes-VazquezNeuropsychological Effects of Interferon Therapy, Neil H. Pliskin, Anthony T. Reder, and Diane S. GoldsteinThe Effects of Interferon-ß on Cytokines and Immune Responses, Peter RieckmannThe Pathogenetic Role of Interferon- in Multiple Sclerosis, Gianvito Martino and Luigi M. E. GrimaldiThe Effects of Interferons and Other Cytokines on Experimental Autoimmune Encephalomyelitis, Hubertine Heremans and Alfons BilliauEffects of Oral Administration of Type I Interferons on Experimental Autoimmune Encephalomyelitis, Staley A. BrodInterferon- in the Treatment of Multiple Sclerosis, Lorne F. Kastrukoff and Joel J.-F. OgerRecombinant Interferon- in the Treatment of Multiple Sclerosis: Effects on Exacerbation Rate, Magnetic Resonance Imaging of Lesion Activity, and Cytokines, Luca DurelliInteferon ß-1a Treatment of Multiple Sclerosis, Robert M. HerndonInteferon ß-1b (Betaseron) Treatment of Multiple Sclerosis, Robert L. KnoblerEffects of Inteferon ß-1b on Multiple Sclerosis Lesions Evaluated by Magnetic Resonance Imaging and Other Magnetic Resonance Techniques, Robert A. Koopmans, David K. B. Li, Guo Jun Zhao, Elana Brief, Alex MacKay, Irene Vavasour, Ken Whittall, and Donald W. PatyAdverse Effects of Interferons, Richard Cirelli, Kathleen B. Herne, Monica L. McCrary, and Stephen K. TyringInterferon-t: A Potential Treatment for Inflammatory Central Nervous System Disease, Jeanne M. Soos, Joel Schiffenbauer, Howard M. Johnson, and Carol H. PontzerClinical Trials of Multiple Sclerosis, Jeremy C. Hobart and Alan J. ThompsonThe Incidence and Clinical Significance of Antibodies to Interferon-a, Kjell Öberg and Rachel M. McKennaQuantitation and Characterization of Multiple Sclerosis Patient Antibodies to Interferon-ß, Eirik Nestaas, James G. Files, Jeffrey W. Nelson, and Erno Pungor, Jr.