Delivery Systems in Gene Therapy

Gene therapy offers tremendous potential for treating diseases by delivering therapeutic genomic materials to target cells. However, the success of these treatments depends entirely on how effectively these materials can be delivered to the right location. This book addresses this fundamental challenge.The volume examines three main delivery approaches. Viral vectors—including adenovirus, lentivirus, adeno-associated virüs, and others—have proven highly efficient for gene transfer. Non-viral systems offer safer alternatives, ranging from liposomes and nanoparticles to extracellular vesicles. Physical methods such as microinjection, photoporation, and sonoporation provide additional options for introducing genes into cells.International experts contribute chapters covering each delivery system's mechanisms, advantages, and limitations. The book balances technical depth with accessibility, making complex concepts understandable to diverse readers. It highlights recent advances, clinical applications, and future directions in the field.This resource can serve researchers developing new delivery strategies, clinicians implementing gene therapies, graduate students, and professionals in biotechnology and pharmaceutical industries. It can provide essential knowledge for anyone working to advance gene therapy from laboratory to clinical practice.