Dibyajit Lahiri - Böcker

Microbial Biofilms: Challenges and Advances in Metabolomic Study is a volume in the Advances in Biotechnology and Bioengineering Series. The volume covers the metabolomic characteristics of bacterial biofilms and examines the techniques used in the analysis of the metabolomics of the biofilm, its formation, and related infections. The book includes the metabolomics study of various types of biofilms and details new strategies in targeting metabolic pathways for inhibiting the biofilm.

The book also describes various types of metabolomics studies like metabolomics of oral biofilm and metabolomics of biofilm by nosocomial microbes. It also points out the recent advancements on various aspects of metabolomics studies pertaining to biofilms, related infections, their pathogenesis, and present-day treatment strategies.

Microbial Biofilms: Challenges and Advances in Metabolomic Study is a helpful resource to scientists and researchers engaged in biofilm studies, precisely on the metabolomic changes at molecular level occurring in the participating microorganisms. It is also fascinating and thought provoking for the clinicians and health professionals actively involved in the treatment of biofilm mediated chronic infections, since it depicts the pathogenic consequences of the small molecular interactions of the metabolites in biofilm.

Discusses recent trends in biofilms researchDetails newer strategies in treating the biofilm by targeting metabolic pathwaysCovers chronic infections caused by biofilm and their metabolomics studiesExamines various analytical aspects on the metabolomics study of biofilm as well as how metabolomics regulate the formation of the biofilmIncorporates relevant case studies

Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.

Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.

Includes the biology, molecular interaction with target molecule, putative genes and analytical techniques to isolate and identify compounds Incorporates relevant case studies to increase understanding Focuses on recent trends on novel antimicrobial agents and antibiotic resistance research Discusses new arena of diseases, apart from acute and chronic infections

Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech.

Novel extraction, characterization, and application method for phytochemicals in food, pharmacology, and biotechnology Colour illustrations and extensive tables with state-of-art information Covers potential sources of phytochemicals, their extraction and characterization techniques

DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.Offers a comprehensive understanding of genomes in relation to health, forensics, and ancestryProvides detailed technical and operating standards, including for gene editing, genetic testing, ancestral fraction determination, DNA profiling, and ancient DNA analysisGenome and advances in molecular techniques in relation to their value in medical genetics, ancestral fraction determinations, and forensic DNA

A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of a microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance.Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues.Biofilm Associated Antimicrobial Resistance and Its Recovery provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research.Features:A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistanceRecent research in the development of antibiofilm remedies involving biogenic compoundsAdvancements in biofilm detection methodologies with cutting-edge technologiesThis book serves as a resource for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology.

Microbial biofilm plays an important role in the life cycle of microorganisms surviving in diverse and harsh environments such as extremes of temperatures, pH, salinity, nutrient scarcity etc. Biofilm formation is a survival strategy adopted by microorganisms allowing colonization in new niches by dispersal of microbes from the microbial clusters embedded within an outer polymer layer produced by the microorganism itself. This layer comprises of extracellular polymeric substances (EPS) that helps the indwelling microbes to grow and divide in a protected environment against invaders like antimicrobial agents, surfactant, biocides and phagocytic cells of host organisms. Thus, EPS matrix prevents the penetration of antimicrobials thereby allowing the indwelling microbes to survive and give rise to antimicrobial resistance posing threat to human health.The present book highlights a detailed analysis of the mechanism of biofilm formation in both Gram positive and Gram-negative bacteria and the role of quorum sensing signaling mechanism in the genetic regulation pathway. The book titled "Natural Products: Alternative therapeutics as Quorum Sensing (QS) inhibitors" provides a detailed and systematic review of mechanism of quorum sensing in both Gram positive and Gram-negative bacteria and alternative pharmacological developments as a potent solution to the rise of antimicrobial resistance during biofilm formation.Features:A systematic overview of the mechanism of quorum sensing in the development of microbial biofilmsBiofilm formation and its role in the emergence of antimicrobial resistanceRecent pharmacological development of antibiofilm remedies involving biogenic compoundsThis book serves as a reference book for researchers investigating the progression of events during microbial biofilm formation starting from the genetic cascade regulating quorum sensing to secretion of autoinducers and design of safer methodologies for the successful eradication of microbial biofilm. It may also be used as a textbook for a undergraduate level course in microbiology or microbial biotechnology.

The book provides the readers of various discipline an easy understanding of the latest biophysical techniques pertaining to microbiology. Biofilm associated chronic infection is a major health problem and a serious concern to doctors, scientists and other health workers as it develops antibiotic and multi-drug resistance. This book describes various protocols utilized in the detection of the biofilm. The book has been divided into six sub sections which provides pertinent information about the various biophysical techniques and instruments that are used for detecting and analyzing the biofilm formation upon biotic and abiotic surfaces. The readers will be able to identify the techniques that can best cater information to solve the problem at hand. This book attempts to compile the latest information on the recent advances in the various functional aspects of microbial biofilms, their pathogenesis, present day treatments as well as detection strategies.This book is meant forresearchers in the field of microbiology and interested in understanding microbial pathogenesis, quorum sensing and biofilm formation.

The book provides the readers of various discipline an easy understanding of the latest biophysical techniques pertaining to microbiology. Biofilm associated chronic infection is a major health problem and a serious concern to doctors, scientists and other health workers as it develops antibiotic and multi-drug resistance. This book describes various protocols utilized in the detection of the biofilm. The book has been divided into six sub sections which provides pertinent information about the various biophysical techniques and instruments that are used for detecting and analyzing the biofilm formation upon biotic and abiotic surfaces. The readers will be able to identify the techniques that can best cater information to solve the problem at hand. This book attempts to compile the latest information on the recent advances in the various functional aspects of microbial biofilms, their pathogenesis, present day treatments as well as detection strategies.This book is meant forresearchers in the field of microbiology and interested in understanding microbial pathogenesis, quorum sensing and biofilm formation.

Biofilm Applications to Transform the Food Industry is a sweeping introduction to the world of biofilms, illuminating their potential to revolutionize the landscape of both food safety and culinary innovation.

The book unlocks the future of metabolic research with our comprehensive resource, designed for scientists, clinicians, and industry professionals. This expertly curated collection delves into cutting-edge advancements in metabolic pathways, disease mechanisms, and innovative therapeutic strategies. Covering everything from fundamental biochemistry to translational medicine, our content bridges the gap between research and clinical application. Whether you're exploring metabolic disorders, precision medicine, or novel biomarkers, this resource provides in-depth insights backed by the latest scientific discoveries. Elevate your expertise and stay ahead in the dynamic field of metabolic sciences—your essential guide to ground breaking innovations awaits.

Extracellular Polysaccharides: A Novel Frontier in Alternative Food Strategies represents a pioneering venture into the understudied territory of extracellular polysaccharides (EPS) and the potential advancements, such as a reduced reliance on chemical additives, that they can make in the realm of alternative food solutions. This work transcends the conventional discourse on food production challenges by unveiling the multifaceted applications of EPS sourced from diverse organisms like bacteria, fungi, algae, and plants. Experts in the field navigate readers through sustainable extraction techniques, nutritional insights, and cutting-edge technologies, offering a comprehensive roadmap for revolutionizing the global food industry.This book embarks beyond the theoretical, delving into practical applications of EPS in various food products, from enhancing textures to serving as natural preservatives. Addressing current concerns in the food industry, this book serves as a catalyst for change, providing a holistic perspective on EPS that is both scientifically rigorous and accessible to a wide audience. Researchers, industry professionals, and policymakers will find invaluable insights, discovering novel strategies for addressing food security, improving nutritional profiles, and navigating the complex landscape of regulatory considerations. Extracellular Polysaccharides is a guide to a sustainable and resilient food future, empowering its readers to be at the forefront of innovation and positive change.

This book reviews the current concepts in biofilm formation and its implications in human health and disease. In addition, the book elucidates the bacterial biofilm formation on implantable devices and the current approaches to its treatment and prevention.

This book reviews the current concepts in biofilm formation and its implications in human health and disease. In addition, the book elucidates the bacterial biofilm formation on implantable devices and the current approaches to its treatment and prevention.

The book discusses biofilms and adherent communities of microorganisms that play a significant role in livestock-associated infections. It explores the characteristics, formation, and consequences of biofilms in various livestock species and explains their involvement in diseases like mastitis, Johne's disease, caseous lymphadenitis, and more. It also explains intricate aspects of biofilm-related challenges, such as virulence, antibiotic resistance, quorum sensing, and inter-species communication. The book then explores the strategies for combatting biofilm-associated infections, encompassing phytomedicines, novel antimicrobials, and nanomedicines.This book serves as a great resource for researchers, veterinary practitioners and students by addressing these critical issues and providing a comprehensive understanding of biofilm dynamics in livestock infections, fostering improved diagnosis and treatment methodologies.

The volume 1 of the book is an important step to help the readers understand about the principles and practices associated with the extraction, stabilization and therapeutic applications of various bioactive compounds obtained from natural sources.

This book provides in-depth knowledge on the use of various bioactive compounds obtained from natural sources as therapeutics and healthcare solutions.

This book examines the development and applications of system biology approaches for the prevention, diagnosis, and understanding of disease mechanisms. It explores the applications of system biology in infectious diseases, including host-pathogen interaction, and the identification of targets for new therapeutics and intervention strategies. It covers the use of system biology for understanding and treating metabolic disorders towards personalized and precision medicine. The book further discusses the systems biology approaches for understanding the mechanisms of tumor progression and designing more effective cancer therapies. The chapter also reviews the current strategies in autoimmune disease treatment and highlights the opportunity that systems biology represents for the development of better and safer treatments. Importantly, the book discusses the current state of the systems-level understanding of diseases and both the therapeutic and adverse mechanisms of drug actions usingsystem biology approaches. Cutting across the disciplines, this book is a valuable source for researchers in genetics, molecular biology, cell biology, microbiology, and biomedical sciences.​