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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Biologi
    4. Biovetenskap

    DNA in Health, Identity, and Ancestry

    AvHisham Atan Edinur,Edward Kofi Abban

    Häftad, Engelska, 2025

    1 988 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.

    • Offers a comprehensive understanding of genomes in relation to health, forensics, and ancestry
    • Provides detailed technical and operating standards, including for gene editing, genetic testing, ancestral fraction determination, DNA profiling, and ancient DNA analysis
    • Genome and advances in molecular techniques in relation to their value in medical genetics, ancestral fraction determinations, and forensic DNA

    Produktinformation

    • Utgivningsdatum:2025-12-18
    • Mått:191 x 235 x undefined mm
    • Vikt:450 g
    • Format:Häftad
    • Språk:Engelska
    • Antal sidor:522
    • Förlag:Elsevier Science
    • ISBN:9780443339479

    Utforska kategorier

    • Biovetenskap inom Naturvetenskap och teknik
    • Biokemi inom Naturvetenskap och teknik
    • Biologi inom Naturvetenskap och teknik

    Mer om författaren

    Edinur H. Atan is a lecturer of Forensic Science Programme at Universiti Sains Malaysia, Malaysia and Research Fellow of Australian Research Centre for Human Evolution at Griffith University. He did his MSc in Forensic Science at Universiti Sains Malaysia and PhD in Cell and Molecular Biology at Victoria University of Wellington, New Zealand. In 2013, he settled into his current teaching and research role at Universiti Sains Malaysia. He has strong research skills in forensics, molecular biology, genetics and bio-medicine, an impressive list of articles and books published by reputable publishers (e.g. Springer, Lancet, Nature, MDPI, PLOS, Frontiers etc.) and contacts in US, UK, Australia, New Zealand plus Malaysia and elsewhere in Europe, Africa and Middle East.Dr Edward Kofi Abban started his forensic career in 2010 as the Head of the Police DNA laboratory in Ghana. He has over 13 years of experience as a DNA analyst with specialities spanning DNA profiling and DNA investigations form the crime scene to expert representations in courts, DNA-based Identification of missing persons and disaster victims. He is also lecturer in biology education at the at the University of Ghana. He earned his PhD in DNA profiling from the University Sains Malaysia and has contributed significantly to scholarship in areas such as forensic DNA database generation for relevant forensic markers and population genetics of Ghanaian and West African populations. His area of interest include population genetics, wildlife genetics and DNA profiling methodologies. Dibyajit Lahiri, PhD, is Associate Professor in the Department of Biotechnology, University of Engineering and Management, Kolkata, India. His research focuses on biofilm formation on human prostheses and its inhibition through phytochemical and nanocompound interventions, with particular interest in the molecular mechanisms by which natural compounds disrupt biofilm integrity. His work also encompasses computational drug development using bioinformatics approaches. Dr. Lahiri Dr. Lahiri has an extensive publication record, has edited academic volumes in his field, and serves as Associate Editor for multiple international peer-reviewed journals.

    Innehållsförteckning

    • 1. Introduction to human genomes: nuclear and mitochondrial DNA2. Genetic Testing: A Biomedical, Social and Ethical Framework3. CRISPR/Cas9: The Future of Human Gene Editing4. Pharmacogenomics5. Infectious disease diagnosis via DNA analysis6. Donor and recipient matching for transfusion and transplantation surgery7. Circulating free DNA: history, applications, and promises8. Metagenomics of environmental samples9. DNA extraction methods for pathogen analysis10. Characterization and application of environmental DNA in multi-species biofilms11. TLE variants and immune thrombocytopenia susceptibility12. X-chromosome: Genetics, function and health.13. Food intolerance and coeliac disease in past human populations through DNA analysis14. Puzzling ABO Discrepancy Case Resolved Through Molecular Technique15. STR and mitochondrial DNA profiling for casework and paternity cases16. DNA databanking, hit matches and ethical issues17. Forensic parameters in Kedayan inferred using mtDNA data18. The application of dual mitochondrial markers for detecting porcine DNA in gelatine-containing processed food products19. DNA analysis of Elmina plane crash victims: a case study20. Archaeogenetics of human history21. Ancient DNA extraction and amplification techniques22. The usefulness of Y chromosome in the study of past populations23. Human migrations and settlements in Malay Archipelago24. Blood groups, HPA, HNA, cytokines and HLA-G: genetics and ancestry25. Ethnic-specific patterns of GSTM1 and GSTT1 in Malays, Chinese and Indians with specific comparison to Europeans26. The Archaeological Heritage of the Niah National Park’s Caves Complex: History, Current Status, and Future Prospects27. The medical significance of human population genetics in southeast Asia and Oceania28. Genomic ancestry and health from mtDNA perspectives