Sougata Ghosh – författare

Nanotechnology in Medicine and Biology brings together a multidisciplinary team of experts from the fields of materials science, nanotechnology, medicine and biomedical engineering to introduce new nanoscale biomaterials and their applications, diagnosis and treatment of disorders of the human body. The book presents the fundamentals for understanding the design, properties and selection of nanobiomaterials as well as their real-world applications in medicine. Each chapter addresses current regulations, manufacturing processes, and translation issues of nanobiomaterials for key applications. A discussion of current protocols and their benefits and disadvantages is also included.

This book provides comprehensive background and knowledge in the field of nanobiomaterials that is suitable for academics, scientists and clinicians.

Provides fundamental understanding on the design, properties and selection of biomaterials for applications in medicine and biology Reviews current regulations, protocols, manufacturing processes and translation issues of nanobiomaterials for medical applications Discusses tissue repair, wound healing, regenerative medicine, drug delivery, imaging and medical device applications

Nanobiotechnology: Microbes and Plant Assisted Synthesis of Nanoparticles, Mechanisms and Applications covers in detail the green synthesis of nanostructures of tailor-made size, shape and physico-chemical and opto-electronic properties. The rationale behind the selection of bacteria, cyanobacteria, algae, fungi, virus and medicinal plants for the synthesis of biologically active exotic nanoparticles for biomedical applications is also part of this book. It also explores metal recovery, bioconversion, detoxification and removal of heavy metals using nanobiotechnology and discusses the potential of nanobiotechnology to address environmental pollution and toxicity. The book further covers the economic and commercial aspects of such green nanobiotechnology initiatives, its current status in intellectual property rights like patents filed so far globally, technology transfers, and market potential. This information enables one to decipher the scope of biogenic nanoparticles and its prospects. Provides an overview on the general and applied aspects on nanotechnology Gives the scope of exploring bacteria, fungi, algae, virus and medicinal plants for the synthesis of exotic nanoparticles Furnishes a comprehensive report on the underlying molecular mechanisms behind the biosynthesis of nanoparticles Outlines sustainable alternative strategies of bioremediation of heavy metals, metal recovery, detoxification and bioconversion using nanobiotechnology Explores the promises of patenting, technology transfer and commercialization potential of biogenic nanoparticles

Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite.

Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field.

Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform

Agricultural Nanobiotechnology: Biogenic Nanoparticles, Nanofertilizers and Nanoscale Biocontrol Agents presents the most up-to-date advances in nanotechnology to improve the agriculture and food industry with novel nanotools for the controlling of rapid disease diagnostic and enhancement of the capacity of plants to absorb nutrients and resist environmental challenges.

Highlighting the emerging nanofertilizers, nanopesticides and nanoherbicides that are being widely explored in order to overcome the limitations of conventional agricultural supplements, the book provides important insights to enable smart, knowledge-driven selection of nanoscale agricultural biomaterials, coupled with suitable delivery approaches and formulations will lead to promising agricultural innovation using nanotechnology.

Agricultural Nanobiotechnology: Biogenic Nanoparticles, Nanofertilizers and Nanoscale Biocontrol Agents explores emerging innovations in nanobiotechnology for agriculture, food, and natural resources to address the challenges of food security, sustainability, susceptibility, human health, and healthy life. The book is ideal for the multidisciplinary scientists whose goal is to see the use of nanomaterials in agriculture to reduce the amount of spread chemicals, minimize nutrient losses in fertilization and to generate increased yield through pest and nutrient management.

Includes mechanisms of plant-metal interaction and green synthesis Explores the fabrication of nanostructures including carbon nanotubes, quantum dots, encapsulation and emulsions Presents agriculturally focused application insights including nanofertilizers, nanopesticides, and nanoherbicides

Medical Nanobiotechnology: Nanomedicine for Repair, Regeneration, Remodelling, and Recovery thoroughly reviews the potential of functionalized biomaterials as ideal candidates for nanomedicine. This book covers advances in the development of nanotheranostic agents that can simultaneously help in both effective therapy and rapid diagnosis. A range of materials is covered, including their fabrication, characterization, and assessment, as well as their functionalization and incorporation into implants and medical devices. Clinical aspects and challenges are discussed, helping bridge the gap between laboratory research and the translational impact as nanomedicine begins to develop point-of-care customized therapy. This book is an interdisciplinary reference for researchers and R&D groups interested in the development of novel nanobiomaterials for therapeutic applications.

Explores a wide range of regenerative, reparative, and therapeutic applications for novel nanobiomaterials and technologies, including biosensing, drug delivery, wound healing, cell remodeling, tissue engineering, and moreDiscusses the clinical challenges and commercialization of nanomedicine in regenerative medicine, while also offering potential solutionsUtilizes case studies and flow charts to provide clearer understanding of the development techniques and therapeutic applications described

Nanoparticles Synthesis by Soil Microbes: Application in Plant Production and the Environment, a volume in the Plant and Soil Microbiome series, presents an advanced and recent description of plant and soil microbiome in the nanoparticle synthesis and their application in sustainable agriculture and environment. In The book covers the broad aspect of microbial synthesized nanoparticles in their synthesis and application in sustainable agriculture and environmental management in line with the recent and timely further interest in the biogenic synthesis of nanoparticles due to their environmentally-friendly, cost-effective, rapid, and efficient nature.The microbial cell contains various bioactive compounds, and in the last few years, nanoparticle syntheses from the microbial cell have been increasingly sought due to their overall cost effectiveness and less toxic residual products. Microbe-assisted synthesis of nanoparticles could provide a green, environmentally benign, rapid and efficient route for the fabrication of biocompatible nanostructures with diverse physical-chemical and optoelectronic properties.

Covers the plant and soil microbiome and their aspect in the synthesis and application of nanoparticlesAddresses biologically produced nanoparticles and their different propertiesIncludes considerations of regulatory, social, and environmental sustainability impacts

Environmental Nanobiotechnology: Remediation of Refractory Pollutants explores the latest advancements in nanotechnology for environmental remediation. The book delves into the innovative development of biogenic nanoparticles, emphasizing their catalytic capabilities in degrading a wide array of environmental pollutants, including hazardous dyes, pesticides, polyaromatic hydrocarbons, oil spills, and microplastics. The book covers critical topics, including the impact of refractory pollutants and various remediation approaches, the role of bionanomaterials in removing hazardous dyes and pesticides, and the application of nanotechnology in managing oil spills and microplastics. It also addresses the use of biochar, biopolymer-based hydrogels, and engineered nanoparticles for effective water treatment and pollutant removal.Furthermore, it discusses the environmental toxicity and regulatory concerns associated with nanotechnology, ensuring a well-rounded understanding of the field. This is an essential resource for researchers, environmental scientists, and students in fields such as nanotechnology, environmental engineering, and biotechnology. It serves as a guideline for those looking to harness the potential of biogenic nanoparticles in combating environmental pollution, offering a pathway to sustainable solutions and innovative research opportunities.Explains the latest advancements in nanotechnology-driven solutions for sustainable environmental remediationDescribes the biogenic synthesis mechanisms of various nanoparticles, offering detailed insights into their application for the effective removal of recalcitrant pollutantsExplores the fabrication techniques of diverse nanostructures, including metal, metal oxide, and carbon-based nanoparticlesEvaluates the effectiveness of nanobiomaterials in remediating a wide range of pollutants, such as hazardous dyes and microplasticsIntegrates interdisciplinary perspectives from major scientific fields

A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of a microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance.Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues.Biofilm Associated Antimicrobial Resistance and Its Recovery provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research.Features:A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistanceRecent research in the development of antibiofilm remedies involving biogenic compoundsAdvancements in biofilm detection methodologies with cutting-edge technologiesThis book serves as a resource for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology.