Thomas J. Webster – författare

Managerial economics is the application of economic theory and quantitative methods (mathematics and statistics) to the managerial decision-making process. This book will appeal to students with limited prior training in economics and quantitative methods. It assumes that students will have had mathematics training at least through pre-calculus and that they have had a course in elementary statistics. It also expects students to have had an undergraduate course in intermediate microeconomics. The book includes these features: an Online Instructor's Manual; an Online Study Guide; a problem-solving approach to the study of managerial economics that combines the features of a standard managerial economics textbook with those of a separate study guide; a method for helping business students develop the analytical skills necessary for success in the study of managerial economics, finance, and management; and, a more extensive review of mathematical techniques than most comparable textbooks. It contains a separate chapter on game theory, including: noncooperative, simultaneous-move, one- shot games; cooperative, simultaneous-move, infinitely- repeated games (including collusions, cheating rules, and determinants of collusive agreements); cooperative, simultaneous-move, finitely- repeated games; focal-point equilibria; multistage games; bargaining with and without symmetric and asymmetric impatience. It contains a chapter on the time value of money and capital budgeting. There is the accentuation of risk, uncertainty, and the economics of information throughout Book. It is practice oriented, avoiding complex theoretical explanations with cumbersome notation. The problems are included in each section and are made integral to learning and understanding subjects. Math review uses economic relationships instead of general notation. There is excellent balance among motivation, theory, and examples, and clear exposition. It emphasizes utility and applicability, not innovation. Chapters conclude with: chapter review, key terms and concepts, chapter questions, chapter exercises, and selected readings.

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine.

Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine Includes the translational or commercialization status of these new biomaterials Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Nanomedicine: Technologies and Applications, Second Edition provides an important review of this exciting technology and its growing range of applications. In this new edition, all chapters are thoroughly updated and revised, with new content on antibacterial technologies and green nanomedicine. Sections introduce the material, cover their properties, review nanomedicine for therapeutics, imaging and soft tissue engineering, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Other sections cover bone and cartilage tissue engineering, nanostructured particles for antibacterial purposes, advances in green nanomedicine, and using natural nanomedicine to fight disease.

This book is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst also providing a comprehensive introduction for students and academics interested in this field.

Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals, alloys and nanoporous gold and hydroxyapatite coatings Features updated content in all parts, as well as a number of new chapters on antibacterial nanomedicine and green nanomedicine

Nanobiotechnology: Microbes and Plant Assisted Synthesis of Nanoparticles, Mechanisms and Applications covers in detail the green synthesis of nanostructures of tailor-made size, shape and physico-chemical and opto-electronic properties. The rationale behind the selection of bacteria, cyanobacteria, algae, fungi, virus and medicinal plants for the synthesis of biologically active exotic nanoparticles for biomedical applications is also part of this book. It also explores metal recovery, bioconversion, detoxification and removal of heavy metals using nanobiotechnology and discusses the potential of nanobiotechnology to address environmental pollution and toxicity. The book further covers the economic and commercial aspects of such green nanobiotechnology initiatives, its current status in intellectual property rights like patents filed so far globally, technology transfers, and market potential. This information enables one to decipher the scope of biogenic nanoparticles and its prospects. Provides an overview on the general and applied aspects on nanotechnology Gives the scope of exploring bacteria, fungi, algae, virus and medicinal plants for the synthesis of exotic nanoparticles Furnishes a comprehensive report on the underlying molecular mechanisms behind the biosynthesis of nanoparticles Outlines sustainable alternative strategies of bioremediation of heavy metals, metal recovery, detoxification and bioconversion using nanobiotechnology Explores the promises of patenting, technology transfer and commercialization potential of biogenic nanoparticles

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating� antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers.

This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource.

Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials.

Medical Nanobiotechnology: Nanomedicine for Repair, Regeneration, Remodelling, and Recovery thoroughly reviews the potential of functionalized biomaterials as ideal candidates for nanomedicine. This book covers advances in the development of nanotheranostic agents that can simultaneously help in both effective therapy and rapid diagnosis. A range of materials is covered, including their fabrication, characterization, and assessment, as well as their functionalization and incorporation into implants and medical devices. Clinical aspects and challenges are discussed, helping bridge the gap between laboratory research and the translational impact as nanomedicine begins to develop point-of-care customized therapy. This book is an interdisciplinary reference for researchers and R&D groups interested in the development of novel nanobiomaterials for therapeutic applications.

Explores a wide range of regenerative, reparative, and therapeutic applications for novel nanobiomaterials and technologies, including biosensing, drug delivery, wound healing, cell remodeling, tissue engineering, and moreDiscusses the clinical challenges and commercialization of nanomedicine in regenerative medicine, while also offering potential solutionsUtilizes case studies and flow charts to provide clearer understanding of the development techniques and therapeutic applications described

Immunomodulatory Biomaterials and Nano-immunotherapies reviews the general cellular and biochemical barriers of the tumor microenvironment and other immune diseases, the ways they are addressed by modern immunotherapies, and the specific barriers facing particular immunotherapeutic approaches. The latest research on immunomodulatory biomaterials is examined, providing a perspective on their future opportunities in modulating disease treatment strategies. Translational considerations and lessons learned from the various components of nanotechnology-enabled immunotherapies, including conventional immunotherapies,?nucleic acids, nanotechnology, and biotechnology-based therapeutics are assessed. Finally, a framework for the development of the next generation of nanotechnology-enabled immunotherapies is detailed, providing guidance and suggestions for those interested in the development of novel immunomodulatory nanobiomaterials. Immunomodulatory Biomaterials and Nano-immunotherapies is a key reference for researchers and developers working in biomaterials, nanotechnology, immunology, biomedical engineering and pharmaceutical sciences.

Details a range of immunomodulatory biomaterials, including inorganic and organic biomaterials, and looks at their future opportunities in modulating disease treatment strategiesExplores the design, synthesis and use of nanotechnology-enabled immunotherapies, and how their unique characteristics overcome biocompatibility barriersAssesses the clinical and translational considerations of nano-immunotherapies, bridging the gap from bench to bedside

Environmental Nanobiotechnology: Remediation of Refractory Pollutants explores the latest advancements in nanotechnology for environmental remediation. The book delves into the innovative development of biogenic nanoparticles, emphasizing their catalytic capabilities in degrading a wide array of environmental pollutants, including hazardous dyes, pesticides, polyaromatic hydrocarbons, oil spills, and microplastics. The book covers critical topics, including the impact of refractory pollutants and various remediation approaches, the role of bionanomaterials in removing hazardous dyes and pesticides, and the application of nanotechnology in managing oil spills and microplastics. It also addresses the use of biochar, biopolymer-based hydrogels, and engineered nanoparticles for effective water treatment and pollutant removal.Furthermore, it discusses the environmental toxicity and regulatory concerns associated with nanotechnology, ensuring a well-rounded understanding of the field. This is an essential resource for researchers, environmental scientists, and students in fields such as nanotechnology, environmental engineering, and biotechnology. It serves as a guideline for those looking to harness the potential of biogenic nanoparticles in combating environmental pollution, offering a pathway to sustainable solutions and innovative research opportunities.Explains the latest advancements in nanotechnology-driven solutions for sustainable environmental remediationDescribes the biogenic synthesis mechanisms of various nanoparticles, offering detailed insights into their application for the effective removal of recalcitrant pollutantsExplores the fabrication techniques of diverse nanostructures, including metal, metal oxide, and carbon-based nanoparticlesEvaluates the effectiveness of nanobiomaterials in remediating a wide range of pollutants, such as hazardous dyes and microplasticsIntegrates interdisciplinary perspectives from major scientific fields

Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. It presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. Convergence is critical to the success of immunoengineering, and drawing on fields outside of its largely biomaterials-based beginnings, to areas such as biomedical data science, computational medicine, and public health, quickening its progress and broadening its impact. This book surveys biological data from single-cell to spatial omics and proteogenomics, and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. It addresses bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools. The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists, and computational biologists gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.Standardizes AI workflows for immune data, providing templated pipelines, pitfalls, and validation checklistsPresents mechanism-aware modeling that combines predictive ML with causal and dynamical approaches tailored to immune biologyOffers translation and regulatory guidance, including study design, validation, documentation, and deployment considerations

This textbook is an introduction to game theory, which is the systematic analysis of decision-making in interactive settings. Game theory can be of great value to business managers. The ability to correctly anticipate countermove by rival firms in competitive and cooperative settings enables managers to make more effective marketing, advertising, pricing, and other business decisions to optimally achieve the firm’s objectives. Game theory does not always accurately predict how rivals will act in strategic situations, but does identify a decision maker’s best response to situations involving move and countermove. As Nobel Prize winner Thomas Shelling noted: “We may wish to understand how participants actually do conduct themselves in conflict situations; an understanding of the ‘correct’ play may give us a bench mark for the study of actual behavior.” The concise and axiomatic approach to the material presented in this textbook is easily accessible to students with a background in the principles of microeconomics and college mathematics. The selection and organizations of topics makes the textbook appropriate for use in a wide range of curricula by students with different backgrounds.

Game theory is the study of strategic behavior in situations in which the decision makers are aware of the interdependence of their actions. This innovative textbook introduces students to the most basic principles of game theory - move and countermove - with an emphasis on real-world business and economic applications. Students with a background in principles of economics and business mathematics can readily understand most of the material.Demonstration problems in each chapter are designed to enhance the student's understanding of the concepts presented in the text. Many chapters include non-technical applications designed to further the student's intuitive understanding of strategic behavior. Case studies help underscore the usefulness of game theory for analyzing real-world situations. Each chapter concludes with a review and questions and exercises. An online Instructor's Manual with test bank is available to professors who adopt the text.

This book combines the proceedings of Symposium P, The Business of Nanotechnology, and Symposium YY, Compatibility of Nanomaterials , both from the 2009 MRS Fall Meeting in Boston. Papers from Symposium P highlight the constructive disruption caused by the introduction of innovative and value-generating products based on nanotechnology, and underscore the intersections of scientific research and business considerations in the nanotechnology space. The section begins with papers on commercialization challenges in nanotechnology, and specific technologies are also discussed. The final papers in this section include applications of nanosensors for neonatal care, new oxygen sensors and nanocatalysts. Papers from Symposium YY focus on the impact on nanomaterials on health and safety topics that are also critical in the commercialization of nanotechnologies. Presentations bridge the gap between fundamental material science in nanomaterial design, fabrication,and characterization, and cover diversity in the field, from using nanomaterials to fight cancer, infection and regenerate tissues. Several papers also address nanoparticle toxicity. The beginnings of 'green nanotechnology' are also featured.

In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected.The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.

Nanotechnologies are now being applied to health monitoring. Until recently, there has been little research into how to use nanotechnology and sensors in health monitoring. Nanotechnology Enabled In Situ Sensors for Monitoring Health summarizes the research efforts to design sensors based on nanotechnology that can be placed into the body to monitor health. Nanotechnology is being used at an unprecedented pace to both diagnose and treat diseases, rather than conventional approaches that diagnose and treat diseases in a different manner.

Nanotechnologies are now being applied to health monitoring. Until recently, there has been little research into how to use nanotechnology and sensors in health monitoring. Nanotechnology Enabled In Situ Sensors for Monitoring Health summarizes the research efforts to design sensors based on nanotechnology that can be placed into the body to monitor health. Nanotechnology is being used at an unprecedented pace to both diagnose and treat diseases, rather than conventional approaches that diagnose and treat diseases in a different manner.

Each year, thousands of businesses file for bankruptcy protection because managers fail to efficiently organize the company’s operations, misread market trends, pay inadequate attention to product quality, or misinterpret the activities and intentions of rival companies. Perhaps they fail to formulate optimal advertising or financing strategies, procure raw materials and components at least cost, or provide adequate incentives to motivate workers to put forth their best efforts. Managerial economics is the application of economic principles to topics of concern to managers. This textbook develops a framework for predicting managerial responses to changes in the business environment. It combines the various business disciplines with quantitative methods to identify optimal solutions to more efficiently achieve a firm’s organizational objectives. The topics discussed in this textbook are readily accessible to students with a background in the principles of microeconomics and business mathematics. The selection and organizations of topics makes the textbook appropriate for use in a wide range of curricula by students with different backgrounds.

Each year, thousands of businesses file for bankruptcy protection because managers fail to efficiently organize the company’s operations, misread market trends, pay inadequate attention to product quality, or misinterpret the activities and intentions of rival companies. Perhaps they fail to formulate optimal advertising or financing strategies, procure raw materials and components at least cost, or provide adequate incentives to motivate workers to put forth their best efforts. Managerial economics is the application of economic principles to topics of concern to managers. This textbook develops a framework for predicting managerial responses to changes in the business environment. It combines the various business disciplines with quantitative methods to identify optimal solutions to more efficiently achieve a firm’s organizational objectives. The topics discussed in this textbook are readily accessible to students with a background in the principles of microeconomics and business mathematics. The selection and organizations of topics makes the textbook appropriate for use in a wide range of curricula by students with different backgrounds.

This textbook is an introduction to game theory, which is the systematic analysis of decision-making in interactive settings. Game theory can be of great value to business managers. The ability to correctly anticipate countermove by rival firms in competitive and cooperative settings enables managers to make more effective marketing, advertising, pricing, and other business decisions to optimally achieve the firm’s objectives. Game theory does not always accurately predict how rivals will act in strategic situations, but does identify a decision maker’s best response to situations involving move and countermove. As Nobel Prize winner Thomas Shelling noted: “We may wish to understand how participants actually do conduct themselves in conflict situations; an understanding of the ‘correct’ play may give us a bench mark for the study of actual behavior.” The concise and axiomatic approach to the material presented in this textbook is easily accessible to students with a background in the principles of microeconomics and college mathematics. The selection and organizations of topics makes the textbook appropriate for use in a wide range of curricula by students with different backgrounds.

Nanomaterials are able to penetrate nanoscale pores of tissues, possess prolonged circulation, enter cells, and have increased surface area per volume allowing for greater drug loading. For these reasons, nanomaterials are finding numerous uses in medicine including fighting cancer, promoting tissue regeneration, reversing aging, inhibiting infection, limiting inflammation or scar tissue growth, and many others.This book describes the engineering applications and challenges of using nanostructured surfaces and nanomaterials in healthcare. Topics covered include biomimetic coating of calcium phosphates on Ti metals; surface modifications of orthopedic implant materials using an electroplating process; design, fabrication and application of carbon-based nano biomaterials; usage of stem cells in bone and cartilage tissue engineering; nanobiomaterials and 3D bioprinting for osteochondral regeneration; self- assembled peptide hydrogels for biomedical applications; antimicrobial properties of nanomaterials; nanoparticle enhanced radiation therapy for bacterial infection; nanomaterials used in implant technology and their toxicity; challenges of risk assessment of nanomaterials in consumer products and current regulatory status; and the clinical rationale for silicon nitride bioceramics in orthopedics.With contributions from an international selection of researchers this book is essential reading for researchers in industry and academia working at the interfaces of healthcare, engineering and nanotechnology.

Nanotechnology is an emerging and exciting area in the field of implants. Numerous promising developments have been elucidated regarding the use of nanotechnology to regenerate tissues. This important book highlights the potential of nanophase materials to improve hard and soft tissue applications. In all cases, increased tissue regeneration has been observed for bone, cartilage, vascular, bladder, and central/peripheral nervous system tissues.