Clinical Prediction Models (inbunden)
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Format
Inbunden (Hardback)
Språk
Engelska
Serie
Statistics for Biology and Health
Antal sidor
500
Utgivningsdatum
2008-10-20
Upplaga
2009
Förlag
Springer-Verlag New York Inc.
Dimensioner
236 x 155 x 28 mm
Vikt
840 g
ISBN
9780387772431

Clinical Prediction Models

A Practical Approach to Development, Validation, and Updating

av Ewout W Steyerberg, Ewout Steyerberg
Inbunden,  Engelska, 2008-10-20
2630
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Prediction models are important in various fields, including medicine, physics, meteorology, and finance. Prediction models will become more relevant in the medical field with the increase in knowledge on potential predictors of outcome, e.g. from genetics. Also, the number of applications will increase, e.g. with targeted early detection of disease, and individualized approaches to diagnostic testing and treatment. The current era of evidence-based medicine asks for an individualized approach to medical decision-making. Evidence-based medicine has a central place for meta-analysis to summarize results from randomized controlled trials; similarly prediction models may summarize the effects of predictors to provide individu- ized predictions of a diagnostic or prognostic outcome. Why Read This Book? My motivation for working on this book stems primarily from the fact that the development and applications of prediction models are often suboptimal in medical publications. With this book Ihope to contribute to better understanding of relevant issues and give practical advice on better modelling strategies than are nowadays widely used. Issues include: (a) Better predictive modelling is sometimes easily possible; e.g. a large data set with high quality data is available, but all continuous predictors are dich- omized, which is known to have several disadvantages.

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