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Format: Inbunden (Hardback)
Språk: Engelska
Antal sidor: 752
Utgivningsdatum: 2001-07-01
Upplaga: 5
Medarbetare: Travers, Paul / Walport, Mark / Shlomchik, Mark
Illustrationer: 800 ills.
Dimensioner: 275 x 220 x 30 mm
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Antal komponenter: 1
Komponenter: with CD-ROM
ISBN: 9780443070983

Immunobiology

Name: Immunobiology
Price: 6.00 SEK
Availability: OutOfStock
Author: Charles A Janeway
ISBN: 9780443070983

The Immune System in Health and Disease

av Charles A Janeway

Inbunden, Engelska, 2001-07-01

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The central thesis of this book is that the immune system exists to protect the host from infection and that its evolutionary history was shaped by this challenge. Other aspects of immunology are variations on the basic protective function. The first part of the book summarizes the basic immunological concepts and introduces the main 'players'. The middle three parts deal with the main aspects of adaptive immunity. The last part integrates the material at the level of the complete organism in both health and disease.

Part I: An introduction to immunobiology and innate immunity Basic concepts in immunology. Innate immunity. Part II: The recognition of antigen Antigen recognition by B and T cell receptors. The generation of Lymphocyte antigen receptors. Antigen presentation to T lymphocytes. Part III: The development of mature lymphocyte receptor repertoires Signaling through immune system receptors. The development and survival of lymphocytes. Part IV: The adaptive immune response T-cell mediated immunity. The humoral immune response. Adaptive immunity to infection. Part V: The immune system in health and disease Failure of host defense mechanisms. Allergy and hypersensitivityAutoimmunity and transplantation.. Manipulation of the immune response. Part VI: Where the immune system came from and where is immunology going Evolution Appendices The immunologists' toolbox. List of current CDs. Cytokines and their receptors. Chemokines and their receptors.