In this issue of Heart Failure Clinics, guest editors Drs. Alberto Maria Marra and Pablo Demero-Rodriguez bring their considerable expertise to the topic of Pulmonary Vascular Disease: From Bench to Bedside. Top experts discuss follow-up of pulmonary embolism; impact of COVID-19 on pulmonary hypertension; pulmonary embolism and cancer; efficacy of exercise training in pulmonary vascular disease; and much more.