Essentials of Domestic Animal Embryology

"However, this work remains an excellent reference & study handbook for which many embryologists and veterinary students have waited so long since the book by Noden and de Lahunta went out of press. More than the work of McGeady et al., the Essentials of Domestic Animal Embryology by Hyttel et al. is a worthy successor of the latter. It is contemporary in all fields: its approach of the subject, its style and volume, the language, the huge amount of illustrations... and I'm sure it will serve as a reference handbook for many years." Pieter Cornillie Lecturer in Veterinary Embryology at Ghent University May 2010

• CONTENTSINTRODUCTION & GENERAL PRINCIPLES1Cellular and Molecular Mechanisms of Morphogenesis.Cell proliferation: Cell cycle, differentiation, regulation.Cell demise: Apoptosis.Cytoskeleton/Extracellular Matrix/Cell-Matrix interactions.Morphogenesis & Patterning2Comparative Gestation.Distinctions of the Early Embryo, Embryonic and Fetal Periods of Gestation.Species Variations Effecting Gestation Length: Companion, Domestic, Wildlife and Laboratory Animals.Reproductive Cycles: Hormones, Estrous, Organs, Seasonal.Fecundity: Survival Strategies, Conception RatesDIFFERENTIATION OF GERM LAYERS3. Gametogenesis.Mitosis/Meiosis.Oogenesis.Spermatogenesis.Veterinary Clinical Applications/Cases4. Fertilization.Acrosome Reaction.Sperm-Zona Pellucida Interactions.Gamete Fusion.Blocks to Polyspermy.Syngamy and Embryo Activation.Veterinary Clinical Applications/Cases5. Embryo Cleavage and Blastulation.Polarity, Compaction and Cavitation.Embryonic Disc, Primitive Streak and Formation of the Bilaminar Embryo.Veterinary Clinical Applications/Cases 6.Gastrulation, Body Folding and Coelom Formation.Notocord, Neural Tube and Segmentation.Differentiation of Ectoderm, Mesoderm and Endoderm.Body Folding, Coelom Formation and Lung Development.Veterinary Clinical Applications/Cases7.Development of the Peripheral Nervous System.Spinal Cord and Motor/Sensory Innervation.Somite Development8.Comparative Placentation.Extraembryonic Membranes: Amnion, Yolk Sac, Allantois, Chorion.Placental Strategies: Choriovitelline, Chorioallantoic.Species Variations.Veterinary Clinical Applications/CasesSYSTEMS DEVELOPMENT9.Development of the Limbs.Limb Bud Formation.Apical Ectodermal Ridge.Development of the Appendicular Skeleton, Musculature, Vasculature and Innervation.Differentiation of Distal Appendages: Digit Formation.Veterinary Clinical Applications/Cases10.Development of the Heart.Primitive Heart Tube Formation.Development of Heart Chambers and Valves.Development of the Conduction System.Veterinary Clinical Applications/Cases11.Development of the Vascular System.Formation of the Aortic Arches and the Arterial System.Development of the Vitelline, Umbilical and Cardinal Venous System.The Coronary Vasculature.Circulatory changes at Parturition.Veterinary Clinical Applications/Cases 12.Development of the Gastrointestinal System.The Enteric Canal.Stomach, Pancreas, Liver and Spleen.Development of Peritoneum and Formation of Mesenteries.Rotation and Fixation of the Midgut.Differentiation of the Large Bowel.Septation and Differentiation of the Cloaca.Veterinary Clinical Applications/Cases 13.Development of the Urogenital System.Pronephros Differentiation.Development of the Mesonephric and Metanephric Kidneys.Urogenital Ridge and Gonad Development.Development of the Urogentital Duct Systems and External Genitalia.Veterinary Clinical Applications/Cases14.Development of the Head and Neck.Development of the Skull and Vertebrae.Differentiation of Pharyngeal Arch Structures and Pouch Derivatives.Development of the Palate, Tongue and Pituitary.Development of Facial Structures.Veterinary Clinical Applications/Cases15.Development of the Brain and Cranial Nerves.Regional Differentiation and Functional Relationships.Development of the Ventricular System.Development and Function of the Cranial Nerves.Veterinary Clinical Applications/Cases16.Development of the Eyes and Ears.Formation of the Ear.Formation of the Eye.Veterinary Clinical Applications/Cases17.Development of the Integumentary System.Differentiation of the Epidermis and Dermis.Development of Epidermal Glands including Mammary Glands.Formation of Hair and Teeth.Veterinary Clinical Applications/CasesCLINICAL AND APPLIED SYSTEMS18.Teratology.Genetic & Congenital.Critical Periods & Teratogenic Agents.Maternal/Fetal Interactions.Specie-Specific Manifestations19.Assisted Reproductive Technologies.Artificial Insemination and Embryo/Gamete Transfer (ET,GIFT, ZIFT, etc).Cryopreservation of Germplasm.In Vitro Maturation, Fertilization and Embryo Production.Embryo Micromanipulation: Splitting, ICSI, Transgenics, Embryonic Stem Cells/ Chimeras, Cloning20.Applied Embryology: Veterinary and Societal Issues.The Role of the Veterinarian.Contemporary IssuesAdditional Reading - ReferencesGlossaryIndex