Molecular and Cellular Mechanisms of Antibody Activity

Inbunden, Engelska, 2013

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Beskrivning

Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. This book examines how these new results have dramatically changed our view of how antibodies function in vivo.

Produktinformation

Utgivningsdatum:2013-05-22
Mått:155 x 235 x 22 mm
Vikt:592 g
Format:Inbunden
Språk:Engelska
Antal sidor:294
Upplaga:2013
Förlag:Springer-Verlag New York Inc.
ISBN:9781461471066

Utforska kategorier

Patologi inom Medicin
Onkologi inom Medicin

Innehållsförteckning

IgM and IgD in infection and inflammatory diseases.- Immunoglobulin A – molecular mechanisms of function and role in immune defense.- Crystal structures of human IgG Fc-fragments and their complexes with Fc Receptors.- The role of IgG in immune responses.- Molecular and cellular pathways involved in the anti-inflammatory activity of IgG.- Example of the Pathogenic Potential of Two Sets of Autoantibodies: Anti-RBC and IgG3 RF Cryoglobulins.- Cross-talk between antibodies, IgG Fc receptors and the complement system.- Regulation of immunological responses by the neonatal Fc receptor for IgG, FcRn.- Antibody mediated regulation of humoral immunity.- Engineered antibody derivatives in preclinical and clinical development.