David Harris is Associate Dean of the Western Clinical School of the University of Sydney, at Westmead Hospital. He is a nephrologist and prior to his appointment as Associate Dean he was Director of Nephrology and Dialysis in Western Sydney. He is also a Past-President of the Australian and New Zealand Society of Nephrology, Chairman of the Medical and Scientific Advisory Committee and Director of Kidney Health Australia, Chairman of the Advisory Committee of the Australasian Kidney Trials Network, a member of the Executive of the Asian Pacific Society and International Societies of Nephrology, and Editor-in-Chief of the journal Nephrology.

• Pocket Guide to Clinical Dialysis 2e About the editors v About the contributors vi Preface ix List of protocols x List of tables xiv List of figures xvii Abbreviations xviii Part 1 Introduction 1 Chapter 1.1 Normal kidney function 3 Chapter 1.2 Stages of chronic kidney disease 5 Chapter 1.3 Assessment of the patient with chronic kidney disease 8 Chapter 1.4 Limitations of dialysis as replacement fornormal kidney function 18 Chapter 1.5 Early chronic kidney disease and preparation of the patient for maintenance dialysis 20 Chapter 1.6 Conservative therapy for advanced chronickidney disease 29 Part 2 General care of patients with chronickidney disease 37 Chapter 2.1 Chronic kidney disease mineral and bonedisorder 39 Chapter 2.2 Cardiovascular risk and its management 52 Chapter 2.3 Erythropoiesis 61 Chapter 2.4 Bleeding and thrombosis 68 Chapter 2.5 Endocrine disturbances of chronickidney disease 76 Chapter 2.6 Infection control 84 Chapter 2.7 Pregnancy and dialysis 90 Chapter 2.8 Preparation for kidney transplantation 97 Chapter 2.9 Drug prescribing to patients on dialysis 103 Chapter 2.10 Nutrition 108 Chapter 2.11 Routine monitoring of dialysis patients 115 Chapter 2.12 Testing health-related quality of lifeand functional ability 119 Part 3 Haemodialysis 123 Chapter 3.1 Haemodialysis physiology 125 Chapter 3.2 Haemodialysis equipment 132 Chapter 3.3 Haemodialysis adequacy and prescription 137 Chapter 3.4 Vascular access for haemodialysis 148 Chapter 3.5 Anticoagulation for haemodialysis 169 Chapter 3.6 Managing the first haemodialysis treatmentin a patient with end-stage kidney disease 173 Chapter 3.7 Complications during haemodialysis 176 Chapter 3.8 Haemodialysis in children 186 Part 4 Chronic peritoneal dialysis 189 Chapter 4.1 General principles 191 Chapter 4.2 Peritoneal membrane physiology 196 Chapter 4.3 Peritoneal dialysis access and complications 202 Chapter 4.4 Peritoneal dialysis solutions and connection systems 216 Chapter 4.5 Prescribing and assessing the adequacyof peritoneal dialysis 225 Chapter 4.6 Preserving residual renal and peritonealmembrane function 234 Chapter 4.7 Abnormal fluid volume status inchronic peritoneal dialysis 240 Chapter 4.8 Peritonitis and exit-site infections 245 Chapter 4.9 Non-infective complications of chronicperitoneal dialysis 256 Part 5 Acute dialysis 263 Chapter 5.1 Dialysis for acute kidney injury 265 Chapter 5.2 Extracorporeal therapy for acute poisoning 277 Chapter 5.3 Plasmapheresis 283 Index 289

David Harris is Associate Dean of the Western Clinical School of the University of Sydney, at Westmead Hospital. He is a nephrologist and prior to his appointment as Associate Dean he was Director of Nephrology and Dialysis in Western Sydney. He is also a Past-President of the Australian and New Zealand Society of Nephrology, Chairman of the Medical and Scientific Advisory Committee and Director of Kidney Health Australia, Chairman of the Advisory Committee of the Australasian Kidney Trials Network, a member of the Executive of the Asian Pacific Society and International Societies of Nephrology, and Editor-in-Chief of the journal Nephrology.

• Pocket Guide to Clinical Dialysis 2e About the editors v About the contributors vi Preface ix List of protocols x List of tables xiv List of figures xvii Abbreviations xviii Part 1 Introduction 1 Chapter 1.1 Normal kidney function 3 Chapter 1.2 Stages of chronic kidney disease 5 Chapter 1.3 Assessment of the patient with chronic kidney disease 8 Chapter 1.4 Limitations of dialysis as replacement fornormal kidney function 18 Chapter 1.5 Early chronic kidney disease and preparation of the patient for maintenance dialysis 20 Chapter 1.6 Conservative therapy for advanced chronickidney disease 29 Part 2 General care of patients with chronickidney disease 37 Chapter 2.1 Chronic kidney disease mineral and bonedisorder 39 Chapter 2.2 Cardiovascular risk and its management 52 Chapter 2.3 Erythropoiesis 61 Chapter 2.4 Bleeding and thrombosis 68 Chapter 2.5 Endocrine disturbances of chronickidney disease 76 Chapter 2.6 Infection control 84 Chapter 2.7 Pregnancy and dialysis 90 Chapter 2.8 Preparation for kidney transplantation 97 Chapter 2.9 Drug prescribing to patients on dialysis 103 Chapter 2.10 Nutrition 108 Chapter 2.11 Routine monitoring of dialysis patients 115 Chapter 2.12 Testing health-related quality of lifeand functional ability 119 Part 3 Haemodialysis 123 Chapter 3.1 Haemodialysis physiology 125 Chapter 3.2 Haemodialysis equipment 132 Chapter 3.3 Haemodialysis adequacy and prescription 137 Chapter 3.4 Vascular access for haemodialysis 148 Chapter 3.5 Anticoagulation for haemodialysis 169 Chapter 3.6 Managing the first haemodialysis treatmentin a patient with end-stage kidney disease 173 Chapter 3.7 Complications during haemodialysis 176 Chapter 3.8 Haemodialysis in children 186 Part 4 Chronic peritoneal dialysis 189 Chapter 4.1 General principles 191 Chapter 4.2 Peritoneal membrane physiology 196 Chapter 4.3 Peritoneal dialysis access and complications 202 Chapter 4.4 Peritoneal dialysis solutions and connection systems 216 Chapter 4.5 Prescribing and assessing the adequacyof peritoneal dialysis 225 Chapter 4.6 Preserving residual renal and peritonealmembrane function 234 Chapter 4.7 Abnormal fluid volume status inchronic peritoneal dialysis 240 Chapter 4.8 Peritonitis and exit-site infections 245 Chapter 4.9 Non-infective complications of chronicperitoneal dialysis 256 Part 5 Acute dialysis 263 Chapter 5.1 Dialysis for acute kidney injury 265 Chapter 5.2 Extracorporeal therapy for acute poisoning 277 Chapter 5.3 Plasmapheresis 283 Index 289

David Harris is Associate Dean of the Western Clinical School of the University of Sydney, at Westmead Hospital. He is a nephrologist and prior to his appointment as Associate Dean he was Director of Nephrology and Dialysis in Western Sydney. He is also a Past-President of the Australian and New Zealand Society of Nephrology, Chairman of the Medical and Scientific Advisory Committee and Director of Kidney Health Australia, Chairman of the Advisory Committee of the Australasian Kidney Trials Network, a member of the Executive of the Asian Pacific Society and International Societies of Nephrology, and Editor-in-Chief of the journal Nephrology.

• Pocket Guide to Clinical Dialysis 2e About the editors v About the contributors vi Preface ix List of protocols x List of tables xiv List of figures xvii Abbreviations xviii Part 1 Introduction 1 Chapter 1.1 Normal kidney function 3 Chapter 1.2 Stages of chronic kidney disease 5 Chapter 1.3 Assessment of the patient with chronic kidney disease 8 Chapter 1.4 Limitations of dialysis as replacement fornormal kidney function 18 Chapter 1.5 Early chronic kidney disease and preparation of the patient for maintenance dialysis 20 Chapter 1.6 Conservative therapy for advanced chronickidney disease 29 Part 2 General care of patients with chronickidney disease 37 Chapter 2.1 Chronic kidney disease mineral and bonedisorder 39 Chapter 2.2 Cardiovascular risk and its management 52 Chapter 2.3 Erythropoiesis 61 Chapter 2.4 Bleeding and thrombosis 68 Chapter 2.5 Endocrine disturbances of chronickidney disease 76 Chapter 2.6 Infection control 84 Chapter 2.7 Pregnancy and dialysis 90 Chapter 2.8 Preparation for kidney transplantation 97 Chapter 2.9 Drug prescribing to patients on dialysis 103 Chapter 2.10 Nutrition 108 Chapter 2.11 Routine monitoring of dialysis patients 115 Chapter 2.12 Testing health-related quality of lifeand functional ability 119 Part 3 Haemodialysis 123 Chapter 3.1 Haemodialysis physiology 125 Chapter 3.2 Haemodialysis equipment 132 Chapter 3.3 Haemodialysis adequacy and prescription 137 Chapter 3.4 Vascular access for haemodialysis 148 Chapter 3.5 Anticoagulation for haemodialysis 169 Chapter 3.6 Managing the first haemodialysis treatmentin a patient with end-stage kidney disease 173 Chapter 3.7 Complications during haemodialysis 176 Chapter 3.8 Haemodialysis in children 186 Part 4 Chronic peritoneal dialysis 189 Chapter 4.1 General principles 191 Chapter 4.2 Peritoneal membrane physiology 196 Chapter 4.3 Peritoneal dialysis access and complications 202 Chapter 4.4 Peritoneal dialysis solutions and connection systems 216 Chapter 4.5 Prescribing and assessing the adequacyof peritoneal dialysis 225 Chapter 4.6 Preserving residual renal and peritonealmembrane function 234 Chapter 4.7 Abnormal fluid volume status inchronic peritoneal dialysis 240 Chapter 4.8 Peritonitis and exit-site infections 245 Chapter 4.9 Non-infective complications of chronicperitoneal dialysis 256 Part 5 Acute dialysis 263 Chapter 5.1 Dialysis for acute kidney injury 265 Chapter 5.2 Extracorporeal therapy for acute poisoning 277 Chapter 5.3 Plasmapheresis 283 Index 289