Handbook of Homogeneous Hydrogenation, 3 Volume Set

Kees Elsevier was born in 1957 in Den Haag, The Netherlands. He obtained his masters and PhD in chemistry at Utrecht University (1984) with Dr P. Vermeer and Professor H.J.T. Bos, on the topic of "transition-metal mediated synthesis of chiral allenes". Subsequently he moved to the University of Amsterdam, where he has developed his interests in organometallic chemistry and catalysis employing late-transition-metal compounds. He became associate professor in 1991, and then occupied the John van Geuns chair for developing transition-metal-NMR spectroscopy from 1995 till 1999. Since 1999 he holds the chair of Molecular Inorganic Chemistry at the University of Amsterdam. He has been visiting professor twice at the Weizmann Institute of Science, Israel, and at the Universities of Strasbourg and Toulouse (France). He is co-author of about 180 scientific papers on various topics in organometallic chemistry, homogeneous catalysis, and (transition metal) NMR spectroscopy, including contributions to several books. He has lately focused on Pd-catalyzed hydrogenations, involving N-ligands and N-heterocyclic carbenes, as well as catalysis involving aggregates (micelles and vesicles) of metallo-amphiphiles. He has supervised 20 PhD graduations. Kees serves on the advisory board of several scientific journals and he is scientific director of the Holland Research School of Molecular Chemistry. Hans de Vries was born in Amsterdam, the Netherlands (1951). In 1979 he received his Ph.D from the University of Groningen, were he worked under the guidance of Richard M. Kellogg on chiral, bridged dihydropyridines as NADH-mimetics. After a postdoctoral stint at Brandeis University, Waltham, USA with Jim Hendrickson (total synthesis of Methoxatin or PQQ) from 79-81 he moved back to Europe. From 1982-1988 he worked as medicinal chemist for Sandoz, first in Vienna, afterwards in London. Being more interested in chemistry than drugs he moved back to the Netherlands, were he took up employment with DSM, a multinational specialty chemicals company. His current job is Principal Scientist Homogeneous Catalysis for Fine Chemicals. Since 1998 he has been appointed as part-time professor at the University of Groningen. In 2000 he was appointed visiting industrial professor at the Univeristy of Bristol. During 2005 he was a visiting professor at the Universite Louis Pasteur, Strasbourg. His research interests are in the area of asymmetric hydrogenation (MonoPhos), aromatic substitution ("homeopathic" palladium), hydroformylation, metathesis, combinations of enzymes with transition metal catalysis, HTS, combinatorial catalysis and process intensification. He is (co-)author of 20 patents and over 100 publications. He is married and has three children.

"The information is laid out well ... clear diagrams ...clear and comprehensive overview..."Platinum Metals Review

• Volume 1Part I Introduction, Organometallic Aspects and Mechanism of Homogeneous Hydrogenation1 Rhodium 3Luis A. Oro and Daniel Carmona2 Iridium 31Robert H. Crabtree3 Ruthenium and Osmium 45Robert H. Morris4 Palladium and Platinum 71Paolo Pelagatti5 Nickel 93Elisabeth Bouwman6 Hydrogenation with Early Transition Metal, Lanthanide and Actinide Complexes 111Christophe Copéret7 Ionic Hydrogenations 153R. Morris Bullock8 Homogeneous Hydrogenation by Defined Metal Clusters 199Roberto A. Sánchez-Delgado9 Homogeneous Hydrogenation: Colloids – Hydrogenation with Noble Metal Nanoparticles 217Alain Roucoux and Karine Philippot10 Kinetics of Homogeneous Hydrogenations: Measurement and Interpretation 257Hans-Joachim Drexler, Angelika Preetz, Thomas Schmidt, and Detlef HellerPart II Spectroscopic Methods in Homogeneous Hydrogenation11 Nuclear Magnetic Resonance Spectroscopy in Homogeneous Hydrogenation Research 297N. Koen de Vries12 Parahydrogen-Induced Polarization: Applications to Detect Intermediates of Catalytic Hydrogenations 313Joachim Bargon13 A Tour Guide to Mass Spectrometric Studies of Hydrogenation Mechanisms 359Corbin K. Ralph, Robin J. Hamilton, and Steven H. BergensPart III Homogeneous Hydrogenation by Functional Groups14 Homogeneous Hydrogenation of Alkynes and Dienes 375Alexander M. Kluwer and Cornelis J. Elsevier15 Homogeneous Hydrogenation of Aldehydes, Ketones, Imines and Carboxylic Acid Derivatives: Chemoselectivity and Catalytic Activity 413Matthew L. Clarke and Geoffrey J. Roff16 Hydrogenation of Arenes and Heteroaromatics 455Claudio Bianchini, Andrea Meli, and Francesco Vizza17 Homogeneous Hydrogenation of Carbon Dioxide 489Philip G. JessopVolume 218 Dehalogenation Reactions 513Attila Sisak and Ottó Balázs Simon19 Homogeneous Catalytic Hydrogenation of Polymers 547Garry L. Rempel, Qinmin Pan, and Jialong Wu20 Transfer Hydrogenation Including the Meerwein-Ponndorf-Verley Reduction 585Dirk Klomp, Ulf Hanefeld, and Joop A. Peters21 Diastereoselective Hydrogenation 631Takamichi Yamagishi22 Hydrogen-Mediated Carbon–Carbon Bond Formation Catalyzed by Rhodium 713Chang-Woo Cho and Michael J. KrischePart IV Asymmetric Homogeneous Hydrogenation23 Enantioselective Alkene Hydrogenation: Introduction and Historic Overview 745David J. Ager24 Enantioselective Hydrogenation: Phospholane Ligands 773Christopher J. Cobley and Paul H. Moran25 Enantioselective Hydrogenation of Alkenes with Ferrocene-Based Ligands 833Hans-Ulrich Blaser, Matthias Lotz, and Felix Spindler26 The other Bisphosphine Ligands for Enantioselective Alkene Hydrogenation 853Yongxiang Chi, Wenjun Tang, and Xumu Zhang27 Bidentate Ligands Containing a Heteroatom–Phosphorus Bond 883Stanton H.L. Kok, Terry T.-L. Au-Yeung, Hong Yee Cheung, Wing Sze Lam, Shu Sun Chan, and Albert S. C. Chan28 Enantioselective Alkene Hydrogenation: Monodentate Ligands 995Michel van den Berg, Ben L. Feringa, and Adriaan J. Minnaard29 P,N and Non-Phosphorus Ligands 1029Andreas Pfaltz and Sharon BellVolume 330 Enantioselective Hydrogenation of Unfunctionalized Alkenes 1049Andreas Pfaltz and Sharon Bell31 Mechanism of Enantioselective Hydrogenation 1073John M. Brown32 Enantioselective Ketone and -Keto Ester Hydrogenations (Including Mechanisms) 1105Takeshi Ohkuma and Ryoji Noyori33 Rhodium-Catalyzed Enantioselective Hydrogenation of Functionalized Ketones 1165André Mortreux and Abdallah Karim34 Enantioselective Hydrogenation of C=N Functions and Enamines 1193Felix Spindler and Hans-Ulrich Blaser35 Enantioselective Transfer Hydrogenation 1215A. John Blacker36 High-Throughput Experimentation and Ligand Libraries 1245Johannes G. de Vries and Laurent Lefort37 Industrial Applications 1279Hans-Ulrich Blaser, Felix Spindler, and Marc ThommenPart V Phase Separation in Homogeneous Hydrogenation38 Two-Phase Aqueous Hydrogenations 1327Ferenc Joó and Ágnes Kathó39 Supercritical and Compressed Carbon Dioxide as Reaction Medium and Mass Separating Agent for Hydrogenation Reactions using Organometallic Catalysts 1361Walter Leitner40 Fluorous Catalysts and Fluorous Phase Catalyst Separation for Hydrogenation Catalysis 1377Elwin de Wolf and Berth-Jan Deelman41 Catalytic Hydrogenation using Ionic Liquids as Catalyst Phase 1389Peter Wasserscheid and Peter Schulz42 Immobilization Techniques 1421Imre Tóth and Paul C. van GeemPart VI Miscellaneous Topics in Homogeneous Hydrogenation43 Transition Metal-Catalyzed Regeneration of Nicotinamide Cofactors 1471Stephan Lütz44 Catalyst Inhibition and Deactivation in Homogeneous Hydrogenation 1483Detlef Heller, André H.M. de Vries, and Johannes G. de Vries45 Chemical Reaction Engineering Aspects of Homogeneous Hydrogenations 1517Claude de Bellefon and Nathalie PestreSubject Index 1547