Nuclear Magnetic Resonance Spectroscopy in Molecular Biology

The 11th Jeruaalem SympOlium continued the tradition of the pIe __ t and excitiDs meetiDp wbich 0DCe a year &ather dlJtingni,bed ICientiltl, the wodd's most renowned experts in a specific field of quantum chemistry and biochemistry. in the impressive IUrroundinp of the Israel Academy of Sciences and Humanities. We wiah to thank aU those who made this meetiDg pOllible and contributed to its IUcceSS: the Baron Edmond de Rothschild whOle continuous generosity suarantees the perenniality of our venture, the Israel Academy of Sciences and Humanities and in particu1ar its President Professor A. DvoIItIky, the Hebrew UDivenity of Jerusalem, and Professor David GiDsburg, for their devoted co11aboration. Mn. Abipil Hyam must be thanked for her decisive contribution to the efficiency and IUCcess of the local IIIIII1geDleJlts. Bernard Pulhnan v TABLE OF CONTENTS ~~e v D. G. Gorenstein / P-31 NMR of nucleic acids. Bond angle and torsional effects 1 H. lwahashi and Y. Kyogoku / NMR studies on dynamic properties of nucleic acid base pairs in nonaqueous solvents 17 M. M. Dhingra and R. H. Sarma / NMR studies and minimum energy confonnation calculations on the S'-tenninus of mammalian mRNA 31 H.-D. Ludemann and E. Westho/ / Solution confonnations of purine (JJ) nucleosides and analogs 41 P. Biichner, F. Blomberg, and H. Ruterjans / Nitrogen-IS nuclear magnetic resonance spectroscopy of lSN-Iabeled nucleotides. Investigations of Ribonuclease A -Nucleotide interactions S3 D. B.