"This is an extensive, detailed review of current knowledge in this highly complicated area...an excellent reference that would be a welcome addition to most libraries. Score: 97 - 5 Stars" --Doodys.com, January 2015

• Section I: Neurocircuitry of Alcohol Dependence 1. Frameworks of alcohol addiction: Alcohol addiction as a reward deficit and stress surfeit disorder2. Basal ganglia networks and mechanisms of voluntary actions:  implications for alcohol addiction and dependence3. Prefrontal limbic striatal circuits and alcohol addiction in humans4. Molecular adaptations in mesolimbic circuitry and pathological ethanol intake5. The bed nucleus of the stria terminalis: A critical site of ethanol-induced alterations in neurotransmission6. Stress and alcohol drinking behavior7. Alcohol and developing neuronal circuits8. Human imaging studies of brain circuitry disrupted by alcoholismSection II: Neurosignaling and Neuroplasticity of Alcohol Dependence 9. From signaling pathways to behavior: The light and dark sides of alcohol10. Glutamate signaling in alcohol abuse and dependence11. Central amygdala neuroplasticity in alcohol dependence 12. Neural plasticity in the ventral tegmental area and alcohol dependence13. Extrasynaptic GABA receptors and alcohol  14. Cannabinoids and the neural actions of alcohol15. Impact of alcohol abuse and dependence on the structure and function of the prefrontal cortex16. Molecular mechanisms underlying the development of functional and behavioral tolerance to alcoholSection III: Gene and Behavior17. Alcohol and the brain: An epigenetic viewpoint18. The genetic complexity of alcohol drinking in rodents19. Alcohol dependence, withdrawal, and relapse20. Insights from non human primates on risks for drinking to dependence21. The potential role of glucocorticoids and the HPA axis in alcohol dependence22. Anxiety and alcohol use disorders: A perspective from molecular and epigenetic studies23. The genetics of alcohol responses of invertebrate model systems24. MicroRNAs in alcohol abuse and toxicity25. Gene and behavior26. Complex genetics of alcoholism

"This is an extensive, detailed review of current knowledge in this highly complicated area...an excellent reference that would be a welcome addition to most libraries. Score: 97 - 5 Stars" --Doodys.com, January 2015

• Section I: Neurocircuitry of Alcohol Dependence 1. Frameworks of alcohol addiction: Alcohol addiction as a reward deficit and stress surfeit disorder2. Basal ganglia networks and mechanisms of voluntary actions:  implications for alcohol addiction and dependence3. Prefrontal limbic striatal circuits and alcohol addiction in humans4. Molecular adaptations in mesolimbic circuitry and pathological ethanol intake5. The bed nucleus of the stria terminalis: A critical site of ethanol-induced alterations in neurotransmission6. Stress and alcohol drinking behavior7. Alcohol and developing neuronal circuits8. Human imaging studies of brain circuitry disrupted by alcoholismSection II: Neurosignaling and Neuroplasticity of Alcohol Dependence 9. From signaling pathways to behavior: The light and dark sides of alcohol10. Glutamate signaling in alcohol abuse and dependence11. Central amygdala neuroplasticity in alcohol dependence 12. Neural plasticity in the ventral tegmental area and alcohol dependence13. Extrasynaptic GABA receptors and alcohol  14. Cannabinoids and the neural actions of alcohol15. Impact of alcohol abuse and dependence on the structure and function of the prefrontal cortex16. Molecular mechanisms underlying the development of functional and behavioral tolerance to alcoholSection III: Gene and Behavior17. Alcohol and the brain: An epigenetic viewpoint18. The genetic complexity of alcohol drinking in rodents19. Alcohol dependence, withdrawal, and relapse20. Insights from non human primates on risks for drinking to dependence21. The potential role of glucocorticoids and the HPA axis in alcohol dependence22. Anxiety and alcohol use disorders: A perspective from molecular and epigenetic studies23. The genetics of alcohol responses of invertebrate model systems24. MicroRNAs in alcohol abuse and toxicity25. Gene and behavior26. Complex genetics of alcoholism

"This is an extensive, detailed review of current knowledge in this highly complicated area...an excellent reference that would be a welcome addition to most libraries. Score: 97 - 5 Stars" --Doodys.com, January 2015

• Section I: Neurocircuitry of Alcohol Dependence 1. Frameworks of alcohol addiction: Alcohol addiction as a reward deficit and stress surfeit disorder2. Basal ganglia networks and mechanisms of voluntary actions:  implications for alcohol addiction and dependence3. Prefrontal limbic striatal circuits and alcohol addiction in humans4. Molecular adaptations in mesolimbic circuitry and pathological ethanol intake5. The bed nucleus of the stria terminalis: A critical site of ethanol-induced alterations in neurotransmission6. Stress and alcohol drinking behavior7. Alcohol and developing neuronal circuits8. Human imaging studies of brain circuitry disrupted by alcoholismSection II: Neurosignaling and Neuroplasticity of Alcohol Dependence 9. From signaling pathways to behavior: The light and dark sides of alcohol10. Glutamate signaling in alcohol abuse and dependence11. Central amygdala neuroplasticity in alcohol dependence 12. Neural plasticity in the ventral tegmental area and alcohol dependence13. Extrasynaptic GABA receptors and alcohol  14. Cannabinoids and the neural actions of alcohol15. Impact of alcohol abuse and dependence on the structure and function of the prefrontal cortex16. Molecular mechanisms underlying the development of functional and behavioral tolerance to alcoholSection III: Gene and Behavior17. Alcohol and the brain: An epigenetic viewpoint18. The genetic complexity of alcohol drinking in rodents19. Alcohol dependence, withdrawal, and relapse20. Insights from non human primates on risks for drinking to dependence21. The potential role of glucocorticoids and the HPA axis in alcohol dependence22. Anxiety and alcohol use disorders: A perspective from molecular and epigenetic studies23. The genetics of alcohol responses of invertebrate model systems24. MicroRNAs in alcohol abuse and toxicity25. Gene and behavior26. Complex genetics of alcoholism