"The Contributors are a 'who's who' of the diuretic field, and the book encompasses a broad range of topics from very basic molecular concepts to practical and clinical uses of diuretics. The book is a classic in its field. It will be widely cited as a reference and should be used by physicians who use these agents in everyday practice." --Richard J. Glassock, MD, University of Kentucky College of Medicine, for DOODY'S PUBLISHING REVIEWS

• Eknoyan, History of Diuretics.Alpern, Giebisch, and Seldin, Renal Electrolyte Transport and Its Regulation.Herbert, Physiology of Diuretic Action.Freidman and Hebert, Site and Mechanism of Action of Diuretics.Zeidel, Special Diuretics.Navar, Renal Hemodynamic Effects of Diuretics.Palmer, Extra-Renal Effects of Diuretics.Ellison, Diuretic Use.Brater, Diuretic Pharmacokinetics and Pharmacodynamics. Resistance to Diuretic Drugs.Ellison, Adaptation to Diuretic Drugs.Patel and Kirchner, Use of Diuretics in Chronic Renal Disease and Nephrotic Syndrome.Kirchner, Effect of Prostaglandin Inhibition on the Action of Diuretic Agents.Kirchner, Impairment of Diuretic Secretion.Salem and Kirchner, Albumin as an Adjunct to Diuretics for the Treatment of Edema. Enhancement of Diuretic Action.Ellison, Intensive Diuretic Therapy: High Doses, Combinations, and Constant Infusions.Ellison, Circulatory Support, Dopamine, and Dopamine Agonists as Adjuncts to Diuretic Therapy.Cleland, Interactions between ACE Inhibitors and Diuretics.Struthers, Atrial Natriuretic Peptide.Emmett and Seldin, Indications Edematous States.Emmett and Seldin, The Pathophysiology of Edema Formation.Emmett and Seldin, Use of Diuretics for the Treatment of Heart Failure.Emmett and Seldin, Diuretic Treatment of Nephrotic Syndrome.Emmett and Seldin, The Use of Diuretics in the Treatment of Ascites and Edema in Hepatic Cirrhosis.Silkensen and Ferris, Diuretics in Pregnancy.Silkensen and Ferris, Idiopathic Edema.Unwin and Capasso, Hypertension and its Treatment: The Place of Diuretics.Star, Water and Electrolyte Derangements: Overhydration.Hsia, High Altitude Sickness.Palmer and Seldin, Diuretics in the Treatment of Metabolic Alkalosis.Beslau, Use of Diuretics in Disorders of Calcium Metabolism.Suki, Indications for the Use of Diuretics in Patients with Renal Impairment.Fenves, Toxic Agents: Drug Overdose, Poisons, Contrast Media.Schwartz, Glaucoma.Schwartz, Cerebral Edema.Star, Diuretic Complications.Rivera and Star, Sodium: Volume Depletion and Hyponatremia.Palmer, Potassium: Disturbances Associated with the Use of Diuretics.Palmer, Acid-Base: Disturbances Associated with the Use of Diuretics.Sakaee, The Effect of Diuretics on Ca Metabolism: Physiologic and Clinical Effects.Sakhaee, The Effect of Diuretics on Mg Metabolism: Physiologic and Clinical Effects.Toto, Metabolic Derangements Associated with Diuretic Use: Insulin Resistance, Dyslipidemia, Hyperuricemia, and Androgenic Effects.Star, Ototoxicity.Toto, Allergic Interstitial Nephritis Due to Diuretic Agents.Subject Index.