Essential Chemistry for Formulators of Semisolid and Liquid Dosages

Vitthal Kulkarni, Ph.D. is Scientific Advisor at DPT Laboratories San Antonio, Texas. After earning Ph.D. in Chemistry at National Chemical Laboratory, Pune, India in the area of surface/colloid chemistry, Dr. Kulkarni studied lipid monolayers, bilayers, self-assembled nano-structures, and protein electron crystallography at various institutions including Université de Provence, Marseille, France, JEOL Ltd., Tokyo, Japan, Vanderbilt University, Nashville, Tennessee, University of Minnesota, Austin, Minnesota and Yale University, New Haven, Connecticut before moving into industry. Dr. Kulkarni has been with DPT Laboratories since 2003.Dr. Kulkarni is experienced in developing and characterizing various non-invasive drug delivery systems including topical drug delivery systems comprised of liposomes, and nano-particles, emulsions and nasal spray products. He has published scientific research articles in peer reviewed journals, patents, book chapters, and edited a book titled Handbook of Non-Invasive Drug Delivery Systems: Science and Technology. He is a current member of American Association of Pharmaceutical Scientists. Charles Shaw, Ph.D. is Scientific Advisor at DPT Lakewood LLC, Lakewood, NJ. Dr. Shaw has more than 30 years of experience in pharmaceutical and medical device development and manufacturing, and holds board certifications that include Chartered Scientist; Chartered Chemist; Fellow of the Royal Society of Chemistry, London; and European Chemist. Before joining DPT Laboratories in 2004, he was Product Development and Technical Services Manager with Smith & Nephew Medical Ltd. He earned a Ph.D. in Chemistry at the University of Hull, England in the area of reaction kinetics.Dr. Shaw is experienced in the development and characterization of wound dressings, semi-solid and liquid formulations, and nasal spray products. He has published scientific research articles in peer reviewed journals, book chapters, trade journals and conferences. He has also presented webinars and conference workshops for nasal spray products. He is a current member of American Association of Pharmaceutical Scientists.

• 1. Introduction to the Chemistry of Mixing2. Surfactants, Lipids and Surface Chemistry3. Drug Delivery Vehicles4. Formulating Creams, Gels, Lotions and Suspensions5. Polymers and Thickeners in Semisolid Formulations6. Topical Aerosol and Nasal Sprays7. Formulation and Stability Testing8. Particle Size: An Overview of Various Methods9. Rheological/Viscosity Studies10. Microscopy Techniques (Optical and Electron Microscopy)11. Miscellaneous Physical, Chemical and Microbiological Test Methods12. An Overview of Regulatory Aspects for Pharmaceutical Semisolid Dosage