Lanzkowsky's Manual of Pediatric Hematology and Oncology

Jonathan D. Fish, MD is Assistant Professor of Pediatrics at the Hofstra Northwell School of Medicine. He is Director of the Survivors Facing Forward Program, a long-term follow-up program for survivors of childhood cancer, in the division of Pediatric Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children’s Medical Center of New York. He holds a B.A., with distinction, from the University of Western Ontario and received his M.D. degree, magna cum laude, from the Upstate Medical Center of the State University of New York. He did his Pediatric training at the the Schneider Children’s Hospital, New Hyde Park, NY ( Presently known as the Steven and Alexandra Children’s Medical Center of New York) and completed his Pediatric Hematology-Oncology fellowship training at the Children’s Hospital of Philadelphia. Dr. Fish received the American Society of Pediatric Hematology-Oncology Young Investigator Award in 2008. His clinical and research interest is on the late effects of childhood cancer treatment and survivorship care. Jeffrey M. Lipton, MD, PhD is the Chief of Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children’s Medical Center of New York and Center Head, Patient Oriented Research, The Feinstein Institute for Medical Research. He is Professor, Elmezzi Graduate School of Molecular Medicine, The Feinstein Institute for Medical Research and Professor of Pediatrics and Molecular Medicine at the Hofstra North Shore – LIJ School of Medicine. He holds a B.A. from Queens College, City University of New York, a Ph.D in Chemistry from Syracuse University and an M.D. degree, magna cum laude, from Saint Louis University Medical School. He did his Pediatric residency training at the Children’s Hospital, Boston, MA and his Pediatric Hematology/Oncology fellowship training at the Children’s Hospital and the Sidney Farber Cancer Institute (now DFCI) in Boston. Dr. Lipton is a Past-President of the American Society of Pediatric Hematology/Oncology (ASPHO). His main interest is bone marrow failure. Dr. Philip Lanzkowsky was born in Cape Town on March 17, 1932 and graduated high school from the South African College and obtained his MB ChB degree from the University of Cape Town School of Medicine in 1954 and his Doctorate degree in 1959 for his thesis on Iron Deficiency Anemia In Children. He completed a pediatric residency at the Red Cross War Memorial Children’s Hospital in Cape Town in 1960. After working in Pediatrics at the University of Edinburgh and at St Mary’s Hospital of the University of London, Dr. Lanzkowsky did a pediatric Hematology-Oncology fellowship at Duke University School of Medicine and at the University of Utah.In 1963 he was appointed Consultant Pediatrician and Pediatric Hematologist to the Red Cross War Memorial Children’s Hospital at the University of Cape Town and introduced Pediatric Hematology and Oncology as a distinct discipline. In 1965 he was appointed Director of Pediatric Hematology and Associate Professor of Pediatrics at the New York Hospital-Cornell University School of Medicine.In 1970 he was appointed Professor of Pediatrics and Chairman of Pediatrics at Long Island Jewish Medical Center and established a division of Pediatric Hematology-Oncology which he directed until 2000. He was the founder of the Schneider Children’s Hospital, which he developed, planned, and was the hospital’s Executive Director and Chief of Staff from its inception in 1983 until 2010.Dr. Lanzkowsky has received numerous honors and awards and has lectured extensively at various institutions and medical schools in the United States and around the world. In addition to having been the author of five editions of the Manual of Pediatric Hematology and Oncology used by clinicians worldwide, he is the author of How It All Began: The History of a Children’s Hospital and over 280 scientific papers, abstracts, monographs, and book chapters.Dr. Lanzkowsky’s medical writings have been prodigious. His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch. Dis Child., 1959), Effects of timing of clamping of umbilical cord on infant’s hemoglobin level (Br. Med. J., 1960), Normal oral D-xylose test values in children (New Engl. J. Med., 1963), Normal coagulation factors in women in labor and in the newborn (Thromboses at Diath. Hemorr., 1966), Erythrocyte abnormalities induced by malnutrition (Br. J. Haemat., 1967), Radiologic features in iron deficiency anemia (Am. J. Dis. Child., 1968), Isolated defect of folic acid absorption associated with mental retardation (Blood, 1969; Am. J. Med, 1970), Disaccharidase levels in iron deficiency (J. Pediat., 1981) and Hexokinase “New Hyde Park” in a Chinese kindred (Am. J. Hematol., 1981).

"I would like to applaud Professor Philip Lanzkowsky and his colleagues for the publication of the sixth edition of Lanzkowsky’s Manual of Pediatric Hematology and Oncology. As with the previous editions, the manual is a most practical tool for students, residents, and physicians in the field of hematology and oncology. It should automatically be on the list of required study for trainees and on the shelf on practicing clinicians. It provides valuable diagnostic algorithms, including state of the art diagnostic approaches and up-to-date therapeutic regimens, which influence decisions for management at the bedside. Dr. Lanzkowsky’s didactic approach, the product of over five decades of academic clinical practice, permeates the book, which is distinguished by its clarity and clinical relevance." --Isaac Yaniv, MD, Associate Professor of Pediatrics, Tel Aviv University, Chairman The Rina Zaizov Pediatric Hematology-Oncology division, Schneider Children’s Medical Center of Israel, Tel Aviv, Israel"The Lanzkowsky Manual was the first book I bought when I started my fellowship and to this day, I buy every new edition that comes out. It is my first choice ‘go-to’ for all subjects in pediatric hematology-oncology. The book is characterized by a clarity of style, packed with useful information which is easily accessible." --Kenan Onel, MD, PhD, Associate Professor of Pediatrics, Section of Hematology-Oncology, University of Chicago, Chicago, IL, USA"Lanzkowsky’s Manual of Pediatric Hematology and Oncology has deservedly earned a worldwide reputation as the standard authoritative text on the subject. Now in its sixth edition, with an expansion of contributing authors commensurate with the major developments in the field, Professor Lanzkowsky’s clarity of style and clinical relevance have remained the hallmarks of this book. It is an essential practical companion for clinicians in the field of pediatric hematology and oncology." --Victor Dubowitz, MB, ChB, MD, PhD, FRCP, FRCPH, Emeritus Professor of Pediatrics, University of London, London, UK"The Lanzkowsky Manual was the first manual I consulted when I was a resident interested in pediatric hematology and oncology; I loved its comprehensive and yet clear approach to so many topics. The manual has kept its unique place on my shelf over the years and the many editions since it was first published. I continue to consult it often for its practical guidance, and it remains a book of reference for me." --Carlos Rodriquez-Galindo, MD, Professor of Pediatrics, Harvard Medical School, Director Solid Tumor Program and Medical Director Pediatric Oncology Clinical Trials, Dana-Farber Cancer Institute, Boston, MA, USA"The sixth edition of the Manual of Pediatric Hematology and Oncology has now been retitled Lanzkowsky’s Manual of Pediatric Hematology and Oncology in recognition of the contribution of the original editor and guiding author for over 35 years. Like all the previous editions, this edition is a highly valuable resource providing the most up-to-date information in an accessible form focusing on practical clinical information. It is a "must consult" book for all clinicians in the field. The new chapters on transfusion medicine and diagnostic, molecular, and genomic methodologies are excellent additions reflecting recent progress in these areas. This edition has been enhanced by 51 highly regarded contributing authors who are leaders in their respective fields." --Kanti Rai MD, Past President, American Society of Hematology, Professor of Medicine and Professor of Molecular Medicine, Hofstra Northwell School of Medicine, Hempstead, NY, USA

• 1. Diagnostic, Molecular and Genomic Methodologies for the Hematologist / Oncologist Vijay G. Sankaran2. Hematologic Manifestations of Systemic IllnessLawrence C. Wolfe3. Classification and Diagnosis of Anemia in ChildrenLanzkowsky Philip4. Lymphadenopathy and SplenomegalyLanzkowsky Philip5. Anemia During the Neonatal PeriodLanzkowsky Philip6. Iron-Deficiency AnemiaLanzkowsky Philip7. Megaloblastic AnemiaLanzkowsky Philip8. Bone Marrow FailureJeffrey M. Lipton and Adrianna Vlachos 9. Hemolytic AnemiaLawrence C. Wolfe10. Red Cell Membrane and Enzyme DefectsLionel Blanc and Lawrence C. Wolfe 11. HemoglobinopathiesJanet L. Kwiatkowski12. PolycythemiaJosef T. Prchal and Tsewang Tashi 13. Disorders of White Blood CellsMary Ann Bonilla and Jill S. Menell 14. Disorders of PlateletsJames B. Bussel15. Disorders of Coagulation Suchitra S. Acharya16. Lymphoproliferative Disorders David T. Teachey17. MyelodysplasiaCharlotte Niemeyer and M. Tarek Elghetany 18. Lymphoid leukemiasWilliam L. Carroll and Teena Bhatla 19. Myeloid leukemiasArlene Sara Redner and Rachel Markowitz Kessel 20. Histiocytosis SyndromesRobert J. Arceci21. Hodgkin LymphomaDebra L. Friedman22. Non-Hodgkin LymphomaHoward Weinstein and Mary S. Huang 23. Central Nervous System MalignanciesMark P. Atlas24. NeuroblastomaBagatell Rochelle and Julie R. Park 25. Renal TumorsJeffrey Dome26. Rhabdomyosarcoma and Other Soft-Tissue SarcomasCarolyn Fein Levy and Leonard H. Wexler 27. Malignant Bone TumorsNoah Federman28. RetinoblastomaAnn-Marie Leahey29. Germ Cell TumorsThomas A. Olson30. Hepatic TumorsThomas A. Olson31. Hematopoietic Stem Cell TransplantationIndira Sahdev and Hisham Abdel-Azim 32. Management of Oncological EmergenciesSusan R. Rheingold33. Supportive Care of Patients with CancerJames H. Feusner and Anurag K. Agrawal 34. Evaluation, Investigation and Management of Late EffectsJonathan D. Fish35. Psychosocial Aspects of Cancer for Children and Their FamiliesMeg Tippy36. Transfusion Medicine Naomi L. C. Luban