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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Kemi
    4. Organisk kemi

    Discovery and Development of Antidiabetic Agents from Natural Products

    Natural Product Drug Discovery

    AvGoutam Brahmachari

    Häftad, Engelska, 2016

    Del i serien Natural Product Drug Discovery

    1 727 kr

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    E-bok

    2 285 kr

    Beskrivning

    Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic.

    Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications.

    Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics.



    • Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery
    • Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues
    • Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab

    Produktinformation

    • Utgivningsdatum:2016-11-01
    • Mått:152 x 229 x 18 mm
    • Vikt:690 g
    • Format:Häftad
    • Språk:Engelska
    • Serie:Natural Product Drug Discovery
    • Antal sidor:332
    • Förlag:Elsevier Science
    • ISBN:9780128094501

    Utforska kategorier

    • Organisk kemi inom Naturvetenskap och teknik

    Mer om författaren

    Dr. Goutam Brahmachari is a full professor of organic chemistry at Visva-Bharati University, Santiniketan, India. His research focuses on developing practical synthetic methods for carbon–carbon and carbon–heteroatom bonds using C–H functionalization, cascade, and cross-coupling techniques, with applications in medicinal heterocyclic scaffolds. He has also studied the chemistry and biology of traditionally used Indian medicinal plants, identifying novel phytochemicals of interest.He is the founding Series Editor of Elsevier’s Natural Product Drug Discovery book series and an elected fellow of the Royal Society of Chemistry. His awards include the Acharya P. C. Ray Memorial Lecture Award (2025) from the Indian Science News Association (ISNA), Kolkata, India; the Dr. Satyajit Chakraborti Memorial Award (2025) from IEM, Kolkata, India; the Chemical Research Society of India Bronze Medal (2021); the Dr. Basudev Banerjee Memorial Award (2021) from the Indian Chemical Society; the Indian National Science Academy Teachers Award (2019); the Dr. Kalam Best Teaching Faculty Award (2017); and the Academic Brilliance Award (2015).

    Innehållsförteckning

    • Chapter 1. Andrographolide: A Molecule of Antidiabetic PromiseChapter 2. Computer-Aided Discovery of Glycogen Phosphorylase Inhibitors Exploiting Natural ProductsChapter 3. Identification and Extraction of Antidiabetic Antioxidants from Natural SourcesChapter 4. Glucose Transporter 4 Translocation Activators From NatureChapter 5. Carbohydrate-Based Antidiabetic Agents From NatureChapter 6. Recent Developments on the Antidiabetic Sesquiterpene Lactones and Their Semisynthetic AnaloguesChapter 7. Prediction of Prediabetes and Its Prevention by Functional Food CompoundsChapter 8. Immunomodulators in Prophylaxis and Therapy of Type-1 DiabetesChapter 9. α-Glucosidase Enzyme Inhibitors From Natural ProductsChapter 10. Treasures of Indigenous Indian Herbal Antidiabetics: An Overview