Cannabinoid Pharmacology

David Kendall has had an active interest in cannabinoid research for over 20 years focussing initially on endocannabinoid signalling in the vascular system and latterly in its roles in pain. He was Professor of Pharmacology in the University of Nottingham Medical School until 2015 before taking up the position of Chief Scientific Officer for the drug discovery company PharmNovo. Dr Stephen Alexander has been interested in the regulation of mammalian cannabinoid systems since the first identification of an endogenous cannabinoid molecule in 1993. He has principally focused on the enzymes associated with the hydrolysis and transformation of these endocannabinoids, both in terms of establishing high throughput assays for these enzymes and also in quantifying their activities in tissues ex vivo. He is an Associate Professor of Molecular Pharmacology at the University of Nottingham, Chair of the Nomenclature Committee of the International Union of Basic and Clinical Pharmacology and has been President of the International Cannabinoid Research Society.

• 1. Endocannabinoids and their congenersFabiana Piscitelli2. Endocannabinoid turnoverSteve P.H Alexander3. Plant cannabinoidsEthan Russo4. Synthetic cannabinoids and ‘legal highs’Paco Molina-Holgado5. CB1 and CB2 cannabinoid receptorsMary Abood6. Novel signalling modalitiesDave Kendall7. Novel cannabinoid receptorsAndy Irving8. Ion channel regulation by cannabinoidsAlessia Ligresti9. Nuclear hormone receptors responding to cannabinoidsSaoirse O’Sullivan10. The cardiovascular systemVanessa Ho11. Metabolism and feedingJocelijn Meijerink12. Immune regulationScott Graham13. CancerBurkhard Hinz14. CNS: pain pathwaysDavid Finn