Mucosal Vaccines

"This book provides detailed information for basic scientists, physicians, and trainees interested in vaccine development, mucosal immunity, and immunology. The comprehensive references for each chapter provide readers with the opportunity to critically appraise the evidence level within, and to identify potential areas of scientific knowledge gaps or directions for future research." --Doody

• Introduction1. Why the Mucosal Immune System should be considered for the Development of Mucosal Vaccine2. Historical Perspectives on Mucosal VaccinesPrinciples of Mucosal Vaccines3. Anatomical Uniqueness of the Mucosal Immune System (DEVELOPMENTAL FOR STRUCTURES, E.G., Ibalt, GALT, NALT) for the Induction and Regulation of Mucosal Immunity & Tolerance4. Mucosal Antigen Sampling System (M Cells and Dendritic Cells)5. Essential Role of SIgA in Mucosal Immunity 6. Mucosal Lymphocyte Homing7. Innate Immunity at Mucosal Surfaces8. Induction and Regulation of Mucosal Memory B Cell Responses9. Induction and Regulation of Mucosal Memory T Cell Responses10. Influence of Commensal Miro-biota and –metabolite for mucosal immunity Mucosal Modulations for Induction of Effective Immunity11. Innate Immunity based Mucosal Modulator and Adjuvant12. Toxin-based Modulators for Regulation of Mucosal Immune Responses 13. Influence of Dietary (or Nutritional) Materials for the Control of Mucosal Immunity14. Mast Cells for the Control of Mucosal Immunity15. Innate Lymphoid Cells for the Control of Mucosal Immunity 16. Mucosal Regulatory System for Balanced Immunity in the Gut17. Mucosal Regulatory System for Balanced Immunity in the Genito-urinary Tract 18. Mucosal Regulatory System for Balanced Occular Immunity19. Mucosal Regulatory System for Balanced Oral Immunity 20. Mucosal Regulatory System for Balanced Immunity in the Middle EarCurrent and New Approaches for Mucosal Vaccine Delivery21. Mucosal Vaccine Delivery Systems 22. Plant-based Mucosal Vaccine Delivery Systems23. Plant-based Mucosal Immunotherapy 24. Attenuated Salmonella for Oral Immunization25. Recombinant BCG for Mucosal Immunity26. Recombinant Adenovirus for Mucosal Vaccine Delivery27. Mucosal Approaches for Systemic Immunity to Anthrax, Brucellosis and Plague28. Nano-Delivery Vehicles for Mucosal Vaccines29. Effectiveness of Sub-lingual Immunization 30. Antibody Approaches for Passive Mucosal Immune Protection31. M Cell-Targeted VaccinesMucosal Vaccines for Bacterial Diseases32. Mucosal Vaccines for Salmonella typhi Infection 33. Oral Vaccine for Shigella34. Oral Vaccines for Cholera35. Oral Vaccines for enterotoxinogenic E. coli (ETEC)36. Mucosal Immunity to Helicobacter pylori37. Mucosal Vaccines for Streptococcus pneumoniae38. Mucosal Vaccines for TB39. Mucosal Vaccines for Bacterial Sexually Transmitted Diseases 40. Mucosal Vaccines for Oral DiseasesMucosal Vaccines for Viral Diseases41. Mucosal RSV Vaccines42. Nasal Influenza Vaccines43. Development of Oral Rotavirus & Norovirus Vaccines 44. Rotavirus Vaccines--The Clinical Experience45. Mucosal Vaccines for HIV/SIV46. Mucosal Vaccines for Herpes 47. Maternal Antibodies for Protection Against Viral PathogensNew and Novel Approaches for Mucosal Vaccine Development 48. Systems Biology for Mucosal Vaccine Development49. Natural & Chemical Library for New Mucosal Modulators and Adjuvants 50. Commensal Bacteria-based Mucosal Vaccine Development 51. New Approaches for Vaccinating the Elderly Can Mucosal Vaccines be applied for other Infectious and Non-infectious Diseases?52. Mucosal Vaccine Development for Veterinary and Aquatic Diseases 53. Mucosal Vaccine for Malaria54. Mucosal Vaccine for Parasitic Infections55. Mucosal Vaccine for Allergy & Tolerance 56. Mucosal Immunity for Inflammation