• Fri frakt över 249 kr
  • •
  • Snabba leveranser
  • •
  • Billiga böcker
Kundservice

Du är på sajten för privatpersoner.

Företag, bibliotek eller offentlig verksamhet?

Du handlar på classic.bokus.com, där alla dina funktioner finns intakta.
Till classic.bokus.com
Bokus logotyp. Gå till startsidan.
  • Erbjudanden
  • Nyheter
  • Student
  • Topplistor
  • Barn & ungdom
  • Bokus Play
  • E-böcker
  • Pocketböcker
  • Spel & pussel

Upp till 20% på populära nyheter →

Sidfot

Mina sidor

    Hjälp

    • Kundservice
    • Vanliga frågor och svar
    • Frakt och leverans
    • Retur vid ångerrätt
    • Reklamera vara
    • Betalning
    • Köpvillkor
    • Allmänna villkor
    • Information om webbplatsens tillgänglighet

    Om Bokus

    • Om oss
    • Pressrum
    • För studenter
    • För företag
    • För bibliotek och offentlig verksamhet
    • För leverantörer
    • Hållbarhet

    Populärt

    • Aktuella erbjudanden
    • Presentkort
    • Studentlitteratur
    • Nya böcker
    • Topplistor
    • Signerade böcker
    • Engelska böcker

    Inspiration

    • Boktips
    • BookTok
    • Populära bokserier
    • Barnbokskaraktärer
    • Populära författare

    Mina sidor

      Hjälp

      • Kundservice
      • Vanliga frågor och svar
      • Frakt och leverans
      • Retur vid ångerrätt
      • Reklamera vara
      • Betalning
      • Köpvillkor
      • Allmänna villkor
      • Information om webbplatsens tillgänglighet

      Om Bokus

      • Om oss
      • Pressrum
      • För studenter
      • För företag
      • För bibliotek och offentlig verksamhet
      • För leverantörer
      • Hållbarhet

      Populärt

      • Aktuella erbjudanden
      • Presentkort
      • Studentlitteratur
      • Nya böcker
      • Topplistor
      • Signerade böcker
      • Engelska böcker

      Inspiration

      • Boktips
      • BookTok
      • Populära bokserier
      • Barnbokskaraktärer
      • Populära författare
      Logotyp för Bokus
      Följ oss på Facebook (extern länk)Följ oss på Instagram (extern länk)Följ oss på YouTube (extern länk)Följ oss på TikTok (extern länk)
      bokus @ CookiesIntegritetspolicyKöpvillkor
      Till Citymail hemsida (extern länk)Till Budbee hemsida (extern länk)Till Postnord hemsida (extern länk)Till Schenker hemsida (extern länk)Till Early Bird hemsida (extern länk)Till Walleys hemsida (extern länk)
      1. Medicin
      2. Andra medicinska specialiteter
      3. Farmakologi

      Artemisinin-Based and Other Antimalarials

      Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them

      AvGuoqiao Li,Ying Li

      Häftad, Engelska, 2017

      1 355 kr

      Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

      Beskrivning

      Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology.



      • Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria
      • Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development
      • Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

      Produktinformation

      • Utgivningsdatum:2017-11-28
      • Mått:152 x 229 x 22 mm
      • Vikt:1 130 g
      • Format:Häftad
      • Språk:Engelska
      • Antal sidor:736
      • Förlag:Elsevier Science
      • ISBN:9780128131336

      Utforska kategorier

      • Farmakologi inom Medicin

      Mer om författaren

      Professor Li graduated from Guangdong College of Traditional Chinese Medicine in 1955. He has more than 50-years experiences on Qinghaosu (artemisinin). He is the first to prove artemisinin’s curative effect on falciparum malaria and severe malaria, and contribute in qinghaosu (artemisinin) research in Project 523. He devised and researched a series of artemisinin-based combinations: dihydroartemisinin-piperaquine phosphate-primaquine combination (CV8) which was registered and produced in Vienam in 1997. It was the first-line treatment drug for malaria and given for free in Vietnam. Dihydroartemisinin-piperaquine phosphate combination, Artemisinin- piperaquine combination both have been registered and produced in China. Dihydroartemisinin-piperaquine combination was included in the 2nd edition of “Malaria treatment Guidelines” by WHO in 2010. He has published over 50 papers on malaria research and artemisinin derivatives. Ying Li received a Ph.D. in Miyagi, Japan, from Tohoku University. Currently a professor in Dalian Maritime University, China, Dr. Li is the Dean of the national key-field innovation team of maritime traffic safety and spatial information technology. For over 20 years, she has contributed to scientific research in the fields of intelligent perception of at-sea target and navigation environment, oil spill detection, waterborne intelligent transportation. Her credentials include: Member, expert committee of the Ministry of Transport, Dr. Li oversaw > 20 national and ministerial projects. Awarded > 30 national patents and been published in > 120 scientific papers. Awarded > 20 provincial and ministerial awards, including second prize for National Technological Invention, special prize for technological invention, Chinese Society of Navigation. Vice chair, “Digital Ocean” special committee, National Committee of International Digital Earth Society of China Vice chair, Navigation Remote Sensing Special Committee of Chinese Society of Navigation. Professor Li graduated from College of Pharmacology, Shanghai First Medical University in 1953. Li was a specialist dispatched by Division of Traditional Medicine, West Pacific Regional Office, WHO to give lecture on developing new drugs originating from herbal drugs in Vietnam in 1990. She identified the action site of plasmodium with electromicroscope autoradiography technology. She also identified that artemisinin series compounds could inhibit the metabolism of nucleic acid in plasmodium with in vitro culture. Li was engaged in studies on the pharmacodynamics, pharmacokinetics and special toxicity, such as teratogenicity and mutagenicity of artemisinim. Ms. Li was one of the main secretaries of the China Steering Committee of Qinghaosu, participating the design of the project and coordinating the work of individual research group to develop new anti-malaria drugs. Professor Zeng graduated from Faculty of Pharmaceutical Sciences, College of Medicine, Beijing University in1954 with diploma, 1954-1990 worked in the Department of Analytical Chemistry of Institute of Chinese Materia Medica under Academy of Traditional Chinese Medicine, with more than 35 years’ experience in chemical analysis.Professor Zeng developed the assay method for quality control of qinghaosu (artemisinin), and method for determination of dihydroartemisinin and improving method for assay of artemether in pharmaceutical substance. In 1986, Zhao Shishan and Zeng developed the HPLC method for determination of artemisinin in animal and human plasma and applied to analysis of plasma samples of falciparum patients after rectal administration of artemisinin suppositories

      Innehållsförteckning

      • 1. Discovery of Artemisinin and History of Research and Discovery of Artemisinin Antimalarials2. Biological Research of Artemisia annua L 3. Chemical Research on Artemisinin4. Artemisinin Derivatives and Analogues5. Pharmacological Study on Artemisinin and Its Derivatives6. Clinical Studies of Artemisinin and its Derivatives7. Artemether and Lumefantrine Combination 8. Artemisinin and Naphthoquine Phosphate Combination9. The Combination of Artemisinin Drugs and Pyronaridine10. Artemisinins and piperaquine phosphate combinations
      Hoppa över listan

      Mer från samma författare

      Meiyi Zeng, Zelin Li, Ying Li, Guoqiao Li - Artemisinin-Based and Other Antimalarials, E-bok

      Artemisinin-Based and Other Antimalarials

      Meiyi Zeng, Zelin Li, Ying Li, Guoqiao Li

      E-bok
      2017

      1 737 kr

      Hoppa över listan

      Du kanske också är intresserad av

      Meiyi Zeng, Zelin Li, Ying Li, Guoqiao Li - Artemisinin-Based and Other Antimalarials, E-bok

      Artemisinin-Based and Other Antimalarials

      Meiyi Zeng, Zelin Li, Ying Li, Guoqiao Li

      E-bok
      2017

      1 737 kr

      Yun Lin, Ying Li, Guan Gui - e-Learning, e-Education, and Online Training, E-bok

      e-Learning, e-Education, and Online Training

      Yun Lin, Ying Li, Guan Gui

      E-bok
      2024

      1 219 kr

      Jianli Zhao, Fengxia Zhang, Ying Li, Musheng Wei - Quaternion Matrix Computations, E-bok

      Quaternion Matrix Computations

      Jianli Zhao, Fengxia Zhang, Ying Li, Musheng Wei

      E-bok
      2018

      3 314 kr

      Ying Li - Oil Spill Detection, Identification, and Tracing, E-bok

      Oil Spill Detection, Identification, and Tracing

      Ying Li

      E-bok
      2023

      2 450 kr

      Ying Li, Jueming Hua, Lisheng Feng - The Art of Printing, Häftad

      The Art of Printing

      Ying Li, Jueming Hua, Lisheng Feng

      Häftad, 2025

      297 kr

      Ying Li, Farid Chemat - Plant Based “Green Chemistry 2.0”, Inbunden

      Plant Based “Green Chemistry 2.0”

      Ying Li, Farid Chemat

      Inbunden, 2019

      1 773 kr

      Yong-Gang Li, Yongxian Zhang, Zhongliang Wu, Ying Li, Xiaodong Zhang - Scientific Investigation of Continental Earthquakes and Relevant Studies, Häftad

      Scientific Investigation of Continental Earthquakes and Relevant Studies

      Yong-Gang Li, Yongxian Zhang, Zhongliang Wu, Ying Li, Xiaodong Zhang

      Häftad, 2026

      1 743 kr

      Guan Gui, Ying Li, Yun Lin - e-Learning, e-Education, and Online Training, Häftad
      Del 544

      e-Learning, e-Education, and Online Training

      Guan Gui, Ying Li, Yun Lin

      Häftad, 2024

      855 kr

      Michael Bloss, Dietmar Ernst, Joachim Häcker, Ying Li - Derivatives, Häftad

      Derivatives

      Michael Bloss, Dietmar Ernst, Joachim Häcker, Ying Li

      Häftad, 2009

      526 kr

      Guoyi Han, Ying Li, Peijun Shi - Understanding the Regional Dynamics of Vulnerability, Inbunden

      Understanding the Regional Dynamics of Vulnerability

      Guoyi Han, Ying Li, Peijun Shi

      Inbunden, 2027

      1 522 kr