Immunology of Endometriosis

Kaori Koga, M.D., Ph.D. is a physician-scientist and an Associate Professor of the Department of Obstetrics and Gynecology, School of Medicine at the University of Tokyo, Japan. Dr. Koga received her M.D. degree from Chiba University, Chiba, Japan, and her Ph.D. degree from the University of Tokyo. She undertook post-doctoral fellowships in the Uterine Biology Group (Prof. Lois Salamonsen’s laboratory) at Prince Henry’s Institute, Melbourne, Australia in 2006, and the Reproductive Immunology Unit (Prof. Gil Mor’s laboratory) at the Department of Obstetrics, Gynecology and Reproductive Sciences in Yale University in 2006–2008. Dr. Koga's keen interest lies in Reproductive Immunology, with particular focus on endometriosis and infertility. As a gynecological clinician, Dr. Koga has treated many patients with endometriosis and has performed Minimally Invasive Surgery and Aassisted Reproductive Technology. Dr. Koga has received numerous national and international awards, including Kanzawa Award from the Kanzawa Medical Research Foundation in 2018 and Guston Award from the American Society for Reproductive Immunology (ASRI) in 2008. She is a member of the ASRI, the International Society for Immunology of Reproduction (ISIR) as well as of the European Society of Human Reproduction and Embryology (ESHRE), and an ambassador of the World Endometriosis Society (WES). Dr Koga is an Associate Editor of Human Reproduction Open (2021–) and serves on the editorial boards of the American Journal of Reproductive Immunology, and the Journal of Reproductive Immunology.

• 1. B lymphocytesL.G.C. Riccio and M.S. Abrão2. Macrophages in endometriosis: they came, they saw, they conqueredKavita Panir, Mary Louise Hull, and Erin Greaves3. Dendritic cellsGentaro Izumi4. Immune factors in the pathogenesis and the potential therapeutic target of endometriosis 1e4 neutrophilsMasashi Takamura5. Role of Th1, Th2, Th17, and regulatory T cells in endometriosisKhaleque N. Khan, Akira Fujishita, Yukiko Tanaka, and Jo Kitawaki6. Auto-immunity and endometriosis: evidence, mechanism and therapeutic potentialTao Zhang, Tin-Chiu Li, and Chi-Chiu Wang7. Role of estrogen and estrogen-related factors in endometriosisTaisuke Mori and Jo Kitawaki8. Immune factors in the pathogenesis and the potential therapeutic target of endometriosisWan-Ning Li, Meng Hsing Wu, and Shaw-Jenq Tsai9. The roles and functions of macrophages in endometriosisMiaomiao Ji, Xue Jiao, Sun-Wei Guo, and Guoyun Wang10. The role of immune factors in endometriosis-related conditions, 2-1 painFabio Barra, Giulio Evangelisti, Carolina Scala, and Simone Ferrero11. Immune phenotypes and mediators affecting endometrial function in women with endometriosisLinda C. Giudice and Julia Vallve Juanico12. The role of immune factors in endometriosis-related conditions, 2e3 ovarian dysfunctionMichio Kitajima13. The role of immune-related redox biology in malignant transformation of endometriosisHiroshi Kobayashi14. Pregnancy complicationsLouis Marcellin, Pietro Santulli, and Charles Chapron15. Prevalent innate and adaptive immune mechanisms in endometriosisRyan M. Marks, Harshavardhan Lingegowda, Alison McCallion, Anushka Nair, and Chandrakant Tayade16. Novel therapeutic strategy: antiinflammatory reagentsHiroaki Komatsu, Fuminori Taniguchi, and Tasuku Harada17. Gut microbiota and endometriosisOsamu Yoshino, Yosuke Ono, and Takehiro Hiraoka18. Immunosuppression and immunotherapy in endometriosis: review of pathophysiology, recent development and future perspectivesYing He, Kennes Sze Wan Hung, Hui Xu, and Chi Chiu Wang19. Novel diagnostic strategies for endometriosisMathew Leonardi, Jodie Avery, and M. Louise Hull