The Design of Covalent-Based Inhibitors

Inbunden, Engelska, 2021

Del 56 i serien Annual Reports in Medicinal Chemistry

2 193 kr

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Beskrivning

Annual Report on Medicinal Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in the Annual Report on Medicinal Chemistry series
Updated release includes the latest information on The Design of Covalent-Based Inhibitors

Produktinformation

Utgivningsdatum:2021-07-09
Mått:152 x 229 x 20 mm
Vikt:610 g
Format:Inbunden
Språk:Engelska
Serie:Annual Reports in Medicinal Chemistry
Antal sidor:298
Förlag:Elsevier Science
ISBN:9780128216897

Utforska kategorier

Farmakologi inom Medicin
Kemi inom Naturvetenskap och teknik

Mer om författaren

Richard A. Ward is at AstraZeneca, UK Neil Grimster is at AstraZeneca, USA

Innehållsförteckning

PrefaceRichard Andrew Ward and Neil Grimster1. The history of covalent inhibitorsRenato A. Bauer2. Kinetic Mechanisms of Covalent InhibitionClaire Louise McWhirter3. Covalent Drugs in Development for Immune-Mediated DiseasesLeonard Sung4. Chemistry Perspectives of Reversible Covalent DrugsJianmin Gao5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond CysteineLyn Jones6. Boron and Covalent InhibitionAndrew Leach7. Measuring and predicting warhead and residue reactivityChristopher Rowley8. Computational Support of Structure-based Targeted Covalent Inhibitor DesignRobert Abel9. Novel approaches to covalent inhibitionNir London10. The future of covalent inhibitionGyorgy M. Keseru